Dan Farahmand
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View article: Postoperative changes in ventricular cerebrospinal fluid biomarkers with correlation to clinical outcome in idiopathic normal pressure hydrocephalus
Postoperative changes in ventricular cerebrospinal fluid biomarkers with correlation to clinical outcome in idiopathic normal pressure hydrocephalus Open
Background Ventricular cerebrospinal fluid (CSF) was analysed peri- and postoperatively to elucidate the pathophysiology of Idiopathic normal pressure hydrocephalus (iNPH). Objective To capture the dynamics of biomarkers and their relation…
View article: Observations from the first 100 cases of intraoperative MRI – experiences, trends and short-term outcomes
Observations from the first 100 cases of intraoperative MRI – experiences, trends and short-term outcomes Open
Background We sought to analyze, in well-defined clinical setting, the first 100 patients treated at the intraoperative MRI (iMRI) hybrid surgical theatre at our facility in a population-based setting to evaluate which pathologies are best…
View article: Decrease of excessive daytime sleepiness after shunt treatment for normal pressure hydrocephalus
Decrease of excessive daytime sleepiness after shunt treatment for normal pressure hydrocephalus Open
Summary Sleepiness and apathy are often reported in patients with normal pressure hydrocephalus. However, research on outcomes after shunt surgery has mainly focused on the classical triad symptoms, that is, gait, cognition, and bladder dy…
View article: Headache in patients with non-functioning pituitary adenoma before and after transsphenoidal surgery – a prospective study
Headache in patients with non-functioning pituitary adenoma before and after transsphenoidal surgery – a prospective study Open
Purpose To study the long-term effect of transsphenoidal surgery (TSS) on headache in patients with non-functioning pituitary adenoma (NFPA) and identify factors predicting headache relief following TSS. Methods We evaluated headache in 10…
View article: Volumetric effect of shunt adjustments in normal pressure hydrocephalus: a randomized, double-blind trial
Volumetric effect of shunt adjustments in normal pressure hydrocephalus: a randomized, double-blind trial Open
OBJECTIVE MRI volumetry could be used as an alternative to invasive tests of shunt function. In this study, the authors aimed to assess the difference in ventricular volume (VV) before and after surgery and at different performance levels …
View article: Evaluation of a Fully Automated Method for Ventricular Volume Segmentation Before and After Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus
Evaluation of a Fully Automated Method for Ventricular Volume Segmentation Before and After Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus Open
A fully automated volumetric method permits reliable evaluation of preoperative ventriculomegaly and postoperative ventricular volume change in idiopathic normal pressure hydrocephalus.
View article: P07.14.A OBSERVATIONS FROM THE FIRST 100 CASES OF INTRAOPERATIVE MRI - EXPERIENCES, TRENDS AND SHORT-TERM OUTCOMES IN PEDIATRIC VERSUS ADULT NEUROSURGICAL POPULATION
P07.14.A OBSERVATIONS FROM THE FIRST 100 CASES OF INTRAOPERATIVE MRI - EXPERIENCES, TRENDS AND SHORT-TERM OUTCOMES IN PEDIATRIC VERSUS ADULT NEUROSURGICAL POPULATION Open
BACKGROUND The intraoperative MRI (iMRI) at Sahlgrenska University Hospital installed in 2017 was the first introduced in Sweden. Herein, we present a single center study with our observations from the first 100 patients undergoing neurosu…
View article: Ventricular volume in relation to lumbar CSF levels of amyloid-β 1–42, tau and phosphorylated tau in iNPH, is there a dilution effect?
Ventricular volume in relation to lumbar CSF levels of amyloid-β 1–42, tau and phosphorylated tau in iNPH, is there a dilution effect? Open
Background Levels of the biomarkers amyloid-β 1–42 (Aβ42), tau and phosphorylated tau (p-tau) are decreased in the cerebrospinal fluid (CSF) of patients with idiopathic normal pressure hydrocephalus (iNPH). The mechanism behind this is unk…
View article: Headache Before and After Endoscopic Transsphenoidal Pituitary Tumor Surgery: A Prospective Study
Headache Before and After Endoscopic Transsphenoidal Pituitary Tumor Surgery: A Prospective Study Open
Objective Headache is a common symptom among patients with pituitary tumors, as it is in the general population. The aim of the study was to investigate headache as a symptom in patients with pituitary tumors before and 6 months after endo…
View article: Endoscopic versus open microsurgery for colloid cysts of the third ventricle
Endoscopic versus open microsurgery for colloid cysts of the third ventricle Open
ES showed similar neurologic outcomes and complications compared to OS for colloid cysts of the third ventricle. ES showed significantly shorter operative times and hospital stays compared to OS.
View article: Circulating brain injury biomarkers increase after endoscopic surgery for pituitary tumors
Circulating brain injury biomarkers increase after endoscopic surgery for pituitary tumors Open
Pituitary tumors and subsequent treatment with endoscopic transsphenoidal surgery (ETSS) may cause injury to suprasellar structures, causing long-term fatigue and neurocognitive impairment. A method to quantify brain injury after ETSS is n…
View article: Sinonasal Symptoms and Self-Reported Health before and after Endoscopic Pituitary Surgery—A Prospective Study
Sinonasal Symptoms and Self-Reported Health before and after Endoscopic Pituitary Surgery—A Prospective Study Open
Objectives Despite the limited invasiveness of endoscopic transsphenoidal surgery (ETSS), some degree of nasal structure destruction is unavoidable. Our objective was to evaluate sinonasal morbidity and self-reported health before and 6 mo…
View article: Virtual magnetic resonance elastography has the feasibility to evaluate preoperative pituitary adenoma consistency
Virtual magnetic resonance elastography has the feasibility to evaluate preoperative pituitary adenoma consistency Open
Purpose To evaluate the use of preoperative virtual Magnetic Resonance Elastography (vMRE) for patients undergoing transsphenoidal resection of pituitary adenomas (PA). Methods Ten patients (60.2 ± 19.6 years; 8 males) were prospectively e…
View article: Ventricular Volume Is More Strongly Associated with Clinical Improvement Than the Evans Index after Shunting in Idiopathic Normal Pressure Hydrocephalus
Ventricular Volume Is More Strongly Associated with Clinical Improvement Than the Evans Index after Shunting in Idiopathic Normal Pressure Hydrocephalus Open
Clinical improvement after shunt surgery in idiopathic normal pressure hydrocephalus is associated with a reduction of ventricular size. Ventricular volume is a more sensitive estimate than the Evans index and, therefore, constitutes a mor…
View article: The risk of ventricular catheter misplacement and intracerebral hemorrhage in shunt surgery for hydrocephalus
The risk of ventricular catheter misplacement and intracerebral hemorrhage in shunt surgery for hydrocephalus Open
Ventricular shunt insertion is a commonly performed neurosurgical procedure but few studies evaluate the rates of ventricular catheter (VC) misplacement and postoperative intracerebral hemorrhage (ICH) after shunt surgery. In this study, w…
View article: Three-Dimensional Volumetric Segmentation of Pituitary Tumors: Assessment of Inter-rater Agreement and Comparison with Conventional Geometric Equations
Three-Dimensional Volumetric Segmentation of Pituitary Tumors: Assessment of Inter-rater Agreement and Comparison with Conventional Geometric Equations Open
Background The assessment of pituitary tumor (PT) volume is important in the treatment and follow-up of patients with PT. Previously, PT volume estimation has been performed by conventional geometric equations (CGE) such as abc/2 (simplifi…