Dan Lipsker
YOU?
Author Swipe
View article: Peripheral positioning of lysosomes supports melanoma aggressiveness
Peripheral positioning of lysosomes supports melanoma aggressiveness Open
Emerging evidence suggests that the function and position of organelles are pivotal for tumor cell dissemination. Among them, lysosomes stand out as they integrate metabolic sensing with gene regulation and secretion of proteases. Yet, how…
View article: Schnitzler Syndrome: Insights into Its Pathogenesis, Clinical Manifestations, and Current Management
Schnitzler Syndrome: Insights into Its Pathogenesis, Clinical Manifestations, and Current Management Open
Schnitzler syndrome is a rare disorder characterized by a chronic urticarial rash associated with immunoglobulin M (IgM) monoclonal gammopathy. Schnitzler syndrome shares strong clinicopathologic similarities with monogenic IL-1-mediated a…
View article: Peripheral positioning of lysosomes supports melanoma aggressiveness
Peripheral positioning of lysosomes supports melanoma aggressiveness Open
Emerging evidences suggest that function and position of organelles are pivotal for tumor cell dissemination. Among them, lysosomes stand out as they integrate metabolic sensing with gene regulation and secretion of proteases. Yet, how the…
View article: A Rare Cause of Refractory Anaemia hidden between Folds
A Rare Cause of Refractory Anaemia hidden between Folds Open
A 33-year-old-man consulted for brittle nails. He had a previous history of bone and joint pain, recurrent gastrointestinal bleeding secondary to multiple mucosal ulcerations of unknown cause, and microcytic hypochromic anaemia since infan…
View article: Refining Incidence and Characteristics of Inflammatory Myopathies: A <scp>Quadruple‐Source Capture–Recapture</scp> Survey Using the 2017 <scp>European League Against Rheumatism</scp>/American College of Rheumatology Classification Criteria
Refining Incidence and Characteristics of Inflammatory Myopathies: A <span>Quadruple‐Source Capture–Recapture</span> Survey Using the 2017 <span>European League Against Rheumatism</span>/American College of Rheumatology Classification Criteria Open
Objective Inflammatory myopathies (IM), characterized by muscle inflammation and weakness, are rare systemic diseases. Our previous study estimated an IM incidence rate of 7.98 cases per million people per year (95% confidence interval 7.3…
View article: Paradoxical joint and muscle pain in a patient treated with anifrolumab and belimumab
Paradoxical joint and muscle pain in a patient treated with anifrolumab and belimumab Open
Data sharing is not applicable to this article as no new data were created or analysed in this study.
View article: Prognosis and long‐term outcomes in type I cryoglobulinemia: A multicenter study of 168 patients
Prognosis and long‐term outcomes in type I cryoglobulinemia: A multicenter study of 168 patients Open
Type I cryoglobulinemia (CG) accounts for 10%–15% of all cryoglobulinemias and are exclusively seen in clonal proliferative hematologic conditions. In this multicenter nationwide cohort study, we analyzed the prognosis and long‐term outcom…
View article: Supplementary Dataset from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary Dataset from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
List of genes and primers used
View article: Data from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Data from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
Purpose: Understanding tumor heterogeneity is an important challenge in current cancer research. Transcription and epigenetic profiling of cultured melanoma cells have defined at least two distinct cell phenotypes characterized by distinct…
View article: Supplementary information from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary information from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
Legends to Supplementary Figures and Dataset
View article: Supplementary Figure S5 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary Figure S5 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
RNAscope on sections from cutaneous metastasis
View article: Supplementary Figure S4 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary Figure S4 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
RNAscope on cultured MITF-high and MITF low cells
View article: Supplementary Figure S2 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary Figure S2 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
Comparison of gene expression in tumours 1 and 2
View article: Supplementary Dataset from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary Dataset from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
List of genes and primers used
View article: Supplementary Figure S2 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary Figure S2 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
Comparison of gene expression in tumours 1 and 2
View article: Supplementary Figure S6 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary Figure S6 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
SOX9 and SOX10 expression in sweat glands
View article: Supplementary Figure S3 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary Figure S3 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
Heatmaps of gene expression in tumours 3-5
View article: Supplementary Figure S1 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary Figure S1 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
Differential expression of MITF-high and MITF-low signature genes in cultured melanoma cells
View article: Supplementary information from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary information from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
Legends to Supplementary Figures and Dataset
View article: Supplementary Figure S6 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary Figure S6 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
SOX9 and SOX10 expression in sweat glands
View article: Supplementary Figure S4 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary Figure S4 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
RNAscope on cultured MITF-high and MITF low cells
View article: Supplementary Figure S3 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary Figure S3 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
Heatmaps of gene expression in tumours 3-5
View article: Supplementary Figure S1 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary Figure S1 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
Differential expression of MITF-high and MITF-low signature genes in cultured melanoma cells
View article: Data from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Data from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
Purpose: Understanding tumor heterogeneity is an important challenge in current cancer research. Transcription and epigenetic profiling of cultured melanoma cells have defined at least two distinct cell phenotypes characterized by distinct…
View article: Supplementary Figure S5 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma
Supplementary Figure S5 from <i>MITF</i>-High and <i>MITF</i>-Low Cells and a Novel Subpopulation Expressing Genes of Both Cell States Contribute to Intra- and Intertumoral Heterogeneity of Primary Melanoma Open
RNAscope on sections from cutaneous metastasis
View article: Similarities and differences in autoinflammatory diseases with urticarial rash, cryopyrin-associated periodic syndrome and Schnitzler syndrome
Similarities and differences in autoinflammatory diseases with urticarial rash, cryopyrin-associated periodic syndrome and Schnitzler syndrome Open
Cryopyrin-associated periodic syndromes (CAPS) and Schnitzler syndrome (SchS) are autoinflammatory diseases that present with urticaria-like rashes. CAPS is characterized by periodic or persistent systemic inflammation caused by the dysfun…
View article: Lack of response to midostaurin in a patient with vulvar melanoma harboring an unusual KIT D816Y mutation that emerged after a previous treatment with imatinib
Lack of response to midostaurin in a patient with vulvar melanoma harboring an unusual KIT D816Y mutation that emerged after a previous treatment with imatinib Open
To the Editor, Activating KIT mutations are frequent in vulvar melanoma and are mostly located in either exon 11 or 13 [[1]Wohlmuth C. Wohlmuth-Wieser I. Vulvar melanoma: molecular characteristics, diagnosis, surgical management, and medic…