Damien Rioult
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View article: Distinct oxidative and photosynthetic responses to betulin and betulone in the freshwater microalgae Chlamydomonas reinhardtii
Distinct oxidative and photosynthetic responses to betulin and betulone in the freshwater microalgae Chlamydomonas reinhardtii Open
Natural products are increasingly used in therapeutic, cosmetic, and eco-friendly applications, yet their impacts on aquatic ecosystems remain understudied. We investigated the effects of two birch-derived triterpenes, betulin and betulone…
View article: Unveiling the hidden threat: Molecular, cellular and behavioral effects of dietborne inorganic mercury and methylmercury in Dreissena polymorpha
Unveiling the hidden threat: Molecular, cellular and behavioral effects of dietborne inorganic mercury and methylmercury in Dreissena polymorpha Open
Methylmercury (MeHg) bioaccumulation in food webs has been recognized as a significant health risk for over 50 years, yet most studies focus on high concentrations of waterborne inorganic mercury (IHg). This study investigates the effects …
View article: LRP-1-dependent control of calpain expression and activity: A new mechanism regulating thyroid carcinoma cell adhesion
LRP-1-dependent control of calpain expression and activity: A new mechanism regulating thyroid carcinoma cell adhesion Open
The low-density lipoprotein receptor-related protein 1 (LRP1) is a multifunctional endocytic receptor mediating the clearance of various molecules from the extracellular matrix. LRP1 also regulates cell surface expression of matrix recepto…
View article: Xylanase production by Thermobacillus xylanilyticus is impaired by population diversification but can be mitigated based on the management of cheating behavior
Xylanase production by Thermobacillus xylanilyticus is impaired by population diversification but can be mitigated based on the management of cheating behavior Open
Background The microbial production of hemicellulasic cocktails is still a challenge for the biorefineries sector and agro-waste valorization. In this work, the production of hemicellulolytic enzymes by Thermobacillus xylanilyticus has bee…
View article: Xylanase Production By Thermobacillus Xylanilyticus is Impaired By Population Diversification But Can Be Mitigated Based On the Management of Cheating Behavior
Xylanase Production By Thermobacillus Xylanilyticus is Impaired By Population Diversification But Can Be Mitigated Based On the Management of Cheating Behavior Open
Background: The microbial production of hemicellulasic cocktails is still a challenge for the sector of biorefineries and agro-waste valorization. In this work, the production of hemicellulolytic enzymes by Thermobacillus xylanilyticus has…
View article: Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity
Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity Open
TAX2 peptide is a cyclic peptide that acts as an orthosteric antagonist for thrombospondin-1 (TSP-1) interaction with CD47. TAX2 was first described for its anti-angiogenic activities and showed anti-cancer efficacy in numerous preclinical…
View article: LRP-1 Promotes Colon Cancer Cell Proliferation in 3D Collagen Matrices by Mediating DDR1 Endocytosis
LRP-1 Promotes Colon Cancer Cell Proliferation in 3D Collagen Matrices by Mediating DDR1 Endocytosis Open
Low density lipoprotein receptor related protein-1 (LRP-1) is a large ubiquitous endocytic receptor mediating the clearance of various molecules from the extracellular matrix. Several studies have shown that LRP-1 plays crucial roles durin…
View article: Brucella melitensis Rev.1 vaccination generates a higher shedding risk of the vaccine strain in Alpine ibex (Capra ibex) compared to the domestic goat (Capra hircus)
Brucella melitensis Rev.1 vaccination generates a higher shedding risk of the vaccine strain in Alpine ibex (Capra ibex) compared to the domestic goat (Capra hircus) Open
Epidemiological investigations implemented in wild and domestic ruminants evidenced a reservoir for Brucella in Capra ibex in the French Alps. Vaccination was considered as a possible way to control Brucella infection in this wildlife popu…
View article: Genotoxic and Cytotoxic Effects on the Immune Cells of the Freshwater Bivalve Dreissena polymorpha Exposed to the Environmental Neurotoxin BMAA
Genotoxic and Cytotoxic Effects on the Immune Cells of the Freshwater Bivalve Dreissena polymorpha Exposed to the Environmental Neurotoxin BMAA Open
The environmental neurotoxin β-N-Methylamino-l-alanine (BMAA) has been pointed out to be involved in human neurodegenerative diseases. This molecule is known to be bioaccumulated by bivalves. However, little data about its toxic effects on…
View article: Mussel as a Tool to Define Continental Watershed Quality
Mussel as a Tool to Define Continental Watershed Quality Open
Bivalves appear as relevant sentinel species in aquatic ecotoxicology and water quality assessment. This is particularly true in marine ecosystems. In fact, several biomonitoring frameworks in the world used mollusks since several decades …
View article: Evidence for P-Glycoprotein Involvement in Cell Volume Regulation Using Coulter Sizing in Flow Cytometry
Evidence for P-Glycoprotein Involvement in Cell Volume Regulation Using Coulter Sizing in Flow Cytometry Open
The regulation of cell volume is an essential function that is coupled to a variety of physiological processes such as receptor recycling, excitability and contraction, cell proliferation, migration, and programmed cell death. Under stress…