Daisuke Kiuchi
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View article: Effectiveness of Systemic Corticosteroids in Managing Cancer-Related Neuropathic Pain: A Multicenter Prospective Observational Study
Effectiveness of Systemic Corticosteroids in Managing Cancer-Related Neuropathic Pain: A Multicenter Prospective Observational Study Open
Background: Cancer-related neuropathic pain (CR-NP) is challenging to manage, and the effectiveness of corticosteroids remains underexplored. Objectives: This study investigated the analgesic and functional benefits of corticosteroids in C…
View article: Nurse‐Led Screening‐Triggered Early Specialized Palliative Care Program for Patients With Advanced Lung Cancer: A Multicenter Randomized Controlled Trial
Nurse‐Led Screening‐Triggered Early Specialized Palliative Care Program for Patients With Advanced Lung Cancer: A Multicenter Randomized Controlled Trial Open
Background We aimed to examine the effectiveness of a nurse‐led, screening‐triggered early specialized palliative care intervention program for patients with advanced lung cancer. Methods Patients with advanced lung cancer who underwent in…
View article: Learning about design for dementia: lessons from a Japan–UK network
Learning about design for dementia: lessons from a Japan–UK network Open
A multidisciplinary Japan–UK Network identified cross-cultural and cross-national lessons for research aimed at improving the design of homes for people living with dementia. Previous research has suggested that improved, multidimensionall…
View article: Beliefs and Perceptions About Parenteral Nutrition and Hydration by Advanced Cancer Patients
Beliefs and Perceptions About Parenteral Nutrition and Hydration by Advanced Cancer Patients Open
Background: The beliefs and perceptions of parenteral nutrition and hydration (PNH) by advanced cancer patients have not been elucidated. Objectives: To clarify their beliefs and perceptions and to explore the relationships between their b…
View article: The impact of cachexia on dietary intakes, symptoms, and quality of life in advanced cancer
The impact of cachexia on dietary intakes, symptoms, and quality of life in advanced cancer Open
Background The relationships between cachexia stages and the Functional Assessment of Anorexia/Cachexia Therapy Anorexia Cachexia Subscale (FAACT ACS) 12‐item, 5‐item anorexia symptoms, and 4‐item anorexia concerns have not been investigat…
View article: Beliefs and Perceptions About Parenteral Nutrition and Hydration By Advanced Cancer Patients
Beliefs and Perceptions About Parenteral Nutrition and Hydration By Advanced Cancer Patients Open
Purpose Objectives of this study are to clarify the beliefs and perceptions of parenteral nutrition and hydration (PNH) by patients with advanced cancer and to examine the relationships between their beliefs and perceptions and cachexia st…
View article: Clinical Implications of the Interdisciplinary Psychosocial Approach and Integrative Care for Patients with Advanced Cancer and Family Members in the Nutritional Support and Cancer Cachexia Clinic
Clinical Implications of the Interdisciplinary Psychosocial Approach and Integrative Care for Patients with Advanced Cancer and Family Members in the Nutritional Support and Cancer Cachexia Clinic Open
人は生きるために食べるが，食事は社会的存在である人にとってそれ以上の意味をもつ．進行がん患者は，腫瘍・治療の副作用・がん悪液質のため「食べないといけないが食べられない」「食べるようにしているが痩せてしまう」というような食欲不振・体重減少を主因とする食に関することで苦悩し，生活をともにする家族も患者とは異なる苦悩を有することが近年の研究でわかってきた．これらを踏まえ，われわれは患者と家族の食に関する苦悩のような心理社会的苦痛における緩和ケア・サポーティブケア・栄養ケアを統合し…
View article: Retrospective Survey of Palliative Sedation Therapy at the End-of-life at a Tertiary Cancer Center in Japan
Retrospective Survey of Palliative Sedation Therapy at the End-of-life at a Tertiary Cancer Center in Japan Open
国立がん研究センター中央病院における終末期鎮静の施行状況を後方視的に調査した．2015年4月〜2016年3月に死亡退院した431例中75例（17.4%）に鎮静が施行された．患者背景は男/女48/27例，年齢61（5〜83）歳，原発巣は肺/膵/血液/骨軟部/その他18/11/11/8/27例と若年・希少がんが多く，対象症状は呼吸困難（38例）とせん妄（30例）が多かった．72例でミダゾラムが使用された．死亡時には61例で持続的深い鎮静が実施されており，鎮静開始後の生存期間は2…
View article: A 9-year-old Cancer Patient with Rectal Irritative Symptoms Relieved by Yokukansan: A Case Report
A 9-year-old Cancer Patient with Rectal Irritative Symptoms Relieved by Yokukansan: A Case Report Open
【背景】悪性腫瘍に伴う直腸の刺激症状は多彩で，患者のQuality of Life（QOL）に大きく影響する一方で確立した治療法はない．傍直腸再発腫瘍による掻痒感を伴う直腸刺激症状に対して抑肝散が奏功した小児症例を経験したので報告する．【症例】9歳男児．傍直腸に横紋筋肉腫の再発巣が出現し，徐々に肛門の奥に身の置き所のない不快を感じるようになった．患児は「肛門の奥のかゆみ」と表現し，画像所見と経過から腫瘍による直腸刺激症状と判断した．小児夜泣きに古くから使用されてきた漢方薬で…
View article: Retrospective Study of Team Support for Cancer Patients with Young Children
Retrospective Study of Team Support for Cancer Patients with Young Children Open
子育て世代のがん患者には親役割に関連した特有の気がかりがあるが,患者・家族が求める子ども支援の実態報告は少ない.われわれはその支援の在り方を明らかにするために,当院緩和ケアチームによる子ども支援(2013年4月〜2015年9月)の実際について後方視的に検討した.対象症例患者は131例(男性/女性41/90例),平均年齢43.3歳だった.主な原発巣は消化器,肺・胸膜,乳腺で,進行再発例が約8割だった.子どもの総数は239人,平均年齢は9.6歳.相談は患者のみならず,患者の家族…
View article: The Effect of Continuous Subcutaneous Infusion of Chlorpromazine on Refractory Delirium in Advanced Cancer: Retrospective Study
The Effect of Continuous Subcutaneous Infusion of Chlorpromazine on Refractory Delirium in Advanced Cancer: Retrospective Study Open
研究目的は緩和ケア病棟入院中の難治性せん妄患者に対する,クロルプロマジン持続皮下注射による有効性を観察することである.2013年7月〜2014年5月において2施設の緩和ケア病棟で,せん妄に対し規定量以上の抗精神病薬治療が行われているにもかかわらずDelirium Rating Scale Revised-98(DRS-R-98)≥13で,クロルプロマジン持続皮下注射で治療したすべての患者を対象とした.評価は治療開始前と48時間後と7日後に行い,DRS-R-98<12となる,…
View article: Frequency of Serious Adverse Skin Reactions Caused by Continuous Subcutaneous Administration of Psychotropic Drugs
Frequency of Serious Adverse Skin Reactions Caused by Continuous Subcutaneous Administration of Psychotropic Drugs Open
がん終末期の症状緩和において持続皮下投与は有用であるが,クロルプロマジン・レボメプロマジンの皮膚刺激性が問題になることがある.2010年4月から2013年3月までに,当院緩和ケア病棟において向精神薬(クロルプロマジン・レボメプロマジン・ミダゾラム)を持続皮下投与した全患者について,CTCAE v4.0 Gr.3以上の皮膚有害事象を生じた頻度を調べた.上記3剤のいずれかを持続皮下投与したのは389/603例(64.5%)であった.Gr.3(潰瘍または壊死)以上の皮膚有害事象を…