Daisuke Uchida
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View article: Diabetic Ketoacidosis Triggered by Retropharyngeal Abscess Complicated by Descending Necrotizing Mediastinitis: A Case Report
Diabetic Ketoacidosis Triggered by Retropharyngeal Abscess Complicated by Descending Necrotizing Mediastinitis: A Case Report Open
A 62-year-old woman with poorly controlled type 2 diabetes mellitus presented with a fever and altered consciousness. The patient was diagnosed with diabetic ketoacidosis (DKA) with a positive blood culture for group A Streptococcus. Altho…
View article: Efficacy of diagnosing intraductal papillary mucinous neoplasm with mural nodules by contrast-enhanced endoscopic ultrasound using time–intensity curve analysis with a new support program: A multicenter retrospective study (with video)
Efficacy of diagnosing intraductal papillary mucinous neoplasm with mural nodules by contrast-enhanced endoscopic ultrasound using time–intensity curve analysis with a new support program: A multicenter retrospective study (with video) Open
The contrast ratio calculated using TIC analysis with the support program is potentially useful for differentiating between IPMNs with LGD and those with HGD/IC.
View article: Vendor‐Agnostic Vision Transformer‐Based Artificial Intelligence for Peroral Cholangioscopy: Diagnostic Performance in Biliary Strictures Compared With Convolutional Neural Networks and Endoscopists
Vendor‐Agnostic Vision Transformer‐Based Artificial Intelligence for Peroral Cholangioscopy: Diagnostic Performance in Biliary Strictures Compared With Convolutional Neural Networks and Endoscopists Open
Objectives Accurate diagnosis of biliary strictures remains challenging. This study aimed to develop an artificial intelligence (AI) system for peroral cholangioscopy (POCS) using a Vision Transformer (ViT) architecture and to evaluate its…
View article: Evaluation of the Diagnostic Performance of the Brush/Biopsy Rapid On-Site Evaluation (B-ROSE) in Cases of Bile Duct Stricture: A Prospective, Pilot Study
Evaluation of the Diagnostic Performance of the Brush/Biopsy Rapid On-Site Evaluation (B-ROSE) in Cases of Bile Duct Stricture: A Prospective, Pilot Study Open
Background: Biliary strictures are diagnosed using endoscopic retrograde cholangiopancreatography (ERCP) with brush cytology and biopsy. However, brush cytology shows a sensitivity of 9–56.1% and a diagnostic accuracy of 43–65.4%, while bi…
View article: Endoscopic Bridging Stent Placement Improves Bile Leaks After Hepatic Surgery
Endoscopic Bridging Stent Placement Improves Bile Leaks After Hepatic Surgery Open
Background: Endoscopic treatment is one of the first-line treatments for bile leaks after hepatic surgery. However, detailed reports of endoscopic treatment for bile leaks after hepatic resection (HR) or liver transplantation (LT) are scar…
View article: Morphological transition after medical treatment of emphysematous pyelonephritis over time—case report
Morphological transition after medical treatment of emphysematous pyelonephritis over time—case report Open
Wan's type I and II EPN has been often reported as different pathophysiological entities. Our case shows that these two subtypes may represent stages in the progression of EPN. Medical treatment for type I may permit safe nephrectomy for t…
View article: Comparison of Midazolam and Diazepam for Sedation in Patients Undergoing Double-Balloon Endoscopic Retrograde Cholangiopancreatography: A Propensity Score-Matched Analysis
Comparison of Midazolam and Diazepam for Sedation in Patients Undergoing Double-Balloon Endoscopic Retrograde Cholangiopancreatography: A Propensity Score-Matched Analysis Open
Objective: The sedation method used in double-balloon endoscopic retrograde cholangiopancreatography (DB-ERCP) varies across countries and between healthcare facilities. No previous studies have compared the effects of different benzodiaze…
View article: Endoscopic ultrasonography‐guided removal of a stent that had migrated into the pancreas post‐pancreaticojejunostomy: A case report
Endoscopic ultrasonography‐guided removal of a stent that had migrated into the pancreas post‐pancreaticojejunostomy: A case report Open
A 64‐year‐old woman had undergone subtotal stomach‐preserving pancreaticoduodenectomy for locally advanced pancreatic head cancer. She had an uneventful postoperative course with no recurrence. However, approximately 18 months after surger…
View article: Efficacy and safety of endoscopic ultrasonography‐guided radiofrequency ablation of small pancreatic neuroendocrine neoplasms: A prospective, pilot study
Efficacy and safety of endoscopic ultrasonography‐guided radiofrequency ablation of small pancreatic neuroendocrine neoplasms: A prospective, pilot study Open
Objectives Endoscopic ultrasonography (EUS)‐guided radiofrequency ablation has recently been introduced as one of the management strategies for small pancreatic neuroendocrine neoplasms (PNENs). However, prospective data on its safety and …
View article: Clipping closure length is a crucial factor for delayed bleeding after endoscopic papillectomy: a retrospective multicenter cohort study
Clipping closure length is a crucial factor for delayed bleeding after endoscopic papillectomy: a retrospective multicenter cohort study Open
Background: Bleeding is a serious and frequent adverse event that occurs during and after endoscopic papillectomy (EP). Previous studies have highlighted the effectiveness of preventive clipping closure of the resection site in preventing …
View article: Model Predictive Control of Nonlinear Dynamics Using Online Adaptive Koopman Operators
Model Predictive Control of Nonlinear Dynamics Using Online Adaptive Koopman Operators Open
This paper develops a methodology for adaptive data-driven Model Predictive Control (MPC) using Koopman operators. While MPC is ubiquitous in various fields of engineering, the controller performance can deteriorate if the modeling error b…
View article: Data-driven Koopman Operator-based Prediction and Control Using Model Averaging
Data-driven Koopman Operator-based Prediction and Control Using Model Averaging Open
This work presents a data-driven Koopman operator-based modeling method using a model averaging technique. While the Koopman operator has been used for data-driven modeling and control of nonlinear dynamics, it is challenging to accurately…
View article: Calcific aortic valve disease-associated long noncoding RNA H19 promotes the osteogenic transition of valvular interstitial cells via the JAG1/NOTCH1 axis
Calcific aortic valve disease-associated long noncoding RNA H19 promotes the osteogenic transition of valvular interstitial cells via the JAG1/NOTCH1 axis Open
Background Calcific aortic valve disease (CAVD) is the most prevalent valvular heart disease causing tremendous suffering globally. The osteogenic differentiation of the valvular interstitial cells (VICs) is a key process in the pathogenes…
View article: Effectiveness of data-augmentation on deep learning in evaluating rapid on-site cytopathology at endoscopic ultrasound-guided fine needle aspiration
Effectiveness of data-augmentation on deep learning in evaluating rapid on-site cytopathology at endoscopic ultrasound-guided fine needle aspiration Open
Rapid on-site cytopathology evaluation (ROSE) has been considered an effective method to increase the diagnostic ability of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA); however, ROSE is unavailable in most institutes worl…
View article: Morphological transition after medical treatment of emphysematous pyelonephritis over time
Morphological transition after medical treatment of emphysematous pyelonephritis over time Open
Background Emphysematous pyelonephritis (EPN) is a necrotizing infection characterized by the production of gas in the renal parenchyma, collecting system or perirenal tissue. The treatment strategy, especially for surgical intervention, i…
View article: Clinical significance of gene alterations in oral squamous cell carcinoma
Clinical significance of gene alterations in oral squamous cell carcinoma Open
It is widely known that human malignancies are caused by genomic and epigenomic alterations. In oral squamous cell carcinoma(OSCC), numerous gene alterations have also been reported. However, in clinical practice, these findings are not ut…
View article: Diversity of oral squamous cell carcinoma
Diversity of oral squamous cell carcinoma Open
In this review article, we focus on the diversity of the origin of oral squamous cell carcinoma(OSCC), and discuss cancer stem cells(CSCs) as a key player to explain the malignancy of OSCC. CSCs are a subset of cancer cells that have chara…
View article: MicroRNA-34a-5p: A pivotal therapeutic target in gallbladder cancer
MicroRNA-34a-5p: A pivotal therapeutic target in gallbladder cancer Open
Gallbladder cancer incidence has been increasing globally, and it remains challenging to expect long prognosis with the current systemic chemotherapy. We identified a novel nucleic acid-mediated therapeutic target against gallbladder cance…
View article: Efficacy and factors influencing dosage of roxadustat for erythropoietin-resistant anemia in hemodialysis patients
Efficacy and factors influencing dosage of roxadustat for erythropoietin-resistant anemia in hemodialysis patients Open
【目的】エリスロポエチン抵抗性貧血に対するロキサデュスタット(ROX)の有効性を評価するとともに投与量に影響する因子を探索する.【方法】ダルベポエチンアルファ(DAR)週1回 60 μg以上の42例をROX 100 mg週3回に切り替えた(ROX群).DAR週1回 60 μg未満の40例はそのままDAR投与を継続した(DAR群).18週から24週までの平均Hb値と目標Hb値維持率,24週間のHb値を後方視的に比較した.さらにROXの増量や休薬に影響を及ぼす因子を解析した.【…
View article: Effectiveness of data-augmentation on deep learning in evaluating rapid on-site cytopathology at endoscopic ultrasound-guided fine needle aspiration
Effectiveness of data-augmentation on deep learning in evaluating rapid on-site cytopathology at endoscopic ultrasound-guided fine needle aspiration Open
Rapid on-site cytopathology evaluation (ROSE) has been considered an effective method to increase the diagnostic ability of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA); however, ROSE is unavailable in most institutes worl…
View article: MicroRNA-451a inhibits gemcitabine-refractory biliary tract cancer progression by suppressing the MIF-mediated PI3K/AKT pathway
MicroRNA-451a inhibits gemcitabine-refractory biliary tract cancer progression by suppressing the MIF-mediated PI3K/AKT pathway Open
Gemcitabine is an effective chemotherapeutic agent for biliary tract cancers (BTCs), including gallbladder cancer (GBC) and cholangiocarcinoma (CCA). However, few other effective agents are currently available, particularly for GEM-refract…
View article: Extracting Koopman Operators for Prediction and Control of Non-linear Dynamics Using Two-stage Learning and Oblique Projections
Extracting Koopman Operators for Prediction and Control of Non-linear Dynamics Using Two-stage Learning and Oblique Projections Open
The Koopman operator framework provides a perspective that non-linear dynamics can be described through the lens of linear operators acting on function spaces. As the framework naturally yields linear embedding models, there have been exte…
View article: Usefulness of the artificial intelligence-mediated virtual chromoendoscopy in peroral cholangioscopy
Usefulness of the artificial intelligence-mediated virtual chromoendoscopy in peroral cholangioscopy Open
Chromoendoscopy is mainly used in gastrointestinal endoscopy to enhance the visibility of mucosal abnormalities in the digestive tract, by applying stains to the mucosa during endoscopy. The most commonly used stain in chromoendoscopy is i…
View article: The efficacy of non-anesthesiologist-administered propofol sedation with a target-controlled infusion system during double-balloon endoscopic retrograde cholangiopancreatography
The efficacy of non-anesthesiologist-administered propofol sedation with a target-controlled infusion system during double-balloon endoscopic retrograde cholangiopancreatography Open
Background: The sedation method used during double-balloon endoscopic retrograde cholangiopancreatography (DB-ERCP) differs among countries and/or facilities, and there is no established method. This study aimed to evaluate the efficacy of…
View article: Successful removal of a proximally migrated pancreatic stent using a novel device delivery system
Successful removal of a proximally migrated pancreatic stent using a novel device delivery system Open
The removal of a proximally migrated pancreatic stent is technically challenging [1] [2] [3]. A novel device delivery system (EndoSheather; Piolax) was recently developed, which comprises a slim-tipped guide catheter and pusher tube that f…
View article: Usefulness of red dichromatic imagining for peroral cholangioscopy
Usefulness of red dichromatic imagining for peroral cholangioscopy Open
Peroral cholangioscopy (POCS) was developed as a diagnostic modality to directly observe bile duct lesions that are difficult to visualize by cholangiography. However, one of its main issues is that the images are strongly affected by bile…