Dali Meng
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View article: Barrigenol‐Like Triterpenoid Saponins From the Husks of <i>Xanthoceras sorbifolia</i> Bunge and Their Cytotoxicity
Barrigenol‐Like Triterpenoid Saponins From the Husks of <i>Xanthoceras sorbifolia</i> Bunge and Their Cytotoxicity Open
The phytochemical study on Xanthoceras sorbifolium Bunge husks, a folk medicinal plant in China, led to the isolation of ten saponins including four new compounds from this plant. Their structures were elucidated based on physical and chem…
View article: Statins Diversity Revealed by the Deep-Sea-Derived Fungus Penicillium viridicatum
Statins Diversity Revealed by the Deep-Sea-Derived Fungus Penicillium viridicatum Open
Seven new (1–7) and six known (8–13) statin derivatives were obtained from the deep-sea-derived fungus Penicillium viridicatum MCCC 3A00265. The structures assigned to the new compounds were based on a comprehensive analysis of the spectro…
View article: Study on the Chemical Constituents of Different Parts of <i>Xanthoceras sorbifolia</i> Bunge Based on Plant Metabolomics
Study on the Chemical Constituents of Different Parts of <i>Xanthoceras sorbifolia</i> Bunge Based on Plant Metabolomics Open
Xanthoceras sorbifolia is valued in food, landscape, and medicine, with its husk containing triterpenoid saponin known for anti‐Alzheimer's effects. This study, using ultra‐high‐performance liquid chromatography coupled with high‐resolutio…
View article: Insights into Euphorbia diversity: Probing the contrasts between Euphorbia fischeriana Steud and Euphorbia ebracteolata Hayata
Insights into Euphorbia diversity: Probing the contrasts between Euphorbia fischeriana Steud and Euphorbia ebracteolata Hayata Open
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View article: A high-efficiency integrated strategy for the targeted discovery of novel barrigenol-type triterpenoid saponins from the shell of Xanthoceras sorbifolium Bunge by offline two-dimensional chromatography-Orbitrap mass spectrometry, neutral loss data acquisition, and predicted natural product screening
A high-efficiency integrated strategy for the targeted discovery of novel barrigenol-type triterpenoid saponins from the shell of Xanthoceras sorbifolium Bunge by offline two-dimensional chromatography-Orbitrap mass spectrometry, neutral loss data acquisition, and predicted natural product screening Open
Natural products are considered as potential sources of leading compounds and play an important role in drug discovery. The liquid chromatography-mass spectrometry (LC-MS) technique is a powerful tool for compound-guided isolation from nat…
View article: Front Cover: Chemical Constituents of the Deep‐sea Gammarid Shrimp‐Derived Fungus <i>Penicillium citrinum</i> XIA‐16 (Chem. Biodiversity 11/2023)
Front Cover: Chemical Constituents of the Deep‐sea Gammarid Shrimp‐Derived Fungus <i>Penicillium citrinum</i> XIA‐16 (Chem. Biodiversity 11/2023) Open
Graphical Abstract Front Cover. From the deep-sea gammarid shrimp-derived Penicillium citrinum XIA-16, one new and 25 known compounds were obtained. Penicitrinol B significantly inhibited RSL3-induced ferroptosis by reducing lipid peroxida…
View article: Triterpenoids from <i>Meehania fargesii</i> with Cytotoxic Activity<sup>1</sup>
Triterpenoids from <i>Meehania fargesii</i> with Cytotoxic Activity<sup>1</sup> Open
In the investigation of Meehania fargesii , eighteen triterpenoids were isolated and identified, including a previously unknown compound with an 13,27‐cycloursane skeleton, using techniques like 1D and 2D NMR, and HR‐MS. Furthermore, the c…
View article: CCDC 2170388: Experimental Crystal Structure Determination
CCDC 2170388: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2170389: Experimental Crystal Structure Determination
CCDC 2170389: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Guaianolide Sesquiterpenes With Significant Antiproliferative Activities From the Leaves of Artemisia argyi
Guaianolide Sesquiterpenes With Significant Antiproliferative Activities From the Leaves of Artemisia argyi Open
Four new guaiane-type sesquiterpenes, argyin H–K (1–4), and two known analogues (5 and 6) were isolated from the leaves of Artemisia argyi Lévl et Vant. The new compounds were characterized by the basic analysis of the spectroscopic data o…
View article: MgAl monolayer hydrotalcite increases the hypoglycemic effect of berberine by enhancing its oral bioavailability
MgAl monolayer hydrotalcite increases the hypoglycemic effect of berberine by enhancing its oral bioavailability Open
Berberine (BBR) is a potential novel agent to treat diabetes, but its oral bioavailability is restricted by the poor solubility, which greatly limits its clinical application. Here, a new drug delivery system of BBR-MgAl monolayer hydrotal…
View article: Predictive models for Talaromyces marneffei infection in HIV-infected patients using routinely collected data
Predictive models for Talaromyces marneffei infection in HIV-infected patients using routinely collected data Open
ObjectivesLate diagnosis of Talaromyces marneffei ( T. marneffei ) in patients with HIV/AIDS infection is strongly associated with greater mortality. To date, effective predictive model for T. marneffe i infection in clinical practice have…
View article: Systems Pharmacological Approach to Investigate the Mechanism of Ohwia caudata for Application to Alzheimer’s Disease
Systems Pharmacological Approach to Investigate the Mechanism of Ohwia caudata for Application to Alzheimer’s Disease Open
Ohwia caudata (OC)—a traditional Chinese medicine (TCM)—has been reported to have large numbers of flavonoids, alkaloids, and triterpenoids. The previous studies on OC for treating Alzheimer’s disease (AD) only focused on single targets an…
View article: Characterization and abolishment of the cyclopiazonic acids produced by <i>Aspergillus oryzae</i> HMP-F28
Characterization and abolishment of the cyclopiazonic acids produced by <i>Aspergillus oryzae</i> HMP-F28 Open
Extracellular alkalinization and H2O2 production are important early events during induced resistance establishment in plants. In a screen for metabolites as plant resistance activators from 98 fungal isolates associated with marine sponge…
View article: UPLC-QTOF/MSE and Bioassay Are Available Approaches for Identifying Quality Fluctuation of Xueshuantong Lyophilized Powder in Clinic
UPLC-QTOF/MSE and Bioassay Are Available Approaches for Identifying Quality Fluctuation of Xueshuantong Lyophilized Powder in Clinic Open
Xueshuantong Lyophilized Powder (XST), consisting of a series of saponins extracted from Panax notoginseng, is widely applied to treat acute cerebral infarction, stroke, and coronary heart disease in China. However, most adverse drug react…
View article: Potential anti-inflammation nor-oleanane triterpenoids from the fruits of <i>Stauntonia brachyanthera</i>
Potential anti-inflammation nor-oleanane triterpenoids from the fruits of <i>Stauntonia brachyanthera</i> Open
The studies on Stauntonia brachyanthera led to the isolations of 7 normal and nor-oleanane triterpenoids, including 2 new ones. Compounds 1 and 3 showed moderate inhibitory activity on lipopolysaccharide (LPS)-induced nitric oxide producti…
View article: A green and facile preparation approach, licochalcone A capped on hollow gold nanoparticles, for improving the solubility and dissolution of anticancer natural product
A green and facile preparation approach, licochalcone A capped on hollow gold nanoparticles, for improving the solubility and dissolution of anticancer natural product Open
This study described a valuable drug delivery system for poorly water-soluble anticancer naturalproduct, licochalcone A, isolated from Glycyrrhiza inflata, loaded on hollow gold nanoparticles by green method to improve solubility and disso…
View article: Brachyantheraoside A<sub>8</sub>, a new natural nor-oleanane triterpenoid as a kidney-type glutaminase inhibitor from<i>Stauntonia brachyanthera</i>
Brachyantheraoside A<sub>8</sub>, a new natural nor-oleanane triterpenoid as a kidney-type glutaminase inhibitor from<i>Stauntonia brachyanthera</i> Open
With the aim of finding a better kidney-type glutaminase (KGA) inhibitor with potential anti-cancer properties, 18 nor-oleanane triterpenoids fromStauntonia brachyanthera, including 2 new ones, were screened against KGA.