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View article: ADAMTS13 in Bothrops lanceolatus snakebite envenoming: Crude venom-induced reduction of in vitro enzymatic activity and clinical correlation in snakebite patients
ADAMTS13 in Bothrops lanceolatus snakebite envenoming: Crude venom-induced reduction of in vitro enzymatic activity and clinical correlation in snakebite patients Open
Background Envenoming by Bothrops lanceolatus , a viperid endemic to Martinique an island in the Lesser Antilles, induces a unique clinical manifestation, i.e., thrombosis. Pathophysiological signaling leading to thrombotic events remains …
View article: Thromboinflammatory complications of Bothrops snakebite envenoming: the case of B. lanceolatus endemic to the Caribbean Island of Martinique
Thromboinflammatory complications of Bothrops snakebite envenoming: the case of B. lanceolatus endemic to the Caribbean Island of Martinique Open
Snakebite envenoming remains a predominant neglected disease in tropical and subtropical regions, with high rates of morbidity and mortality worldwide. Bothrops snakebite envenoming. is characterized by severe injuries at the site of venom…
View article: Real-World Data from the First Intracranial Aneurysm Cohort in the Eastern Caribbean from 2021 to 2024: The Population Characteristics, Treatment Outcomes, and Effectiveness of the Newly Established Regional Organization with Air Transfer to the First Tertiary Neurointerventional Center in the Eastern Caribbean
Real-World Data from the First Intracranial Aneurysm Cohort in the Eastern Caribbean from 2021 to 2024: The Population Characteristics, Treatment Outcomes, and Effectiveness of the Newly Established Regional Organization with Air Transfer to the First Tertiary Neurointerventional Center in the Eastern Caribbean Open
Background/Objectives: The establishment of the first tertiary Neurointerventional Center at the University Hospital of Martinique in 2021, with full coverage of the populations of the French Antilles and Guyana, represents a paradigm shif…
View article: Chlordecone (kepone) induces mitochondrial dysfunction in human cardiac tissue
Chlordecone (kepone) induces mitochondrial dysfunction in human cardiac tissue Open
Chlordecone exposure in humans has been associated with increased incidence of prostate cancer, impaired fertility, and fetal/perinatal abnormalities while experiment rodent studies suggest that chlordecone can inhibit magnesium-ATPase, li…
View article: Effectiveness of late and very late antivenom administration on recovery from snakebite-induced coagulopathy in French Guiana: a population-based study
Effectiveness of late and very late antivenom administration on recovery from snakebite-induced coagulopathy in French Guiana: a population-based study Open
No funding.
View article: Outcome from out-of-hospital cardiac arrest managed by the pre-hospital emergency medical system in Martinique, a French Caribbean Overseas Territory
Outcome from out-of-hospital cardiac arrest managed by the pre-hospital emergency medical system in Martinique, a French Caribbean Overseas Territory Open
The overall adult OHCA survival rate and survival with good neurological status on day-30 in the French Caribbean island of Martinique are low. OHCA survival rate may be improved by educating the population on basic life support techniques…
View article: Sargassum Inundations and the Risk of Hypertension Disorders Among Pregnant Women Living in the French Caribbean Island of Martinique
Sargassum Inundations and the Risk of Hypertension Disorders Among Pregnant Women Living in the French Caribbean Island of Martinique Open
Since 2011, Caribbean territories have experienced massive and repeated sargassum seaweed inundations. Once on shore, sargassum degradation through anaerobic metabolism elicits the release of many noxious molecules, including hydrogen sulf…
View article: Case Report: Acute myocarditis and cerebral infarction following Bothrops lanceolatus envenomation in Martinique: a case series
Case Report: Acute myocarditis and cerebral infarction following Bothrops lanceolatus envenomation in Martinique: a case series Open
Bothrops lanceolatus (Bl), a snake endemic to Martinique, is responsible for numerous envenomations annually, leading to severe complications such as thrombosis, necrosis, and hemorrhage. This case series investigates the link between Both…
View article: A murine experimental model of the pulmonary thrombotic effect induced by the venom of the snake Bothrops lanceolatus
A murine experimental model of the pulmonary thrombotic effect induced by the venom of the snake Bothrops lanceolatus Open
Background The venom of Bothrops lanceolatus , a viperid species endemic to the Lesser Antillean Island of Martinique, induces thrombosis in a number of patients. Previous clinical observations indicate that thrombotic events are more comm…
View article: The Contrasting Effects of Bothrops lanceolatus and Bothrops atrox Venom on Procoagulant Activity and Thrombus Stability under Blood Flow Conditions
The Contrasting Effects of Bothrops lanceolatus and Bothrops atrox Venom on Procoagulant Activity and Thrombus Stability under Blood Flow Conditions Open
Background: Consumption coagulopathy and hemorrhagic syndrome are the typical features of Bothrops sp. snake envenoming. In contrast, B. lanceolatus envenoming can induce thrombotic complications. Our aim was to test whether crude B. lance…
View article: Sex-related differences in toxic manifestations induced by Bothrops atrox venom in mice
Sex-related differences in toxic manifestations induced by Bothrops atrox venom in mice Open
Lancehead snakes of the genus Bothrops are responsible for 90% of the snakebites in Latin America. The objective of this study was to assess the LD50, physical, and hematological manifestations induced by B. atrox venom in male …
View article: Bothrops lanceolatus Envenoming in Martinique: A Historical Perspective of the Clinical Effectiveness of Bothrofav Antivenom Treatment
Bothrops lanceolatus Envenoming in Martinique: A Historical Perspective of the Clinical Effectiveness of Bothrofav Antivenom Treatment Open
Bothrofav, a monospecific antivenom, was introduced in June 1991 and has shown excellent effectiveness against life-threatening and thrombotic complications of Bothrops lanceolatus envenoming. Because of the reoccurrence of cerebral stroke…
View article: Clinical and Epidemiological Characteristics of Severe Acute Adult Poisonings in French Amazonia: Urgent Need for a Toxicovigilance Monitoring Framework
Clinical and Epidemiological Characteristics of Severe Acute Adult Poisonings in French Amazonia: Urgent Need for a Toxicovigilance Monitoring Framework Open
Background: Acute poisonings (AP) are a significant public health problem, accounting for a high number of emergency department visits and thousands of deaths worldwide. This study aimed to assess the epidemiology of AP in an adult populat…
View article: Mortality Trend of Severe COVID-19 in Under-Vaccinated Population Admitted to ICU in French Amazonia
Mortality Trend of Severe COVID-19 in Under-Vaccinated Population Admitted to ICU in French Amazonia Open
(1) Background: Until December 2021, French Guiana (FG), located in South America, faced four consecutive COVID-19 epidemic waves. This study sought to analyze the mortality trend of severe COVID-19 patients admitted to the referral ICU of…
View article: Mortality Trend of Severe COVID-19 in Under-Vaccinated Population Admitted to ICU in French Amazonia
Mortality Trend of Severe COVID-19 in Under-Vaccinated Population Admitted to ICU in French Amazonia Open
(1) Background: Until December 2021, French Guiana (FG), located in South America, faced four consecutive COVID-19 epidemic waves. This study sought to analyze the mortality trend of severe COVID-19 patients admitted to the referral ICU of…
View article: Review of: "Human health effects of volcanic eruptions – a systematic review"
Review of: "Human health effects of volcanic eruptions – a systematic review" Open
I appreciate the opportunity to review this comprehensive study on the human health effects of volcanic eruptions, presented as a systematic review.The authors have excelled in presenting a well-organized and clearly articulated body of wo…
View article: Increased Binding of von Willebrand Factor to Sub-Endothelial Collagen May Facilitate Thrombotic Events Complicating Bothrops lanceolatus Envenomation in Humans
Increased Binding of von Willebrand Factor to Sub-Endothelial Collagen May Facilitate Thrombotic Events Complicating Bothrops lanceolatus Envenomation in Humans Open
Consumption coagulopathy and hemorrhagic syndrome exacerbated by blood anticoagulability remain the most important causes of lethality associated with Bothrops snake envenomation. Bothrops venom also engages platelet aggregation on the inj…
View article: Effect of the time to antivenom administration on recovery from snakebite envenoming-related coagulopathy in French Guiana
Effect of the time to antivenom administration on recovery from snakebite envenoming-related coagulopathy in French Guiana Open
Background Snakebite (SB) envenoming is an acute emergency requiring an early care delivery. We aimed to search for the time to reach healthcare facilities in various regions of French Guiana (FG) and to assess the impact of time to antive…
View article: Early Discharge, Outpatient Evaluation, and Home Management of Acute Respiratory Failure from COVID-19 in Martinique
Early Discharge, Outpatient Evaluation, and Home Management of Acute Respiratory Failure from COVID-19 in Martinique Open
A worldwide pandemic of viral infection due to SARS-CoV-2 (and its resultant disease, COVID-19) has been ongoing since 2019. Martinique was affected by a major wave in summer 2021, with saturation of the health system forcing the implement…
View article: Antimicrobial Susceptibility of Community-Acquired Urine Bacterial Isolates in French Amazonia
Antimicrobial Susceptibility of Community-Acquired Urine Bacterial Isolates in French Amazonia Open
Bacterial resistance in community-acquired urinary tract infections (UTIs) is increasing worldwide. Our study aimed to assess the microbiological epidemiology and antimicrobial susceptibility patterns of community-acquired urine bacterial …
View article: Sargassum seaweed in the Caribbean: A major public health problem still unsolved
Sargassum seaweed in the Caribbean: A major public health problem still unsolved Open
International audience
View article: Bothrops (Fer-de-lance) snakebites in the French departments of the Americas (Martinique and Guyana): Clinical and experimental studies and treatment by immunotherapy
Bothrops (Fer-de-lance) snakebites in the French departments of the Americas (Martinique and Guyana): Clinical and experimental studies and treatment by immunotherapy Open
Snakebite envenomation is a relevant medical hazard in French Guiana and Martinique, two French territories in the Americas. All snakebite envenomations in Martinique are inflicted by the endemic viperid species Bothrops lanceolatus , wher…
View article: Inflammation and Oxidative Stress in Snakebite Envenomation: A Brief Descriptive Review and Clinical Implications
Inflammation and Oxidative Stress in Snakebite Envenomation: A Brief Descriptive Review and Clinical Implications Open
Snakebite envenoming is a pathological condition which may occur in response to the injection of venom. Snake venoms contain a complex mixture of biologically active molecules which are responsible for a broad spectrum of clinical manifest…
View article: French Scorpionism (Mainland and Oversea Territories): Narrative Review of Scorpion Species, Scorpion Venom, and Envenoming Management
French Scorpionism (Mainland and Oversea Territories): Narrative Review of Scorpion Species, Scorpion Venom, and Envenoming Management Open
Sixty-seven scorpion species have been described in France and its territories, where they have been found to be heterogeneously distributed. Indeed, only one species can be found on Réunion Island, while 38 species exist in French Guiana.…
View article: Acute Rubigine® Poisoning in Martinique a French Overseas Department of America: Clinical Characteristics and Prognostic Factors
Acute Rubigine® Poisoning in Martinique a French Overseas Department of America: Clinical Characteristics and Prognostic Factors Open
Rubigine® is an anti-rust stain remover containing fluorides which is believed to have been the cause of many deaths in Martinique. However, after the modification of its composition in 2006, serious poisoning from old formulas containing …
View article: Clinical Characteristics of Ciguatera Poisoning in Martinique, French West Indies—A Case Series
Clinical Characteristics of Ciguatera Poisoning in Martinique, French West Indies—A Case Series Open
Ciguatera poisoning (CP) is one of the most common causes worldwide of marine poisoning associated with fish consumption from tropical areas. Its incidence is underreported. CP cases seem to increase with grouped cases reported during summ…
View article: Risk of preeclampsia among women living in coastal areas impacted by sargassum strandings on the French Caribbean island of Martinique
Risk of preeclampsia among women living in coastal areas impacted by sargassum strandings on the French Caribbean island of Martinique Open
View article: Clinical Characteristics of Ciguatera Fish Poisoning in Martinique, French West Indies – A Case Series
Clinical Characteristics of Ciguatera Fish Poisoning in Martinique, French West Indies – A Case Series Open
Ciguatera fish poisoning (CFP) is one of the most common causes worldwide of marine poisoning associated with fish consumption from tropical areas. Its incidence is underreported. CFP cases seem to increase with grouped cases reported duri…
View article: Characteristics of Snakebite-Related Infection in French Guiana
Characteristics of Snakebite-Related Infection in French Guiana Open
Wound infection is frequently reported following snakebite (SB). This study is retrospective. It was conducted in the emergency department and the Intensive Care Unit (ICU) of Cayenne General Hospital between 1 January 2016 and 31 July 202…
View article: COVID-19 Outbreak: Burnout and Posttraumatic Stress Disorder, a Harmful Chronology for Health Caregivers in Emergency Departments and Intensive Care Units
COVID-19 Outbreak: Burnout and Posttraumatic Stress Disorder, a Harmful Chronology for Health Caregivers in Emergency Departments and Intensive Care Units Open
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