Dahong Yang
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View article: The role of insulin resistance in the longitudinal progression from NAFLD to cardiovascular-kidney-metabolic disease
The role of insulin resistance in the longitudinal progression from NAFLD to cardiovascular-kidney-metabolic disease Open
Insulin resistance independently accelerated the progression from NAFLD to CKM diseases, particularly ischemic stroke. Healthy sleep and regular physical activity failed to offset this detrimental impact.
View article: Relationship between ASPECTS-region and clinical outcome in patients with large vessel occlusion stroke: a post-hoc analysis of randomized clinical trial
Relationship between ASPECTS-region and clinical outcome in patients with large vessel occlusion stroke: a post-hoc analysis of randomized clinical trial Open
Background: The relationship between the infarct region and prognosis can assist clinicians in perioperative decision-making. However, the time (early or extended window) of the stroke may also influence the identification of prognosticall…
View article: Dual effects of digital technology on high quality development of road transportation in Heilongjiang Province China
Dual effects of digital technology on high quality development of road transportation in Heilongjiang Province China Open
View article: Association between occlusion site and clinical outcomes in patients with acute basilar artery occlusion
Association between occlusion site and clinical outcomes in patients with acute basilar artery occlusion Open
In patients treated with EVT, our findings showed that clinical outcomes significantly differed by occlusion site. Additionally, EVT demonstrated superior clinical effectiveness among 3 occlusion sites compared to SMT. These findings suppo…
View article: Effectiveness of collateral status on clinical outcomes in patients with established large infarct: a prospective cohort study
Effectiveness of collateral status on clinical outcomes in patients with established large infarct: a prospective cohort study Open
Background: The specific association of collateral status on outcomes in patients with large ischemic stroke (ASPECTS ≤ 5) remains unclear. This study aimed to investigate the association between collateral status and outcomes in patients …
View article: Intra-Arterial Tenecteplase Following Endovascular Reperfusion for Large Vessel Occlusion Acute Ischemic Stroke
Intra-Arterial Tenecteplase Following Endovascular Reperfusion for Large Vessel Occlusion Acute Ischemic Stroke Open
Importance The impact of adjunctive intra-arterial tenecteplase administration following near-complete to complete reperfusion by endovascular thrombectomy (EVT) for acute ischemic stroke is unknown. Objective To assess the efficacy and ad…
View article: Values of H-Type Hypertension in Patients with Large Vessel Occlusion
Values of H-Type Hypertension in Patients with Large Vessel Occlusion Open
Our findings suggest that patients with H-type hypertension have a lower likelihood of achieving favorable outcomes but do not have an increased mortality rate within 90 days.
View article: Effect of occlusion site on the effectiveness and safety of endovascular thrombectomy for large ischemic cores: A cohort study
Effect of occlusion site on the effectiveness and safety of endovascular thrombectomy for large ischemic cores: A cohort study Open
Background: Recent clinical trials have shown that patients with large ischemic cores have better outcomes with endovascular thrombectomy (EVT) compared with standard medical treatment (SMT) alone.We aim to assess whether the relationship …
View article: Adjunctive intra-arterial tenecteplase after successful endovascular thrombectomy in patients with large vessel occlusion stroke (POST-TNK): Study rationale and design
Adjunctive intra-arterial tenecteplase after successful endovascular thrombectomy in patients with large vessel occlusion stroke (POST-TNK): Study rationale and design Open
Rationale: Adjunct intra-arterial alteplase has been shown to potentially improve clinical outcomes in patients with large vessel occlusion (LVO) stroke who have undergone successful endovascular thrombectomy. Tenecteplase, known for its e…
View article: Adjunctive Intra-arterial Urokinase after Successful Endovascular Thrombectomy in Patients with Large Vessel Occlusion Stroke (POST-UK): Study protocol of a multicenter, prospective, randomized, open-label, blinded-endpoint trial
Adjunctive Intra-arterial Urokinase after Successful Endovascular Thrombectomy in Patients with Large Vessel Occlusion Stroke (POST-UK): Study protocol of a multicenter, prospective, randomized, open-label, blinded-endpoint trial Open
Background Intra-arterial infusion of an adjunctive thrombolytic agent after macrovascular recanalization by endovascular thrombectomy (EVT) was regarded as a promising strategy to promote outcomes of stroke patients. Given the characteris…
View article: True first‐pass effect in patients undergoing thrombectomy for acute large core strokes
True first‐pass effect in patients undergoing thrombectomy for acute large core strokes Open
Objective The impact of true first‐pass effect (T‐FPE, achieving substantial recanalization with extended thrombolysis in cerebral infarction; eTICI 3 after 1 thrombectomy) and outcomes on acute ischemic stroke (AIS) with large ischemic co…
View article: Corrigendum: Blood glucose to predict symptomatic intracranial hemorrhage after endovascular treatment of acute ischemic stroke with large infarct core: a prospective observational study
Corrigendum: Blood glucose to predict symptomatic intracranial hemorrhage after endovascular treatment of acute ischemic stroke with large infarct core: a prospective observational study Open
[This corrects the article DOI: 10.3389/fneur.2024.1367177.].
View article: Endovascular treatment versus standard medical treatment in patients with established large infarct: a cohort study
Endovascular treatment versus standard medical treatment in patients with established large infarct: a cohort study Open
Background: Previous trials confirmed the benefit of endovascular treatment (EVT) in acute large core stroke, but the effect of EVT on outcomes in these patients based on noncontrast computed tomography (NCCT) in real-world clinical practi…
View article: Endovascular Therapy and Outcomes Among Patients With Very Large Ischemic Core Stroke
Endovascular Therapy and Outcomes Among Patients With Very Large Ischemic Core Stroke Open
Importance The association of endovascular therapy (EVT) with outcomes is unclear for patients with very low Alberta Stroke Program Early Computed Tomography Score (ASPECTS) within 24 hours of stroke onset. Objective To explore the associa…
View article: Blood glucose to predict symptomatic intracranial hemorrhage after endovascular treatment of acute ischemic stroke with large infarct core: a prospective observational study
Blood glucose to predict symptomatic intracranial hemorrhage after endovascular treatment of acute ischemic stroke with large infarct core: a prospective observational study Open
Introduction Symptomatic intracranial hemorrhage (sICH) is a serious complication of acute ischemic stroke (AIS) after endovascular treatment (EVT). Limited data exist regarding predictors and clinical implications of sICH after EVT, under…
View article: MARVEL: A Randomized Double‐Blind, Placebo‐Controlled Trial in Patients Undergoing Endovascular Therapy: Study Rationale and Design
MARVEL: A Randomized Double‐Blind, Placebo‐Controlled Trial in Patients Undergoing Endovascular Therapy: Study Rationale and Design Open
Background Steroids have pleiotropic neuroprotective actions including the regulation of inflammation and apoptosis which may influence the effects of ischemia on neurons, glial cells, and blood vessels. The effect of low‐dose methylpredni…
View article: The impact of stress hyperglycemia ratio on short-term and long-term outcomes for acute basilar artery occlusion underwent endovascular treatment
The impact of stress hyperglycemia ratio on short-term and long-term outcomes for acute basilar artery occlusion underwent endovascular treatment Open
Background Stress hyperglycemia ratio (SHR) reflects a true acute hyperglycemic state during acute basilar artery occlusion (ABAO). We aimed to investigate the association between SHR and short-term and long-term outcomes in patients with …
View article: Intravenous tirofiban following successful reperfusion in intracranial large artery atherosclerotic stroke: A secondary analysis of a randomized clinical trial
Intravenous tirofiban following successful reperfusion in intracranial large artery atherosclerotic stroke: A secondary analysis of a randomized clinical trial Open
Objective This study aimed to investigate whether treatment with adjunct intravenous tirofiban is associated with improved outcomes following successful reperfusion in patients with intracranial atherosclerotic stroke. Methods Patients wit…
View article: Methylprednisolone as Adjunctive Therapy for Large Vessel Occlusion (MARVEL): a Randomized Double-blind, Placebo-controlled Trial in Patients undergoing Endovascular therapy: Study Rationale and Design
Methylprednisolone as Adjunctive Therapy for Large Vessel Occlusion (MARVEL): a Randomized Double-blind, Placebo-controlled Trial in Patients undergoing Endovascular therapy: Study Rationale and Design Open
Background Steroids have pleiotropic neuroprotective actions including the regulation of inflammation and apoptosis which may influence the effects of ischemia on neurons, glial cells, and blood vessels. The effect of low-dose methylpredni…
View article: Association between stress hyperglycemia and outcomes in patients with acute ischemic stroke due to large vessel occlusion
Association between stress hyperglycemia and outcomes in patients with acute ischemic stroke due to large vessel occlusion Open
Aims This study aimed to evaluate the association between stress hyperglycemia ratio (SHR) and clinical outcomes at 90 days in acute ischemic stroke due to large vessel occlusion receiving endovascular treatment. Methods The RESCUE BT tria…
View article: Predictors of Mechanical Thrombectomy for Anterior Circulation Emergent Large-Vessel Occlusion in the Older Adults
Predictors of Mechanical Thrombectomy for Anterior Circulation Emergent Large-Vessel Occlusion in the Older Adults Open
Few studies have reported the clinical outcomes of older adult patients with acute anterior circulation large-vessel occlusion (LVO) who underwent mechanical thrombectomy (MT). Therefore, we investigated the safety, functional outcomes, an…
View article: Prognostic value of net water uptake in acute ischemic stroke: a protocol for a systematic review and meta-analysis
Prognostic value of net water uptake in acute ischemic stroke: a protocol for a systematic review and meta-analysis Open
Review question / Objective: The purpose of this protocol is to present a transparent and clear methodology for performing a systematic review and meta-analysis of the available literature aimed to answer the following question: among pati…