D. Sivaraman
YOU?
Author Swipe
View article: Exploring the Inhibitory Potential of Podolactone B against Human Acetylcholinesterase: A Docking Study
Exploring the Inhibitory Potential of Podolactone B against Human Acetylcholinesterase: A Docking Study Open
In this work, a novel therapeutic drug for treating Alzheimer's disease is molecularly simulated. The cholinergic hypothesis is the treatment approach used in this investigation. With a substance derived from the natural podocarpus derivat…
View article: Anti-inflammatory and anti-arthritic activities of ethanolic extract of Myxopyrum serratulum A.W. Hill
Anti-inflammatory and anti-arthritic activities of ethanolic extract of Myxopyrum serratulum A.W. Hill Open
Background Rheumatoid arthritis (RA) is a debilitating inflammatory disorder characterized by an overactive immune system targeting joints, leading to inflammation and intense pain. While current RA therapies effectively alleviate symptoms…
View article: Exploring the Therapeutic Potential of Camalexin in Benomyl- induced Parkinson’s Disease in Mice: In vitro, In vivo and Aldehyde Dehydrogenase Insights
Exploring the Therapeutic Potential of Camalexin in Benomyl- induced Parkinson’s Disease in Mice: In vitro, In vivo and Aldehyde Dehydrogenase Insights Open
Camalexin was selected in this study due to its ALDH-enhancing gene and its aldehyde dehydrogenase and dopamine protective roles have been evaluated. Also, the role of Benomyl in affecting the aldehyde dehydrogenase enzyme (both ALDH1A1 an…
View article: Maleimide conjugated PEGylated liposomal antibiotic to combat multi-drug resistant Escherichia coli and Klebsiella pneumoniae with enhanced wound healing potential
Maleimide conjugated PEGylated liposomal antibiotic to combat multi-drug resistant Escherichia coli and Klebsiella pneumoniae with enhanced wound healing potential Open
Antibiotic resistance is a significant threat, leaving us vulnerable to bacterial infections. Novel strategies are needed to combat bacterial resistance beyond discovering new antibiotics. This research focuses on using maleimide conjugate…
View article: Contents
Contents Open
View article: Use of Injectable Platelet-Rich Fibrin Accompanied by Bone Graft in Socket Endurance: A Radiographic and Histological Study
Use of Injectable Platelet-Rich Fibrin Accompanied by Bone Graft in Socket Endurance: A Radiographic and Histological Study Open
Background Ridge preservation became a crucial dental health issue and strategy to keep away from ridge defacement after post-tooth loss. The recent scientific evolution of platelet-rich fibrin (PRF) comprises a parenteral formulation of P…
View article: An in-silico approach of assessments of human serotonin transporter inhibitory potential of various flavonoids for anti-depressants: molecular docking, MM-GBSA, molecular dynamics simulation studies
An in-silico approach of assessments of human serotonin transporter inhibitory potential of various flavonoids for anti-depressants: molecular docking, MM-GBSA, molecular dynamics simulation studies Open
Depression is one of the typical CNS disorders. Millions of people suffer from depression, a chronic illness with economic consequences. Tricyclic antidepressants, selective dopamine reuptake inhibitors, selective norepinephrine reuptake i…
View article: Letter in response to: Alamer A, Alrashed AA, Alfaifi M, et al. Effectiveness and safety of favipiravir compared to supportive care in moderately to critically ill COVID-19 patients: a retrospective study with propensity score matching sensitivity analysis. Curr Med Res Opin. 2021;19:1–13. DOI: 10.1080/03007995.2021.1920900
Letter in response to: Alamer A, Alrashed AA, Alfaifi M, et al. Effectiveness and safety of favipiravir compared to supportive care in moderately to critically ill COVID-19 patients: a retrospective study with propensity score matching sensitivity analysis. Curr Med Res Opin. 2021;19:1–13. DOI: 10.1080/03007995.2021.1920900 Open
View article: ACE2 downregulation promotes thrombosis and cardiac injury in COVID-19 patients
ACE2 downregulation promotes thrombosis and cardiac injury in COVID-19 patients Open
The outbreak of novel coronavirus disease (COVID-19) caused by SARS-CoV-2 severely challenges the economic stability of countries around the globe. Immune responses induced by active infection and vaccination have resulted in severe compli…
View article: Insight into Indian strategy on combating COVID-19
Insight into Indian strategy on combating COVID-19 Open
View article: Acute and subacute toxicity profiles on siddha drug Thulasi Ennai in wistar rats
Acute and subacute toxicity profiles on siddha drug Thulasi Ennai in wistar rats Open
Medicinal plants have been used in traditional medicines for their unmatched availability of bioactive compounds. Asthma is the most common chronic disease among children worldwide. It is ranked 16th among the leading causes of years lived…
View article: Risk–benefit analysis on the clinical significance of convalescent plasma therapy in the management of COVID-19
Risk–benefit analysis on the clinical significance of convalescent plasma therapy in the management of COVID-19 Open
The pandemic triggered by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is already on the list of the greatest threat that human beings have ever encountered in modern history. In the present scenario, SARS-CoV-2 has bec…
View article: Mineral Content in DBM and its Influence on Peri-implant Tissues: An In Vivo Study
Mineral Content in DBM and its Influence on Peri-implant Tissues: An In Vivo Study Open
View article: Public Health Awareness and Knowledge Dissemination Essen-tially Becomes a Need of the Hour in Combating COVID-19
Public Health Awareness and Knowledge Dissemination Essen-tially Becomes a Need of the Hour in Combating COVID-19 Open
This article is a Letter to the Editor and does not include an Abstract.
View article: Revealing Potential Binding Affinity of FDA Approved Therapeutics Targeting Main Protease (3CLpro) in Impairing Novel Coronavirus (SARSCoV- 2) Replication that Causes COVID-19
Revealing Potential Binding Affinity of FDA Approved Therapeutics Targeting Main Protease (3CLpro) in Impairing Novel Coronavirus (SARSCoV- 2) Replication that Causes COVID-19 Open
Background: Spread of COVID-19 attains a crucial transition in reveling its pandemic across the boundaries. In combating the infection caused by SARS-CoV-2, there is a spectrum of ideal strategies that have been adopted globally, of which …
View article: Exploration of bioflavonoids targeting dengue virus NS5 RNA-dependent RNA polymerase: In silico molecular docking approach
Exploration of bioflavonoids targeting dengue virus NS5 RNA-dependent RNA polymerase: In silico molecular docking approach Open
Progression of hepatic encephalopathy induced by bile duct ligation versus thioacetamide in rats: Regulatory role of apigeninAhmed M. Fayez, Dina F. Mansour, Dalia O. Saleh
View article: Scope of phytotherapeutics in targeting ACE2 mediated Host-Viral Interface of SARS‐CoV2 that causes COVID-19
Scope of phytotherapeutics in targeting ACE2 mediated Host-Viral Interface of SARS‐CoV2 that causes COVID-19 Open
Severe acute respiratory syndrome coronavirus (SARS-CoV-2) that cause COVID-19 becomes a global threat and spread its pandemicity across the boundaries. Recent demography issued by WHO forecasting the severity of disease prevalence in more…
View article: Scope of phytotherapeutics in targeting ACE2 mediated Host-Viral Interface of SARS‐CoV2 that causes COVID-19
Scope of phytotherapeutics in targeting ACE2 mediated Host-Viral Interface of SARS‐CoV2 that causes COVID-19 Open
Severe acute respiratory syndrome coronavirus (SARS-CoV-2) that cause COVID-19 becomes a global threat and spread its pandemicity across the boundaries. Recent demography issued by WHO forecasting the severity of disease prevalence in more…
View article: Current Strategies and Approaches in Combating SARS-CoV-2 Virus that Causes COVID-19
Current Strategies and Approaches in Combating SARS-CoV-2 Virus that Causes COVID-19 Open
The pandemic spread of severe acute respiratory syndrome coronavirus (SARS-CoV-2) that causes COVID-19 calls for global health emergency with wide prevalence across 94 countries, and around 3073 deaths reported in china on 7th March 2020 w…
View article: Revealing Anti-viral Potential of Bio-active Therapeutics Targeting SARS-CoV2- polymerase (RdRp) in Combating COVID-19: Molecular Investigation on Indian Traditional Medicines
Revealing Anti-viral Potential of Bio-active Therapeutics Targeting SARS-CoV2- polymerase (RdRp) in Combating COVID-19: Molecular Investigation on Indian Traditional Medicines Open
Spread of severe acute respiratory syndrome coronavirus (SARS-CoV-2) made a historic transition between December 2019 to March 2020. In the present scenario SARS-CoV-2 as becomes a major burden on public health and economic stability of so…
View article: Meet Our Associate Editorial Board Member
Meet Our Associate Editorial Board Member Open
View article: Structural biology oriented predicative analysis of immunogenic epitopes on SARS-CoV-2 viral sequence by variable algorithms
Structural biology oriented predicative analysis of immunogenic epitopes on SARS-CoV-2 viral sequence by variable algorithms Open
View article: TERATOGENICITY TESTING OF SIDDHA FORMULATION OF NILAVEMBU KUDINEER ON ZEBRAFISH (DANIO RERIO) EMBRYO
TERATOGENICITY TESTING OF SIDDHA FORMULATION OF NILAVEMBU KUDINEER ON ZEBRAFISH (DANIO RERIO) EMBRYO Open
Objective: The aim of the study was to evaluate the teratogenic effect of Nilavembu Kudineer (NVK) by testing in zebrafish embryo (Danio rerio).
Methods: The study consisted of 30 embryos/culture plate/dose concentration containing a seri…
View article: Bone Remodeling Around Photochemical Fortified-calcium Silicate Implants in Long Term Rabbit Femur Model
Bone Remodeling Around Photochemical Fortified-calcium Silicate Implants in Long Term Rabbit Femur Model Open
Calcium silicates have been used for a long time as bone grafting and regenerative material. Advent of nano sized calcium silicate has impacted tissue engineers, leading to preparation of several composites. Delivery of growth factors play…
View article: In-vitro Screening for Acetylcholinesterase enzyme Inhibition potential and Antioxidant Activity of Extracts of Ipomoea Aquatica Forsk: Therapeutic lead for Alzheimer's disease
In-vitro Screening for Acetylcholinesterase enzyme Inhibition potential and Antioxidant Activity of Extracts of Ipomoea Aquatica Forsk: Therapeutic lead for Alzheimer's disease Open
Two-phase extraction, characterization, and biological evaluation of chitin and chitosan from Rhizopus oryzaeDhanashree B. Gachhi, Basavaraj S. Hungund