Dagmar S. Trachsel
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View article: Preliminary assessment of the leukocyte coping capacity as a point of care marker in horses with stress associated diseases
Preliminary assessment of the leukocyte coping capacity as a point of care marker in horses with stress associated diseases Open
Lame horses had higher EGUS scores and lower LCC levels, indicating a possible link between lameness, EGUS, and stress. Our findings support further investigation into the use of LCC as a quantitative immunological marker of stress with st…
View article: Charting the equine miRNA landscape: An integrated pipeline and browser for annotating, quantifying, and visualizing expression
Charting the equine miRNA landscape: An integrated pipeline and browser for annotating, quantifying, and visualizing expression Open
MicroRNAs (miRNAs) are essential regulators of gene expression, yet few comprehensive databases exist for miRNA expression in non-model species, limiting our ability to characterize their roles in gene regulation, development, and disease.…
View article: Severe Neurologic Disease in a Horse Caused by Tick-Borne Encephalitis Virus, Austria, 2021
Severe Neurologic Disease in a Horse Caused by Tick-Borne Encephalitis Virus, Austria, 2021 Open
As evidenced by sero-epidemiological studies, infections of horses with the tick-borne encephalitis virus (TBEV) occur frequently in TBEV-endemic areas. However, there are only very few reports of clinical cases. A possible underreporting …
View article: Multilineage Differentiation Potential of Equine Adipose-Derived Stromal/Stem Cells from Different Sources
Multilineage Differentiation Potential of Equine Adipose-Derived Stromal/Stem Cells from Different Sources Open
The investigation of multipotent stem/stromal cells (MSCs) in vitro represents an important basis for translational studies in large animal models. The study’s aim was to examine and compare clinically relevant in vitro properties of equin…
View article: Comparison of Sources and Methods for the Isolation of Equine Adipose Tissue-Derived Stromal/Stem Cells and Preliminary Results on Their Reaction to Incubation with 5-Azacytidine
Comparison of Sources and Methods for the Isolation of Equine Adipose Tissue-Derived Stromal/Stem Cells and Preliminary Results on Their Reaction to Incubation with 5-Azacytidine Open
Physiological particularities of the equine heart justify the development of an in vitro model suitable for investigations of the species-specific equine cardiac electrophysiology. Adipose tissue-derived stromal/stem cells (ASCs) could be …
View article: Long-read RNA Sequencing Improves the Annotation of the Equine Transcriptome
Long-read RNA Sequencing Improves the Annotation of the Equine Transcriptome Open
1 Abstract A high-quality reference genome assembly, a biobank of diverse equine tissues from the Functional Annotation of the Animal Genome (FAANG) initiative, and incorporation of long-read sequencing technologies, have enabled efforts t…
View article: Seroepidemiological Survey of West Nile Virus Infections in Horses from Berlin/Brandenburg and North Rhine-Westphalia, Germany
Seroepidemiological Survey of West Nile Virus Infections in Horses from Berlin/Brandenburg and North Rhine-Westphalia, Germany Open
Following the introduction of the West Nile virus (WNV) into eastern Germany in 2018, increasing infections have been diagnosed in birds, equines, and humans over time, while the spread of WNV into western Germany remained unclear. We scre…
View article: Preliminary assessment of left ventricular function by tissue Doppler imaging and two-dimensional speckle tracking echocardiography in horses with equine metabolic syndrome
Preliminary assessment of left ventricular function by tissue Doppler imaging and two-dimensional speckle tracking echocardiography in horses with equine metabolic syndrome Open
The equine metabolic syndrome (EMS) has many parallels to the human metabolic syndrome (HMS).The HMS predisposes to cardiovascular diseases.Standard echocardiographic exams showed few abnormalities in HMS and advanced echocardiographic tec…
View article: Success of treatment comparing two omeprazole preparations for Equine Gastric Ulcer Syndrome (EGUS)
Success of treatment comparing two omeprazole preparations for Equine Gastric Ulcer Syndrome (EGUS) Open
Zusammenfassung: Das Equine Gastric Ulcer Syndrome (EGUS) ist ein häufiges Problem bei Sportpferden.Im Consensus Statement des European College of Equine Internal Medicine (ECEIM) sowie von den Herstellern wird Omeprazol in einer Dosierung…
View article: Treatment Decisions in Children With Asthma in a Real-Life Clinical Setting: The Swiss Paediatric Airway Cohort
Treatment Decisions in Children With Asthma in a Real-Life Clinical Setting: The Swiss Paediatric Airway Cohort Open
View article: Preliminary study on the effects of pergolide on left ventricular function in the horses with pituitary pars intermedia dysfunction
Preliminary study on the effects of pergolide on left ventricular function in the horses with pituitary pars intermedia dysfunction Open
Background: Pituitary pars intermedia dysfunction (PPID), a neurodegenerative disease leading to reduced dopamine production, is a common disease in aged horses. The treatment is based on administration of the dopamine agonist pergolide. T…
View article: Effects of the equine metabolic syndrome (EMS) on the cardiac autonomic function and on the arterial blood pressure in the horse
Effects of the equine metabolic syndrome (EMS) on the cardiac autonomic function and on the arterial blood pressure in the horse Open
View article: Association between Disease Severity, Heart Rate Variability (HRV) and Serum Cortisol Concentrations in Horses with Acute Abdominal Pain
Association between Disease Severity, Heart Rate Variability (HRV) and Serum Cortisol Concentrations in Horses with Acute Abdominal Pain Open
Heart rate variability (HRV) is a noninvasive technique to detect changes in the autonomous nervous system. It has rarely been investigated in horses with colic. Therefore, the objective was to assess the evolution of HRV parameters and co…
View article: Effects of trimethoprim–sulfadiazine and detomidine on the function of equine K<sub>v</sub>11.1 channels in a two‐electrode voltage‐clamp (<scp>TEVC</scp>) oocyte model
Effects of trimethoprim–sulfadiazine and detomidine on the function of equine K<sub>v</sub>11.1 channels in a two‐electrode voltage‐clamp (<span>TEVC</span>) oocyte model Open
The long QT syndrome ( LQTS ) is a channelopathy that can lead to severe arrhythmia and sudden cardiac death. Pharmacologically induced LQTS is caused by interaction between drugs and potassium channels, especially the K v 11.1 channel. Du…
View article: Agreement between Electrocardiogram and Heart Rate Meter Is Low for the Measurement of Heart Rate Variability during Exercise in Young Endurance Horses
Agreement between Electrocardiogram and Heart Rate Meter Is Low for the Measurement of Heart Rate Variability during Exercise in Young Endurance Horses Open
Analysis of the heart rate variability (HRV) gains more and more importance in the assessment of training practice and welfare in equine industry. It relies on mathematical analyses of reliably and accurately measured variations in success…
View article: Molecular cloning and functional expression of the K + channel K V 7.1 and the regulatory subunit KCNE1 from equine myocardium
Molecular cloning and functional expression of the K + channel K V 7.1 and the regulatory subunit KCNE1 from equine myocardium Open
View article: Relationships between body dimensions, body weight, age, gender, breed and echocardiographic dimensions in young endurance horses
Relationships between body dimensions, body weight, age, gender, breed and echocardiographic dimensions in young endurance horses Open
View article: Differences in the electrocardiographic QT interval of various breeds of athletic horses during rest and exercise
Differences in the electrocardiographic QT interval of various breeds of athletic horses during rest and exercise Open
View article: Scientific Abstracts 7th Congress of the European College of Equine Internal Medicine
Scientific Abstracts 7th Congress of the European College of Equine Internal Medicine Open
Procalcitonin (PCT) seems to be an early marker of bacterial
\ninfection. The increase of its concentration is due to bacterial
\nendotoxin and inflammatory cytokines. In horses’ GI diseases,
\nhypersecretion of fluid, motility disturbance…