Dana Kukje Zada
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View article: Gut substrate trap of D-lactate from microbiota improves blood glucose and fatty liver disease in obese mice
Gut substrate trap of D-lactate from microbiota improves blood glucose and fatty liver disease in obese mice Open
L-lactate participates in metabolism, including the Cori cycle, but less is known about D-lactate. We found that circulating D-lactate was higher in humans and mice with obesity. D-lactate increased hepatic glycogen, triglycerides, and blo…
View article: Microbiota protect against frailty and loss of skeletal muscle, and maintain inflammatory tone during aging in mice
Microbiota protect against frailty and loss of skeletal muscle, and maintain inflammatory tone during aging in mice Open
Germ-free mice had increased frailty, lower muscle mass, and lower circulating inflammatory monocytes. Therefore, lower systemic inflammation coincided with worse frailty and muscle loss. Microbial colonization decreased frailty, restored …
View article: 9171 Microbial D-lactate Contributes To Hyperglycemia During Obesity And Is A Potential Therapeutic Target
9171 Microbial D-lactate Contributes To Hyperglycemia During Obesity And Is A Potential Therapeutic Target Open
Disclosure: D. Kukje Zada: None. H. Fang: None. C. Gagnon: None. A. Tchernof: None. A. Marette: None. J. Schertzer: None. Metabolic disorders including obesity, type 2 diabetes, and metabolic dysfunction associated fatty liver disease (MAF…
View article: Postbiotic Impact on Host Metabolism and Immunity Provides Therapeutic Potential in Metabolic Disease
Postbiotic Impact on Host Metabolism and Immunity Provides Therapeutic Potential in Metabolic Disease Open
The gut microbiota influences aspects of metabolic disease, including tissue inflammation, adiposity, blood glucose, insulin, and endocrine control of metabolism. Prebiotics or probiotics are often sought to combat metabolic disease. Howev…
View article: An analysis of productivity app strengths: An environmental scan
An analysis of productivity app strengths: An environmental scan Open
BACKGROUNDIn recent years, productivity apps have become the most commonly used apps. While some may feel productivity apps work solely as a result of the placebo effect , productivity apps have been shown to have three major benefits: acc…
View article: Interventional procrastination strategies for young adults in virtual settings: A systematic review
Interventional procrastination strategies for young adults in virtual settings: A systematic review Open
BACKGROUNDThe phenomenon of academic procrastination affects nearly 95% of post-secondary students within academia with its association seen in reduced academic performance. Amidst the onset of COVID-19, this systematic review aims to prov…