Dan M. Meyer
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View article: Clinical Course and Outcomes of Cardiogenic Shock in COVID-19 : Insights from COVID-19 Critical Care Consortium
Clinical Course and Outcomes of Cardiogenic Shock in COVID-19 : Insights from COVID-19 Critical Care Consortium Open
Aim: Cardiogenic shock (CS) is a life-threatening condition observed in patients with severe heart diseases. Although COVID-19 is known to cause cardiac complications, the epidemiology and outcomes of CS in COVID-19 patients have not been …
View article: Increasing the acceptance of thoraco-abdominal normothermic regional perfusion in DCD heart donation: A case for collaborative donor research
Increasing the acceptance of thoraco-abdominal normothermic regional perfusion in DCD heart donation: A case for collaborative donor research Open
Donation after circulatory determination of death transplantation offers an effective and safe method of increasing the number of heart transplants performed. Donation after circulatory determination of death heart is ischemic at the time …
View article: Chilling Choices: Heart Transplant Outcomes Using SherpaPak With Long Ischemic Time Versus Traditional Ice Storage With Short Ischemic Time
Chilling Choices: Heart Transplant Outcomes Using SherpaPak With Long Ischemic Time Versus Traditional Ice Storage With Short Ischemic Time Open
We performed a retrospective review comparing outcomes between traditional ice storage (ICE) with short ischemic times (4 hours) using data from the GUARDIAN registry, a retrospective observational trial. To minimize baseline differences, …
View article: Impact of controlled hypothermic preservation on outcomes following heart transplantation
Impact of controlled hypothermic preservation on outcomes following heart transplantation Open
Severe PGD is the deadliest complication of heart transplantation and is associated with a 7.8-fold increase in probability of 1-year mortality. Controlled hypothermic preservation significantly attenuates the risk of severe PGD and is a s…
View article: Outcomes in Heart Transplant Recipients by Bridge to Transplant Strategy When Using the SherpaPak Cardiac Transport System
Outcomes in Heart Transplant Recipients by Bridge to Transplant Strategy When Using the SherpaPak Cardiac Transport System Open
The last several years have seen a rise in use of mechanical circulatory support (MCS) to bridge heart transplant recipients. A controlled hypothermic organ preservation system, the SherpaPak Cardiac Transport System (SCTS), was introduced…
View article: Heightening awareness in the detection and management of arrhythmic mitral valve prolapse
Heightening awareness in the detection and management of arrhythmic mitral valve prolapse Open
Mitral valve prolapse (MVP) is present in 2-3% of the general population. A small percentage of these patients develop sudden cardiac death. Although there have been several clinical, EKG, and imaging findings associated with sudden death …
View article: Repair of Dissecting Aortic Aneurysm in Post-LVAD Patient
Repair of Dissecting Aortic Aneurysm in Post-LVAD Patient Open
Left ventricular assist devices (LVAD) are frequently used in the management of end-stage heart failure, especially given the limited availability of donor hearts. The latest HeartMate 3 LVAD delivers non-physiological continuous flow (CF)…
View article: Recipient Outcomes With Extended Criteria Donors Using Advanced Heart Preservation: An Analysis of the GUARDIAN-Heart Registry
Recipient Outcomes With Extended Criteria Donors Using Advanced Heart Preservation: An Analysis of the GUARDIAN-Heart Registry Open
This subgroup analysis demonstrates that SherpaPak can be safely used to utilize extended criteria donors with low severe PGD rates.
View article: Early elevated donor‐derived cell‐free DNA levels in heart transplant recipients following precision‐controlled cardiac transport system or ice‐cooled organ transport
Early elevated donor‐derived cell‐free DNA levels in heart transplant recipients following precision‐controlled cardiac transport system or ice‐cooled organ transport Open
Background Recent innovations in temperature‐controlled cardiac transportation allow for static hypothermic preservation of transplant organs during transportation. We assessed differences in donor‐derived cell‐free DNA (dd‐cfDNA) using th…
View article: Malignancy-Associated Non-Bacterial Thrombotic Endocarditis Causing Aortic Regurgitation and Leading to Aortic Valve Replacement
Malignancy-Associated Non-Bacterial Thrombotic Endocarditis Causing Aortic Regurgitation and Leading to Aortic Valve Replacement Open
Described herein is a 48-year-old woman with metastatic ovarian cancer who developed aortic regurgitation considered clinically to be the result of infective endocarditis but operative resection of the three aortic valve cusps disclosed th…
View article: Effect of Progressive Left Ventricular Dilatation on Degree of Mitral Regurgitation Secondary to Mitral Valve Prolapse
Effect of Progressive Left Ventricular Dilatation on Degree of Mitral Regurgitation Secondary to Mitral Valve Prolapse Open
Described herein is a 71-year-old man who at age 61 was found by echocardiogram to have severe mitral regurgitation (MR) from mitral valve prolapse. During the subsequent 9 years the MR progressively lessened as his left ventricular cavity…
View article: Correction : Epidemiology and outcomes of early-onset AKI in COVID-19-related ARDS in comparison with non-COVID-19-related ARDS: insights from two prospective global cohort studies
Correction : Epidemiology and outcomes of early-onset AKI in COVID-19-related ARDS in comparison with non-COVID-19-related ARDS: insights from two prospective global cohort studies Open
Following publication of the original article [1], the authors identified that the collaborating authors part of the collaborating author group CCCC Consortium was missing. The collaborating author group is available and included as Additi…
View article: A Paradigm Shift in Heart Preservation: Improved Post-transplant Outcomes in Recipients of Donor Hearts Preserved With the SherpaPak System
A Paradigm Shift in Heart Preservation: Improved Post-transplant Outcomes in Recipients of Donor Hearts Preserved With the SherpaPak System Open
Traditional ice storage has been the historic standard for preserving donor’s hearts. However, this approach provides variability in cooling, increasing risks of freezing injury. To date, no preservation technology has been reported to imp…
View article: HeartMate 3 Explantation Using Felt Plug for Ventriculotomy Occlusion
HeartMate 3 Explantation Using Felt Plug for Ventriculotomy Occlusion Open
Left ventricular assist devices (LVAD) can be utilized for heart failure patients as a bridge to transplant, bridge to destination, or bridge to recovery. Given the lack of a universally accepted consensus for assessing myocardial recovery…
View article: Multicenter Registry Using Propensity Score Analysis to Compare a Novel Transport/Preservation System to Traditional Means on Postoperative Hospital Outcomes and Costs for Heart Transplant Patients
Multicenter Registry Using Propensity Score Analysis to Compare a Novel Transport/Preservation System to Traditional Means on Postoperative Hospital Outcomes and Costs for Heart Transplant Patients Open
The standard method for cardiac allograft preservation for the past 50 years has been static storage using crushed ice. A heart transplant transportation system designed to improve preservation quality with temperature monitoring, the Para…
View article: Extracorporeal membrane oxygenation for respiratory failure in phases of COVID‐19 variants
Extracorporeal membrane oxygenation for respiratory failure in phases of COVID‐19 variants Open
There was no significant difference in survival or time on ECMO support in patients during the peak prevalence of the three variants.
View article: Laparoscopic repair of large diaphragmatic hernia after left ventricular assist device implantation followed by orthotopic heart transplantation
Laparoscopic repair of large diaphragmatic hernia after left ventricular assist device implantation followed by orthotopic heart transplantation Open
In patients with advanced heart failure and deteriorating clinical status, a left ventricular assist device (LVAD) can be used as a bridge to transplantation or as an alternative to transplantation. An uncommon complication of orthotopic h…
View article: Extracorporeal membrane oxygenation for COVID-19: lessons learned
Extracorporeal membrane oxygenation for COVID-19: lessons learned Open
Background: The use of extracorporeal membrane oxygenation (ECMO) for the management of severe acute respiratory distress syndrome (ARDS) secondary to the 2019 coronavirus (COVID-19) has been described. However, the management of this comp…
View article: Development of a culturally and linguistically sensitive virtual reality educational platform to improve vaccine acceptance within a refugee population: the SHIFA community engagement-public health innovation programme
Development of a culturally and linguistically sensitive virtual reality educational platform to improve vaccine acceptance within a refugee population: the SHIFA community engagement-public health innovation programme Open
Objectives To combat misinformation, engender trust and increase health literacy, we developed a culturally and linguistically appropriate virtual reality (VR) vaccination education platform using community-engaged approaches within a Soma…
View article: O7 Toll-like receptor 3 mediates osteoblastic phenotype switch in calcific aortic valve disease
O7 Toll-like receptor 3 mediates osteoblastic phenotype switch in calcific aortic valve disease Open
Introduction Calcific aortic valve disease (CAVD) is caused by an osteoblastic phenotype switch of valvular interstitial cells (VICs), the predominant cell type in heart valves. However, the trigger for the phenotype switch remains unknown…
View article: Long-term outcomes of patients with primary graft dysfunction after cardiac transplantation
Long-term outcomes of patients with primary graft dysfunction after cardiac transplantation Open
OBJECTIVES The International Society of Heart and Lung Transplantation (ISHLT) criteria for primary graft dysfunction (PGD) after cardiac transplantation have been shown to stratify patient outcomes up to 1 year after transplantation, but …