Doo Sun Sim
YOU?
Author Swipe
View article: Long-term outcomes according to absolute value vs. percentage reduction in low-density lipoprotein cholesterol levels after acute myocardial infarction
Long-term outcomes according to absolute value vs. percentage reduction in low-density lipoprotein cholesterol levels after acute myocardial infarction Open
Backgrounds/aims Real-world data are limited regarding long-term outcomes in terms of absolute follow-up values of low-density lipoprotein cholesterol (LDL-C) vs. percentage reductions from baseline after LDL-C-lowering therapy for patient…
View article: Differential Outcomes of Beta-Blockers According to Heart Rate Following Myocardial Infarction with Reduced Left Ventricular Ejection Fraction
Differential Outcomes of Beta-Blockers According to Heart Rate Following Myocardial Infarction with Reduced Left Ventricular Ejection Fraction Open
In patients with AMI-rEF, beta-blockers were not independently associated with significantly reduced all-cause death after adjustment, though a trend was observed. Notably, beta-blocker use increased the risk of nonfatal myocardial infarct…
View article: Clinical Relevance of Fractional Flow Reserve‐Guided Percutaneous Coronary Intervention According to Left Ventricular Ejection Fraction in Patients With Acute Myocardial Infarction and Multivessel Disease
Clinical Relevance of Fractional Flow Reserve‐Guided Percutaneous Coronary Intervention According to Left Ventricular Ejection Fraction in Patients With Acute Myocardial Infarction and Multivessel Disease Open
Background Fractional flow reserve (FFR)‐guided or angiography‐guided complete revascularization has not been evaluated in patients with acute myocardial infarction (AMI) with multivessel disease and reduced left ventricular ejection fract…
View article: Chlorogenic acid attenuates cardiac hypertrophy and fibrosis by downregulating galectin 3
Chlorogenic acid attenuates cardiac hypertrophy and fibrosis by downregulating galectin 3 Open
Chlorogenic acid, an ester of caffeic acid and quinic acid, is found in foods such as eggplant and peaches. Its role in heart disease remains poorly understood. This study investigated whether chlorogenic acid affects cardiac hypertrophy a…
View article: Novel artificial intelligence model using electrocardiogram for detecting acute myocardial infarction needing revascularization
Novel artificial intelligence model using electrocardiogram for detecting acute myocardial infarction needing revascularization Open
Aims Rapid myocardial revascularization in patients with acute myocardial infarction (AMI) is essential to improve clinical outcomes. There is still room for improvement in the timely diagnosis of AMI. This study aimed to develop an artifi…
View article: Myocardial infarction and pulmonary embolism in pancreatic cancer: a case report of two manifestations of Trousseau's syndrome
Myocardial infarction and pulmonary embolism in pancreatic cancer: a case report of two manifestations of Trousseau's syndrome Open
Introduction The simultaneous occurrence of acute myocardial infarction (AMI) and venous thromboembolism (VTE) is rare and often associated with underlying malignancies. This study reports a rare case of concurrent AMI and pulmonary thromb…
View article: Intratracheal Delivery of a Phospholamban Decoy Peptide Attenuates Cardiac Damage Following Myocardial Infarction
Intratracheal Delivery of a Phospholamban Decoy Peptide Attenuates Cardiac Damage Following Myocardial Infarction Open
Heart failure (HF) remains a major cause of mortality worldwide. While novel approaches, including gene and cell therapies, show promise, efficient delivery methods for such biologics to the heart are critically needed. One emerging strate…
View article: Impact of renal function on treatment strategies and clinical outcomes in acute myocardial infarction patients with multivessel disease
Impact of renal function on treatment strategies and clinical outcomes in acute myocardial infarction patients with multivessel disease Open
CR improved outcomes in patients with eGFR ≥60, whereas no difference was observed between CR and IR in those with eGFR <60. Therefore, IR may be a viable option for patients with reduced renal function.
View article: Twenty-Year Clinical Experience of the Korea Acute Myocardial Infarction Registry
Twenty-Year Clinical Experience of the Korea Acute Myocardial Infarction Registry Open
The Korea Acute Myocardial Infarction Registry (KAMIR) was established in 2005 to address the paucity of large-scale, real-world evidence on acute myocardial infarction (AMI) in East Asia. Over the last 2 decades, KAMIR has enrolled more t…
View article: Differential statin intensity and outcomes in patients following myocardial infarction with very low low-density lipoprotein cholesterol
Differential statin intensity and outcomes in patients following myocardial infarction with very low low-density lipoprotein cholesterol Open
Statin intensity appeared to have no significant impact on clinical outcomes in AMI patients with LDL-C levels < 55 mg/dL. These results underscore the need for further investigations aimed at refining treatment strategies for this specifi…
View article: Coronary vasospasm and cardiovascular outcomes in patients with isolated myocardial bridging: A retrospective study
Coronary vasospasm and cardiovascular outcomes in patients with isolated myocardial bridging: A retrospective study Open
The presence of CVS adversely affects clinical outcomes in patients with MB. Further prospective clinical studies are required to confirm this association.
View article: Impact of Total Coronary Occlusion on Long-term Outcomes in Patients with ST-segment Elevation Myocardial Infarction
Impact of Total Coronary Occlusion on Long-term Outcomes in Patients with ST-segment Elevation Myocardial Infarction Open
Purpose: This study aimed to investigate the impact of preprocedural total coronary occlusion on long-term cardiovascular outcomes in patients with ST-segment elevation myocardial infarction (STEMI) in the contemporary percutaneous coronar…
View article: The Effects of Nicotine on Re-endothelialization, Inflammation, and Neoatherosclerosis After Drug-Eluting Stent Implantation in a Porcine Model
The Effects of Nicotine on Re-endothelialization, Inflammation, and Neoatherosclerosis After Drug-Eluting Stent Implantation in a Porcine Model Open
Nicotine inhibited re-endothelialization and promoted inflammation and NIH after PCI with DES in a porcine model.
View article: Ten-year trends in lipid management among patients after myocardial infarction in South Korea
Ten-year trends in lipid management among patients after myocardial infarction in South Korea Open
Background Dyslipidemia is an important risk factor for acute myocardial infarction. However, real-world data on its prevalence and lipid management trends for Korean patients with acute myocardial infarction are limited. This study aimed …
View article: Comparison of Clinical Outcomes between Drug-Eluting Balloons and Drug-Eluting Stents in Patients with Small Coronary Artery Disease
Comparison of Clinical Outcomes between Drug-Eluting Balloons and Drug-Eluting Stents in Patients with Small Coronary Artery Disease Open
Background/Aims: Drug-eluting balloons (DEBs) represent a novel therapeutic approach for patients with small coronary artery disease. However, further studies are needed to compare the clinical efficacy of DEBs versus drug-eluting stents (…
View article: Optimal timing of revascularization for patients with non-ST segment elevation myocardial infarction and severe left ventricular dysfunction
Optimal timing of revascularization for patients with non-ST segment elevation myocardial infarction and severe left ventricular dysfunction Open
Optimal timing of revascularization for patients who presented with non-ST segment elevation myocardial infarction (NSTEMI) and severe left ventricular (LV) dysfunction is unclear. A total of 386 NSTEMI patients with severe LV dysfunction …
View article: Timing of fractional flow reserve-guided complete revascularization in patients with ST-segment elevation myocardial infarction with multivessel disease: Rationale and design of the OPTION-STEMI trial
Timing of fractional flow reserve-guided complete revascularization in patients with ST-segment elevation myocardial infarction with multivessel disease: Rationale and design of the OPTION-STEMI trial Open
gov. Unique identifier: NCT04626882; and URL: https://cris.nih.go.kr. Unique identifier: KCT0004457.
View article: First-in-Human Evaluation of a Polymer-Free Everolimus-Eluting Stent Using a Titanium Dioxide Film
First-in-Human Evaluation of a Polymer-Free Everolimus-Eluting Stent Using a Titanium Dioxide Film Open
Trial Registration: Clinical Research Information Service Identifier: KCT0005699.
View article: Clinical Outcome after Everolimus-Eluting Stent Implantation for Small Vessel Coronary Artery Disease: XIENCE Asia Small Vessel Study
Clinical Outcome after Everolimus-Eluting Stent Implantation for Small Vessel Coronary Artery Disease: XIENCE Asia Small Vessel Study Open
There are limited data on outcomes after implantation of everolimus-eluting stents (EES) in East Asian patients with small vessel coronary lesions. A total of 1,600 patients treated with XIENCE EES (Abbott Vascular, CA, USA) were divided i…
View article: Risk of Bleeding and Ischemia in Elderly East Asian Patients with Diabetes Mellitus Treated with either Clopidogrel or Ticagrelor: From the Korean Acute Myocardial Infarction Registry-V
Risk of Bleeding and Ischemia in Elderly East Asian Patients with Diabetes Mellitus Treated with either Clopidogrel or Ticagrelor: From the Korean Acute Myocardial Infarction Registry-V Open
Prescribing a P2Y12 inhibitor for patients with diabetes mellitus (DM) and acute myocardial infarction (AMI) who have undergone percutaneous coronary intervention (PCI) is challenging because of the risk of bleeding and ischemia. We compar…
View article: Pre-Hospital Delay and Outcomes in Myocardial Infarction With Nonobstructive Coronary Arteries
Pre-Hospital Delay and Outcomes in Myocardial Infarction With Nonobstructive Coronary Arteries Open
Late presentation is associated with higher mortality in patients with MINOCA. Multidisciplinary efforts are needed to reduce pre-hospital delay, thereby improving the clinical outcomes in these patients.