Liyu Liu
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View article: Simulation of a back-side illuminated Ge-on-Si single-photon avalanche diode with a light-trapping structure
Simulation of a back-side illuminated Ge-on-Si single-photon avalanche diode with a light-trapping structure Open
Germanium-on-silicon single-photon avalanche diodes (SPADs) leverage the advantages of germanium for absorption and silicon for multiplication, offering excellent CMOS compatibility and significant potential for short-wave infrared (SWIR) …
View article: Effect of overheating on the microstructure of DD5 superalloy
Effect of overheating on the microstructure of DD5 superalloy Open
View article: Research on Optimized Design of FPGA Parallel Processing Structure in New High-speed Signal Acquisition System
Research on Optimized Design of FPGA Parallel Processing Structure in New High-speed Signal Acquisition System Open
In the development of new high-speed signal acquisition system, it is very important to optimize the performance of parallel processing structure of FPGA. At present, the structure is faced with some difficulties, such as unreasonable reso…
View article: Intrinsic pressure as a convenient mechanical framework for dry active matter
Intrinsic pressure as a convenient mechanical framework for dry active matter Open
The identification of local pressure in active matter systems remains a subject of considerable debate. Through theoretical calculations and extensive simulations of various active systems, we demonstrate that intrinsic pressure (defined i…
View article: Predicting Multigene Transcriptional Outcomes Based on Dual-Stream Mamba Neural Network
Predicting Multigene Transcriptional Outcomes Based on Dual-Stream Mamba Neural Network Open
The integration of gene perturbation technology with single-cell RNA sequencing and CRISPR editing has promoted the standardization of perturbation effect studies at the single-cell level. How- ever, the diversity of human cell types and c…
View article: Isolation, identification, and production optimization of natural functional pigments produced by Talaromyces atroroseus LWT-1
Isolation, identification, and production optimization of natural functional pigments produced by Talaromyces atroroseus LWT-1 Open
Natural microbial pigments are gaining attention for their potential in various applications due to their safety and sustainability. In this study, we isolated a high-yielding pigment-producing fungus identified as Talaromyces atroroseus L…
View article: Potential biomarkers of primary resistance to first- and second-generation EGFR-TKIs in non-small-cell lung cancer: a real-world study
Potential biomarkers of primary resistance to first- and second-generation EGFR-TKIs in non-small-cell lung cancer: a real-world study Open
Background: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) significantly improve the prognosis of EGFR-sensitive mutant non-small-cell lung cancer (NSCLC). However, the mechanisms underlying primary resistance to E…
View article: Publisher Correction: Robo-Matter towards reconfigurable multifunctional smart materials
Publisher Correction: Robo-Matter towards reconfigurable multifunctional smart materials Open
View article: Robo-Matter towards reconfigurable multifunctional smart materials
Robo-Matter towards reconfigurable multifunctional smart materials Open
View article: A study on the improvement of ion conductivity of lithium aluminum titanium phosphate-based solid-state electrolyte by the addition of divalent cations
A study on the improvement of ion conductivity of lithium aluminum titanium phosphate-based solid-state electrolyte by the addition of divalent cations Open
Na like super ionic conductors (NASICON)-structure Li 1.3 Al 0.3 Ti 1.7 (PO 4 ) 3 solid electrolyte have attracted attention as high ion conductivity and chemical stability. The M1–M2 voids between the TiO 6 octahedra and PO 4 tetrahedra i…
View article: Effect of secondary orientation on the tensile behavior of single-crystal superalloys with [001] primary orientation at 760 °C
Effect of secondary orientation on the tensile behavior of single-crystal superalloys with [001] primary orientation at 760 °C Open
This study assesses the impact of secondary orientations on the tensile deformation behavior of single-crystal superalloys at mid-temperature of 760 °C. Tensile tests and stress-strain analyses were performed on specimens with primary orie…
View article: Failure of Electron Beam Physical Vapor Deposited Thermal Barrier Coatings System under Cyclic Thermo-Mechanical Loading with a Thermal Gradient
Failure of Electron Beam Physical Vapor Deposited Thermal Barrier Coatings System under Cyclic Thermo-Mechanical Loading with a Thermal Gradient Open
The failure mechanism of a thermal barrier coatings (TBCs) system is investigated using cyclic thermo-mechanical loading with a thermal gradient. Hollow circular cylindrical specimens are employed, consisting of a nickel-based single-cryst…
View article: Microstructure and coloration mechanism of TC11 aerospace titanium alloy ultra-thin thermal oxide films
Microstructure and coloration mechanism of TC11 aerospace titanium alloy ultra-thin thermal oxide films Open
This study explores the microstructure and coloration mechanism of high-saturation structural colors in ultra-thin oxide films formed on TC11 aerospace titanium alloy near permissible engineering temperatures. Utilizing optical microscopy …
View article: Memory of elastic collisions drives high minority spin and oscillatory entropy in underdamped chiral spinners
Memory of elastic collisions drives high minority spin and oscillatory entropy in underdamped chiral spinners Open
Inertial underdamped collisions preserve the memory of physical parameters that existed before the collision, leading to phenomena usually unseen in overdamped systems. Here we probe the less studied inertial chiral matter with spinners on…
View article: SCTC: inference of developmental potential from single-cell transcriptional complexity
SCTC: inference of developmental potential from single-cell transcriptional complexity Open
Inferring the developmental potential of single cells from scRNA-Seq data and reconstructing the pseudo-temporal path of cell development are fundamental but challenging tasks in single-cell analysis. Although single-cell transcriptional d…
View article: AttnPep: A Self-Attention-Based Deep Learning Method for Peptide Identification in Shotgun Proteomics
AttnPep: A Self-Attention-Based Deep Learning Method for Peptide Identification in Shotgun Proteomics Open
In shotgun proteomics, the proteome search engine analyzes\nmass\nspectra obtained by experiments, and then a peptide-spectra match\n(PSM) is reported for each spectrum. However, most of the PSMs identified\nare incorrect, and therefore va…
View article: Lattice Rotation and Deformation Mechanisms under Tensile Loading in a Single-Crystal Superalloy with [001] Misorientation
Lattice Rotation and Deformation Mechanisms under Tensile Loading in a Single-Crystal Superalloy with [001] Misorientation Open
This study investigates how deviation angles close to the [001] orientation affect the tensile properties and deformation behavior of a nickel-based single-crystal superalloy at room temperature. The research focuses on samples with deviat…
View article: Morphological entropy encodes cellular migration strategies on multiple length scales
Morphological entropy encodes cellular migration strategies on multiple length scales Open
View article: An entropy-based approach for assessing the directional persistence of cell migration
An entropy-based approach for assessing the directional persistence of cell migration Open
View article: Morphological Entropy Encodes Cellular Migration Strategies on Multiple Length Scales
Morphological Entropy Encodes Cellular Migration Strategies on Multiple Length Scales Open
Cell migration is crucial for numerous physiological and pathological processes. A cell adapts its morphology, including the overall and nuclear morphology, in response to various cues in complex microenvironments, such as topotaxis and ch…
View article: Emergence of Broken Symmetry Via Odd Viscosity in Underdamped Spinner Swarms
Emergence of Broken Symmetry Via Odd Viscosity in Underdamped Spinner Swarms Open
Broken symmetry is an emergent phenomena. We show here the unexpected broken symmetry emergence of high spin state minority spinners in an active swarm of mixed spin handedness internally driven spinners. This occurs because depending on t…
View article: Morphological entropy encodes cellular migration strategies on multiple length scales
Morphological entropy encodes cellular migration strategies on multiple length scales Open
Cell migration is crucial to many physiological and pathological processes. During migration, a cell adapts its morphology, including the overall morphology and nucleus morphology, in response to various cues in complex microenvironments, …
View article: Bio-inspired environmental adaptability of swarm active matter
Bio-inspired environmental adaptability of swarm active matter Open
How biologically active matters survive adaptively in complex and changeable environments is a common concern of scientists. Genetics, evolution and natural selection are vital factors in the process of biological evolution and are also th…
View article: Orderly hysteresis in field-driven robot swarm active matter
Orderly hysteresis in field-driven robot swarm active matter Open
Boundary effect and time-reversal symmetry are hot topics in active matter. We present a biology-inspired robot-environment-interaction active matter system with the field-drive motion and the rules of resource search, resource consumption…
View article: Inertial Spinner Swarm Experiments: Spin Pumping, Entropy Oscillations and Spin Frustration
Inertial Spinner Swarm Experiments: Spin Pumping, Entropy Oscillations and Spin Frustration Open
We present here an inertial active spinning swarm consisting of mixtures of opposite handedness torque driven spinners floating on an air bed with low damping. Depending on the relative spin sign, spinners can act as their own anti-particl…
View article: Prospects of Sulfide-Based Solid-State Electrolytes Modified by Organic Thin Films
Prospects of Sulfide-Based Solid-State Electrolytes Modified by Organic Thin Films Open
Lithium-ion batteries are key to tackling today’s energy crisis. In recent years, compared with the research on other components of lithium-ion batteries, the research on solid-state electrolytes is particularly hot. Among various solid-st…
View article: 3D collagen microchamber arrays for combined chemotherapy effect evaluation on cancer cell numbers and migration
3D collagen microchamber arrays for combined chemotherapy effect evaluation on cancer cell numbers and migration Open
Breast cancer metastasis involves complex mechanisms, particularly when patients are undergoing chemotherapy. In tissues, tumor cells encounter cell–cell interactions, cell–microenvironment interactions, complex nutrient, and drug gradient…
View article: Robots as models of evolving systems
Robots as models of evolving systems Open
Significance We present a fully realized adaptive resource landscape with diploid three-gene robots presenting interacting roles of population dynamics, mutations, breeding, death, and birth. Although modeling and theory serves as a guide …
View article: CITEMO <sup>XMBD</sup> : A flexible single-cell multimodal omics analysis framework to reveal the heterogeneity of immune cells
CITEMO <sup>XMBD</sup> : A flexible single-cell multimodal omics analysis framework to reveal the heterogeneity of immune cells Open
Simultaneous measurement of multiple modalities in single-cell analysis, represented by CITE-seq, is a promising approach to link transcriptional changes to cellular phenotype and function, requiring new computational methods to define cel…
View article: Biophysical model for high-throughput tumor and epithelial cell co-culture in complex biochemical microenvironments
Biophysical model for high-throughput tumor and epithelial cell co-culture in complex biochemical microenvironments Open
The in vivo tumor microenvironment is a complex niche that includes heterogeneous physical structures, unique biochemical gradients and multiple cell interactions. Its high-fidelity in vitro reconstruction is of fundamental importance to i…