Daisey Methorst
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View article: SMC Abca1 and Abcg1 Deficiency Enhances Urinary Bladder Distension but Not Atherosclerosis
SMC Abca1 and Abcg1 Deficiency Enhances Urinary Bladder Distension but Not Atherosclerosis Open
BACKGROUND: Smooth muscle cells (SMCs) regulate blood flow distribution via vasoconstriction mediated by α-ARs (α-adrenergic receptors). Plasma membrane cholesterol accumulation affects α 1 -AR signaling and promotes loss of SMC contractil…
View article: Human Plaque Myofibroblasts to Study Mechanisms of Atherosclerosis
Human Plaque Myofibroblasts to Study Mechanisms of Atherosclerosis Open
Background Plaque myofibroblasts are critical players in the initiation and advancement of atherosclerotic disease. They are involved in the production of extracellular matrix, the formation of the fibrous cap, and the underlying lipidic c…
View article: Human primary plaque cell cultures to study mechanisms of atherosclerosis
Human primary plaque cell cultures to study mechanisms of atherosclerosis Open
Plaque smooth muscle cells are critical players in the initiation and advancement of atherosclerotic disease. They produce extracellular matrix (ECM) components, which play a role in lesion progression and stabilization. Despite clear phen…