Denis Pezet
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View article: Chemotherapy effects on mitochondrial function in adipose tissue in oesophageal and gastroesophageal junction adenocarcinomas with or without associated cachexia: protocol for a prospective, comparative observational study (ChiFMeOE)
Chemotherapy effects on mitochondrial function in adipose tissue in oesophageal and gastroesophageal junction adenocarcinomas with or without associated cachexia: protocol for a prospective, comparative observational study (ChiFMeOE) Open
Introduction Cachexia is strongly associated with digestive cancers, particularly oesogastric cancer. Mitochondria in adipose tissue are involved in the regulation of metabolism and physiopathology of cancer cachexia in animal studies. Che…
View article: Increased levels of anti-Encephalitozoon intestinalis antibodies in patients with colorectal cancer
Increased levels of anti-Encephalitozoon intestinalis antibodies in patients with colorectal cancer Open
Background The prevalence of microsporidiosis in the general population, or within specific groups of individuals/patients, is largely underestimated. The absence of specific seroprevalence tools limits knowledge of the epidemiology of the…
View article: Clinico-biological factors predicting the benefit of the LV5FU2 maintenance strategy as a first-line therapy in patients with metastatic pancreatic cancer
Clinico-biological factors predicting the benefit of the LV5FU2 maintenance strategy as a first-line therapy in patients with metastatic pancreatic cancer Open
Introduction Predictive markers of LV5FU2 maintenance benefit after first-line induction with FOLFIRINOX in patients with metastatic pancreatic cancer are necessary to select patients who will not be harmed by this strategy. Patients and M…
View article: FOLFIRI Plus Durvalumab With or Without Tremelimumab in Second-Line Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
FOLFIRI Plus Durvalumab With or Without Tremelimumab in Second-Line Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma Open
Importance Efficacy of second-line chemotherapy in advanced gastric or gastrooesphageal junction (GEJ) adenocarcinoma remains limited. Ojectives To determine the efficacy of 1 or 2 immune checkpoint inhibitors combined with FOLFIRI (leucov…
View article: Colibactin-producing <i>Escherichia coli</i> enhance resistance to chemotherapeutic drugs by promoting epithelial to mesenchymal transition and cancer stem cell emergence
Colibactin-producing <i>Escherichia coli</i> enhance resistance to chemotherapeutic drugs by promoting epithelial to mesenchymal transition and cancer stem cell emergence Open
Human colorectal cancers (CRCs) are readily colonized by colibactin-producing E. coli (CoPEC). CoPEC induces DNA double-strand breaks, DNA mutations, genomic instability, and cellular senescence. Infected cells produce a senescence-associa…
View article: A phase-II study based on dose adjustment according to UGT1A1 polymorphism: is irinotecan underdosed in first-line FOLFIRI regimen for mCRC?
A phase-II study based on dose adjustment according to UGT1A1 polymorphism: is irinotecan underdosed in first-line FOLFIRI regimen for mCRC? Open
Purpose Irinotecan has considerable importance in the treatment of metastatic colorectal cancer (mCRC). UDP-glucoronyltransferase (UGT) 1A1 is responsible for the inactivation of SN-38, a metabolite of irinotecan. Depending on UGT1A1 polym…
View article: Supplementary figure 1, Supplementary figure 2,Supplementary figure 3,Supplementary figure 4 from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care
Supplementary figure 1, Supplementary figure 2,Supplementary figure 3,Supplementary figure 4 from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care Open
Supplementary figure 1: overall survival general data Supplementary figure 2: relation of ccfDNA parameters with clinical variables Supplementary figure 3: Kaplan Meier curves in mutant mCRC patients in function of mA with exclusion of the…
View article: supplementary methods from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care
supplementary methods from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care Open
rationale for sample size of the studied cohort
View article: Data from Colonization of the Human Gut by <i>E. coli</i> and Colorectal Cancer Risk
Data from Colonization of the Human Gut by <i>E. coli</i> and Colorectal Cancer Risk Open
Purpose: The intestinal microbiota is potentially involved in the development of colorectal carcinoma via various mechanisms. Escherichia coli are commensal bacteria of the human gut microbiota, but some pathogenic strains have acquired th…
View article: Data from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care
Data from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care Open
Purpose: Circulating cell-free DNA (ccfDNA) is a valuable source of tumor material obtained from a simple blood sampling that enables noninvasive analysis of the tumor genome. Our goal was to carry out a multiparametric analysis of ccfDNA …
View article: Supplementary Table 1 from Colonization of the Human Gut by <i>E. coli</i> and Colorectal Cancer Risk
Supplementary Table 1 from Colonization of the Human Gut by <i>E. coli</i> and Colorectal Cancer Risk Open
PDF file - 47K, Table A: The presence of mucosa-associated or internalized E. coli in the tissues of colon 542 cancer patients according to clinical characteristics.
View article: Data from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care
Data from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care Open
Purpose: Circulating cell-free DNA (ccfDNA) is a valuable source of tumor material obtained from a simple blood sampling that enables noninvasive analysis of the tumor genome. Our goal was to carry out a multiparametric analysis of ccfDNA …
View article: Supplementary Figures 1 - 3 from Colonization of the Human Gut by <i>E. coli</i> and Colorectal Cancer Risk
Supplementary Figures 1 - 3 from Colonization of the Human Gut by <i>E. coli</i> and Colorectal Cancer Risk Open
PDF file - 1963K, Figure A: TNM stage in relation to the mucosal proliferative index measured by Ki-67 immunostaining. Figure B: Colonization of the mucosa or tumor by E. coli in relation to the presence of B2 phylotype E. coli strains. Fi…
View article: Supplementary information from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care
Supplementary information from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care Open
Relation of ccfDNA parameters and CEA values with tumor burden
View article: Supplementary information from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care
Supplementary information from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care Open
Relation of ccfDNA parameters and CEA values with tumor burden
View article: supplementary methods from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care
supplementary methods from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care Open
rationale for sample size of the studied cohort
View article: Supplementary Figure Legend from Colonization of the Human Gut by <i>E. coli</i> and Colorectal Cancer Risk
Supplementary Figure Legend from Colonization of the Human Gut by <i>E. coli</i> and Colorectal Cancer Risk Open
PDF file - 20K
View article: Supplementary figure 1, Supplementary figure 2,Supplementary figure 3,Supplementary figure 4 from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care
Supplementary figure 1, Supplementary figure 2,Supplementary figure 3,Supplementary figure 4 from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care Open
Supplementary figure 1: overall survival general data Supplementary figure 2: relation of ccfDNA parameters with clinical variables Supplementary figure 3: Kaplan Meier curves in mutant mCRC patients in function of mA with exclusion of the…
View article: Supplementary table 1, supplementary table 2 from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care
Supplementary table 1, supplementary table 2 from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care Open
supplementary Table 1: detailed data of included patients supplementary table 2: relation of ccfDNA parameters with clinical variables.
View article: supplementary methods from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care
supplementary methods from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care Open
assay description of the Intplex method
View article: Supplementary Table 1 from Colonization of the Human Gut by <i>E. coli</i> and Colorectal Cancer Risk
Supplementary Table 1 from Colonization of the Human Gut by <i>E. coli</i> and Colorectal Cancer Risk Open
PDF file - 47K, Table A: The presence of mucosa-associated or internalized E. coli in the tissues of colon 542 cancer patients according to clinical characteristics.
View article: Supplementary table 1, supplementary table 2 from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care
Supplementary table 1, supplementary table 2 from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care Open
supplementary Table 1: detailed data of included patients supplementary table 2: relation of ccfDNA parameters with clinical variables.
View article: Data from Colonization of the Human Gut by <i>E. coli</i> and Colorectal Cancer Risk
Data from Colonization of the Human Gut by <i>E. coli</i> and Colorectal Cancer Risk Open
Purpose: The intestinal microbiota is potentially involved in the development of colorectal carcinoma via various mechanisms. Escherichia coli are commensal bacteria of the human gut microbiota, but some pathogenic strains have acquired th…
View article: Supplementary Figures 1 - 3 from Colonization of the Human Gut by <i>E. coli</i> and Colorectal Cancer Risk
Supplementary Figures 1 - 3 from Colonization of the Human Gut by <i>E. coli</i> and Colorectal Cancer Risk Open
PDF file - 1963K, Figure A: TNM stage in relation to the mucosal proliferative index measured by Ki-67 immunostaining. Figure B: Colonization of the mucosa or tumor by E. coli in relation to the presence of B2 phylotype E. coli strains. Fi…
View article: supplementary methods from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care
supplementary methods from Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care Open
assay description of the Intplex method