Dafa Shi
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View article: Mapping Resting‐State Brain Functional Specialization to Neurotransmitter Profiles in Autism Spectrum Disorder
Mapping Resting‐State Brain Functional Specialization to Neurotransmitter Profiles in Autism Spectrum Disorder Open
Background Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder. However, its diagnosis and effective treatment present challenges. Understanding neurotransmitter impairments may offer new perspectives into the …
View article: ADVANCED MR TECHNIQUES IN MRI-NEGATIVE TEMPORAL LOBE EPILEPSY
ADVANCED MR TECHNIQUES IN MRI-NEGATIVE TEMPORAL LOBE EPILEPSY Open
Temporal lobe epilepsy (TLE) is the most prevalent type of epilepsy worldwide. However, up to 30% of TLE cases have negative/nonlesional magnetic resonance imaging (MRI) results. Identifying biomarkers for MRI-negative TLE is crucial for e…
View article: Multimodal data fusion reveals functional and neurochemical correlates of Parkinson's disease
Multimodal data fusion reveals functional and neurochemical correlates of Parkinson's disease Open
Our results revealed abnormal brain activity patterns and specific neurotransmitter deficits in patients with PD, which may provide new insights into the mechanisms and potential targets for pharmacotherapy.
View article: Clinical Breast <scp>MRI</scp>‐based Radiomics for Distinguishing Benign and Malignant Lesions: An Analysis of Sequences and Enhanced Phases
Clinical Breast <span>MRI</span>‐based Radiomics for Distinguishing Benign and Malignant Lesions: An Analysis of Sequences and Enhanced Phases Open
Background Previous studies have used different imaging sequences and different enhanced phases for breast lesion calsification in radiomics. The optimal sequence and contrast enhanced phase is unclear. Purpose To identify the optimal magn…
View article: Protective effects of SS-31 on Post-Contrast Acute Kidney Injury in Diabetes Mice
Protective effects of SS-31 on Post-Contrast Acute Kidney Injury in Diabetes Mice Open
Post-contrast acute kidney injury (PC-AKI) has emerged as the third leading cause of iatrogenic acute renal failure. Diabetes mellitus not only represents an independent risk factor for PC-AKI but also remains a major cause of chronic kidn…
View article: Amplitude of low-frequency fluctuation-based regional radiomics similarity network: Biomarker for Parkinson’s disease
Amplitude of low-frequency fluctuation-based regional radiomics similarity network: Biomarker for Parkinson’s disease Open
Parkinson's disease (PD) is a highly heterogeneous disorder that is difficult to diagnose. Therefore, reliable biomarkers are needed. We implemented a method constructing a regional radiomics similarity network (R2SN) based on the amplitud…
View article: Neuroimaging biomarkers for detecting schizophrenia: A resting-state functional MRI-based radiomics analysis
Neuroimaging biomarkers for detecting schizophrenia: A resting-state functional MRI-based radiomics analysis Open
Schizophrenia (SZ) is a common psychiatric disorder that is difficult to accurately diagnose in clinical practice. Quantifiable biomarkers are urgently required to explore the potential physiological mechanism of SZ and improve its diagnos…
View article: Radiomics Based on Digital Mammography Helps to Identify Mammographic Masses Suspicious for Cancer
Radiomics Based on Digital Mammography Helps to Identify Mammographic Masses Suspicious for Cancer Open
Objectives This study aims to build radiomics model of Breast Imaging Reporting and Data System (BI-RADS) category 4 and 5 mammographic masses extracted from digital mammography (DM) for mammographic masses characterization by using a sens…
View article: Machine Learning for Detecting Parkinson’s Disease by Resting-State Functional Magnetic Resonance Imaging: A Multicenter Radiomics Analysis
Machine Learning for Detecting Parkinson’s Disease by Resting-State Functional Magnetic Resonance Imaging: A Multicenter Radiomics Analysis Open
Parkinson’s disease (PD) is one of the most common progressive degenerative diseases, and its diagnosis is challenging on clinical grounds. Clinically, effective and quantifiable biomarkers to detect PD are urgently needed. In our study, w…
View article: Magnetic Resonance Imaging of Contrast-Induced Acute Renal Injury and Related Pathological Alterations In Vivo
Magnetic Resonance Imaging of Contrast-Induced Acute Renal Injury and Related Pathological Alterations In Vivo Open
Background. The definitive mechanisms of CI-AKI include contrast medium (CM) nephrotoxicity and CM disturbances in renal blood flow, but how the immune system responds to CM has rarely been mentioned in previous studies, and different cell…
View article: Gadolinium Retention in the Brain of Mother and Pup Mouse: Effect of Pregnancy and Repeated Administration of <scp>Gadolinium‐Based</scp> Contrast Agents
Gadolinium Retention in the Brain of Mother and Pup Mouse: Effect of Pregnancy and Repeated Administration of <span>Gadolinium‐Based</span> Contrast Agents Open
Background The association of repeated administration of gadolinium‐based contrast agents (GBCAs) with the gadolinium (Gd) retention in the brains of mother and fetus remains unclear. Purpose To investigate the effects of pregnancy and rep…
View article: The Application of Functional Magnetic Resonance Imaging in Type 2 Diabetes Rats With Contrast-Induced Acute Kidney Injury and the Associated Innate Immune Response
The Application of Functional Magnetic Resonance Imaging in Type 2 Diabetes Rats With Contrast-Induced Acute Kidney Injury and the Associated Innate Immune Response Open
Aims Contrast-induced acute kidney injury (CI-AKI) is the third most common in-hospital acquired AKI, and its mechanism is not fully clear. Its morbidity increases among populations with chronic kidney disease (CKD), older age, diabetes me…
View article: Machine Learning of Schizophrenia Detection with Structural and Functional Neuroimaging
Machine Learning of Schizophrenia Detection with Structural and Functional Neuroimaging Open
Schizophrenia (SZ) is a severe psychiatric illness, and it affects around 1% of the general population; however, its reliable diagnosis is challenging. Functional MRI (fMRI) and structural MRI (sMRI) are useful techniques for investigating…
View article: Neuroprotective and Angiogenesis Effects of Levetiracetam Following Ischemic Stroke in Rats
Neuroprotective and Angiogenesis Effects of Levetiracetam Following Ischemic Stroke in Rats Open
Objective: The present study explored whether levetiracetam (LEV) could protect against experimental brain ischemia and enhance angiogenesis in rats, and investigated the potential mechanisms in vivo and in vitro . Methods: The middle cere…
View article: Application of Functional Magnetic Resonance Imaging in the Diagnosis of Parkinson’s Disease: A Histogram Analysis
Application of Functional Magnetic Resonance Imaging in the Diagnosis of Parkinson’s Disease: A Histogram Analysis Open
This study aimed to investigate the value of amplitude of low-frequency fluctuation (ALFF)-based histogram analysis in the diagnosis of Parkinson’s disease (PD) and to investigate the regions of the most important discriminative features a…