Sushil Kumar
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View article: Indian Journal of Neurosurgery
Indian Journal of Neurosurgery Open
View article: Isolated Rapidly Progressive Interstitial Lung Disease Without Muscle or Skin Involvement in Idiopathic Inflammatory Myopathy: An Unusual Anti-Mi-2 Antibody Phenotype
Isolated Rapidly Progressive Interstitial Lung Disease Without Muscle or Skin Involvement in Idiopathic Inflammatory Myopathy: An Unusual Anti-Mi-2 Antibody Phenotype Open
View article: Effectiveness of Different Hand Sanitizers against the Communicable Diseases Causing Bacteria Isolated from the Hand Surface of Different Community People
Effectiveness of Different Hand Sanitizers against the Communicable Diseases Causing Bacteria Isolated from the Hand Surface of Different Community People Open
BACKGROUND: Hands serve as the essential source of germ transmission and considered as the foremost infectious portion of the body; therefore, hand cleanliness is extremely significant to diminish the growth of microbes. METHODS: The sampl…
View article: Effect of Distal Fragment Length on Construct Stability in an Extra-articular Distal Tibial Fracture Model Fixed With Locked Intramedullary Nailing: A Biomechanical Study
Effect of Distal Fragment Length on Construct Stability in an Extra-articular Distal Tibial Fracture Model Fixed With Locked Intramedullary Nailing: A Biomechanical Study Open
Introduction Fractures of the distal tibia are complex injuries with high complication rates, which include delayed union, non-union, and wound complications like dehiscence and infection. The two commonly employed definite internal fixati…
View article: Validation of stay-green and stem reserve mobilization QTLs: physiological and gene expression approach
Validation of stay-green and stem reserve mobilization QTLs: physiological and gene expression approach Open
Introduction Abiotic stress significantly reduces the wheat yield by hindering several physiological processes in plant. Stay-green (SG) and stem reserve mobilization (SRM) are the two key physiological traits, which can contribute signifi…
View article: Neuroprotective Activity of Amaranthus tricolor Leaves Extract for Haloperidol Induce Catalepsy by Behavior Method
Neuroprotective Activity of Amaranthus tricolor Leaves Extract for Haloperidol Induce Catalepsy by Behavior Method Open
View article: Pterostilbene Targets Hallmarks of Aging in the Gene Expression Landscape in Blood of Healthy Rats
Pterostilbene Targets Hallmarks of Aging in the Gene Expression Landscape in Blood of Healthy Rats Open
Scope Polyphenols from the phytoestrogen group, including pterostilbene (PTS), are known for their antioxidant, anti‐inflammatory, and anti‐cancer effects. In recent reports, phytoestrogens attenuate age‐related diseases; however, their pr…
View article: Honokiol and Nicotinamide Adenine Dinucleotide Improve Exercise Endurance in Pulmonary Hypertensive Rats Through Increasing SIRT3 Function in Skeletal Muscle
Honokiol and Nicotinamide Adenine Dinucleotide Improve Exercise Endurance in Pulmonary Hypertensive Rats Through Increasing SIRT3 Function in Skeletal Muscle Open
Pulmonary hypertension (PH) significantly impairs exercise capacity and the quality of life in patients, which is influenced by dysfunctions in multiple organ systems, including the right ventricle, lungs, and skeletal muscles. Recent rese…
View article: Beyond the white coat: Addressing safety challenges faced by women in medicine
Beyond the white coat: Addressing safety challenges faced by women in medicine Open
View article: Applications of ultrasonography imaging techniques in different aspects of bovine reproduction
Applications of ultrasonography imaging techniques in different aspects of bovine reproduction Open
View article: Classical dendritic cells contribute to hypoxia‐induced pulmonary hypertension
Classical dendritic cells contribute to hypoxia‐induced pulmonary hypertension Open
Pulmonary hypertension (PH) is a chronic and progressive disease with significant morbidity and mortality. It is characterized by remodeled pulmonary vessels associated with perivascular and intravascular accumulation of inflammatory cells…
View article: Interstitial macrophage phenotypes in Schistosoma-induced pulmonary hypertension
Interstitial macrophage phenotypes in Schistosoma-induced pulmonary hypertension Open
Background Schistosomiasis is a common cause of pulmonary hypertension (PH) worldwide. Type 2 inflammation contributes to the development of Schistosoma-induced PH. Specifically, interstitial macrophages (IMs) derived from monocytes play a…
View article: Single cell transcriptomic analyses reveal diverse and dynamic changes of distinct populations of lung interstitial macrophages in hypoxia-induced pulmonary hypertension
Single cell transcriptomic analyses reveal diverse and dynamic changes of distinct populations of lung interstitial macrophages in hypoxia-induced pulmonary hypertension Open
Introduction Hypoxia is a common pathological driver contributing to various forms of pulmonary vascular diseases leading to pulmonary hypertension (PH). Pulmonary interstitial macrophages (IMs) play pivotal roles in immune and vascular dy…
View article: Sustainable Energy Practices: Analysis of Gases And Particulate Matter Emissions During Pyrolysis of Polymeric Layers of Waste Silicon Solar Panels for Recycling Process
Sustainable Energy Practices: Analysis of Gases And Particulate Matter Emissions During Pyrolysis of Polymeric Layers of Waste Silicon Solar Panels for Recycling Process Open
View article: Optimization and modification of sperm cells genomic DNA extraction protocol using Qiagen DNeasy® Blood & Tissue Kit for qPCR based sex validation techniques
Optimization and modification of sperm cells genomic DNA extraction protocol using Qiagen DNeasy® Blood & Tissue Kit for qPCR based sex validation techniques Open
View article: Evaluating Environmental Footprint Through Life Cycle Assessment: Laboratory-Scale Thermal and Chemical Processes for Silicon Solar Panel Waste Material Extraction
Evaluating Environmental Footprint Through Life Cycle Assessment: Laboratory-Scale Thermal and Chemical Processes for Silicon Solar Panel Waste Material Extraction Open
View article: COMPARATIVE STUDY OF BUPIVACAINE WITH DEXMEDETOMIDINE AND BUPIVACAINE ALONE IN SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK
COMPARATIVE STUDY OF BUPIVACAINE WITH DEXMEDETOMIDINE AND BUPIVACAINE ALONE IN SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK Open
Objective: The objective is to compare the efficacy of bupivacaine with dexmedetomidine and bupivacaine alone when used for supraclavicular brachial plexus block in patients undergoing upper limb surgeries. Methods: This was a comparative …
View article: Medical Specialization: Giving Unhappy Postgraduates a Second Chance
Medical Specialization: Giving Unhappy Postgraduates a Second Chance Open
BACKGROUND Over the years, it has been noticed that some students struggle to excel in a specific specialty after enrollment, leading to potential depression and a requirement for psychiatric assistance. On the contrary, once a student has…
View article: Revolutionizing healthcare by use of artificial intelligence in esophageal carcinoma – a narrative review
Revolutionizing healthcare by use of artificial intelligence in esophageal carcinoma – a narrative review Open
Esophageal cancer is a major cause of cancer-related mortality worldwide, with significant regional disparities. Early detection of precursor lesions is essential to improve patient outcomes. Artificial intelligence (AI) techniques, includ…
View article: SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension
SIRT3 Is a Critical Regulator of Mitochondrial Function of Fibroblasts in Pulmonary Hypertension Open
Pulmonary hypertension (PH) is a heterogeneous and life-threatening cardiopulmonary disorder in which mitochondrial dysfunction is believed to drive pathogenesis, although the underlying mechanisms remain unclear. To determine if abnormal …
View article: Characterizing the Spatiotemporal Transcriptomic Response of the Right Ventricle to Acute Pressure Overload
Characterizing the Spatiotemporal Transcriptomic Response of the Right Ventricle to Acute Pressure Overload Open
This study analyzed microarray data of right ventricular (RV) tissue from rats exposed to pulmonary embolism to understand the initial dynamic transcriptional response to mechanical stress and compare it with experimental pulmonary hyperte…
View article: Local Complement Contributes to Pathogenic Activation of Lung Endothelial Cells in SARS-CoV-2 Infection
Local Complement Contributes to Pathogenic Activation of Lung Endothelial Cells in SARS-CoV-2 Infection Open
Endothelial dysfunction and inflammation contribute to the vascular pathology of coronavirus disease (COVID-19). However, emerging evidence does not support direct infection of endothelial or other vascular wall cells, and thus inflammatio…
View article: Figure S3 from Clinical Response of Live-Attenuated, <i>Listeria monocytogenes</i> Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma
Figure S3 from Clinical Response of Live-Attenuated, <i>Listeria monocytogenes</i> Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma Open
Image cytometry gating strategy for multi-plex IHC analysis of mesothelioma biopsies
View article: Table S1 from Clinical Response of Live-Attenuated, <i>Listeria monocytogenes</i> Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma
Table S1 from Clinical Response of Live-Attenuated, <i>Listeria monocytogenes</i> Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma Open
Biomarkers utilized for defining immune cell lineages in IHC analysis
View article: Figure S1 from Clinical Response of Live-Attenuated, <i>Listeria monocytogenes</i> Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma
Figure S1 from Clinical Response of Live-Attenuated, <i>Listeria monocytogenes</i> Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma Open
Study design
View article: supplemental figure legend from Combined Antitumor Therapy with Metronomic Topotecan and Hypoxia-Activated Prodrug, Evofosfamide, in Neuroblastoma and Rhabdomyosarcoma Preclinical Models
supplemental figure legend from Combined Antitumor Therapy with Metronomic Topotecan and Hypoxia-Activated Prodrug, Evofosfamide, in Neuroblastoma and Rhabdomyosarcoma Preclinical Models Open
supplemental figure legend
View article: Figure S2 from Clinical Response of Live-Attenuated, <i>Listeria monocytogenes</i> Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma
Figure S2 from Clinical Response of Live-Attenuated, <i>Listeria monocytogenes</i> Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma Open
Intratumoral leukocyte composition of mesothelioma representing pre- and post-therapy immunotherapy, evaluated by multiplex IHC.
View article: Supplementary Table 1 from Nab-Paclitaxel Is an Active Drug in Preclinical Model of Pediatric Solid Tumors
Supplementary Table 1 from Nab-Paclitaxel Is an Active Drug in Preclinical Model of Pediatric Solid Tumors Open
Supplementary Table 1 - PDF file 55K, Maximum tumor response achieved in rhabdomyosarcoma and neuroblastoma xenograft tumor models
View article: Figure S7 from CXCR3 and Cognate Ligands are Associated with Immune Cell Alteration and Aggressiveness of Pancreatic Ductal Adenocarcinoma
Figure S7 from CXCR3 and Cognate Ligands are Associated with Immune Cell Alteration and Aggressiveness of Pancreatic Ductal Adenocarcinoma Open
CIBERSORT analysis of micrarray data by CXCR3 and its ligands expression.
View article: Supplementary Data from Axl and Mertk Receptors Cooperate to Promote Breast Cancer Progression by Combined Oncogenic Signaling and Evasion of Host Antitumor Immunity
Supplementary Data from Axl and Mertk Receptors Cooperate to Promote Breast Cancer Progression by Combined Oncogenic Signaling and Evasion of Host Antitumor Immunity Open
Figure S1-S6