Dabeeran Zehra
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View article: Effect of azithromycin-conjugated gold and silver nanoparticles on thecytotoxicity of hepatocellular cancer cells
Effect of azithromycin-conjugated gold and silver nanoparticles on thecytotoxicity of hepatocellular cancer cells Open
Azithromycin is a member of macrolide antibiotics, and has been reported to inhibit the proliferation of cancer cells. Nanoparticles particularly nanometals have been recently investigated in cancer chemotherapy owing to their enhanced pha…
View article: COMPARATIVE THERAPEUTIC POTENTIAL OF ANTIBIOTIC LOADED GOLD AND SILVER NANOCONJUGATES IN CANCER THERAPY
COMPARATIVE THERAPEUTIC POTENTIAL OF ANTIBIOTIC LOADED GOLD AND SILVER NANOCONJUGATES IN CANCER THERAPY Open
Background: Nanomedicine is believed to be an emerging field to improve the efficacy of conventional chemotherapy. Nanoparticles (NPs), particularly drugs conjugated nanometals, have garnered attention as distinct drug carriers in terms of…
View article: Effects of Oral Iron Supplements in Pregnancy with IDA in Association with Oxidative Stress
Effects of Oral Iron Supplements in Pregnancy with IDA in Association with Oxidative Stress Open
Background: Iron deficiency anemia (IDA) is associated with adverse outcomes related to hemoglobin (Hb) and red cell indices and is now recognized as a major contributor to oxidative stress (OS). Maternal IDA during pregnancy is one of the…
View article: Predictors of Outcome in Management of Ruptured Arteriovenous Fistula in Hemodialysis Patients: A Cross-Sectional Study at a Tertiary Care Hospital, Karachi
Predictors of Outcome in Management of Ruptured Arteriovenous Fistula in Hemodialysis Patients: A Cross-Sectional Study at a Tertiary Care Hospital, Karachi Open
Bleeding from ruptured arteriovenous fistulae (AVF) is a distressing complication resulting from multiple factors and can lead to life-threatening hemorrhage. Objective: To analyze factors that contribute to the development of a bleeding r…
View article: Azithromycin as Potent Inhibitor of Cell Migration in Tumor Cell Line
Azithromycin as Potent Inhibitor of Cell Migration in Tumor Cell Line Open
Continuous obstacles behind the discovery of novel drugs for cancer therapy have necessitated the development of alternative strategy of drug repurposing—the development of old drugs for new therapeutic purposes. With an improved understan…
View article: The Allopurinol and Febuxostat in the Treatment of Hyperuricemic Patients and Their Impact on Lipid Fractions (Cholesterol, LDL, HDL)
The Allopurinol and Febuxostat in the Treatment of Hyperuricemic Patients and Their Impact on Lipid Fractions (Cholesterol, LDL, HDL) Open
Little is known about the role of serum uric acid and its impact on lipid fraction. The associations between hyperuricemia and much co-morbidity such as dyslipidemia and others are well recognized. This study aims to explore the impact of …
View article: Inhibitory Potential of Combination of Macrolide Antibiotic with Conventional Chemotherapeutic Agent Sorafenib on Growth Rate of Cancer Cell Population
Inhibitory Potential of Combination of Macrolide Antibiotic with Conventional Chemotherapeutic Agent Sorafenib on Growth Rate of Cancer Cell Population Open
Over the past few years great progress has been achieved in anticancer therapy, but development of resistance and unavoidable side effects have incapacitated these fulfilments. Keeping in view this demanding condition, numerous drugs with …
View article: Attitude and Practices Regarding Use of Direct Acting Antiviral Agents (DAAs) in the Treatment of Hepatitis C among Health Care Practitioners “A Survey-based Study”
Attitude and Practices Regarding Use of Direct Acting Antiviral Agents (DAAs) in the Treatment of Hepatitis C among Health Care Practitioners “A Survey-based Study” Open
Approximately 3% of the world population has been known to be infected with HCV. Hepatitis C virus is a major etiological factor behind the development of liver diseases such as cirrhosis and hepatocellular carcinoma. Interferon-based ther…
View article: Low Dose of Azithromycin Enhances the Anticancer Efficacy of Sorafenib in HepG2 Cell Line
Low Dose of Azithromycin Enhances the Anticancer Efficacy of Sorafenib in HepG2 Cell Line Open
Contribution ZM supervised the study.SU conceived the idea, designed the experiments and analyzed the data.AJ supervised the experiments.DZ performed the experiments, did statistical analysis and compiled the results.DZ wrote the manuscrip…
View article: Association of Depression, Anxiety and Stress in Medical Students Studying in Modular, Semester and Annual Examination System
Association of Depression, Anxiety and Stress in Medical Students Studying in Modular, Semester and Annual Examination System Open
Background: When there are high demands besides less resources, a person experiences a feeling of fear that is known as “Stress”. Students of professional schools/colleges and universities are encounter more stress than the general populat…
View article: Antitumor Potential of Antimicrobials: An Anticipated Armour for Hepatocellular Carcinoma
Antitumor Potential of Antimicrobials: An Anticipated Armour for Hepatocellular Carcinoma Open
Hepatocellular carcinoma also known as hepatoma is considered as the most common type of primary liver malignancy and is the leading cause of death worldwide. The incidence and mortality is still on the rise despite the drastic progress in…
View article: Prevalence of PCOS with Associated Symptoms and Complications at Tertiary Care Hospital of Karachi
Prevalence of PCOS with Associated Symptoms and Complications at Tertiary Care Hospital of Karachi Open
Aim: The aim of this study is to determine the prevalence of PCOS among different gynecological disorders at tertiary care hospital of Karachi and to assess the most frequent presenting complaint with associated complications among them.
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