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Supplementary Figure 3 from Genetic Variation That Predicts Platinum Sensitivity Reveals the Role of miR-193b* in Chemotherapeutic Susceptibility Open

Dana Ziliak, Eric R. Gamazon, Bonnie LaCroix, Hae Kyung Im, Yujia Wen , et al. · 2023

PDF file, 88K, The relationship between -log10GI50 of platinum agents and the expression of miR-193b* in 7 ovarian cancer cell lines.

Supplementary Figure 2 from Genetic Variation That Predicts Platinum Sensitivity Reveals the Role of miR-193b* in Chemotherapeutic Susceptibility Open

Dana Ziliak, Eric R. Gamazon, Bonnie LaCroix, Hae Kyung Im, Yujia Wen , et al. · 2023

PDF file, 90K, Graphical illustration of the relationships among the SNP rs1649942, 2 platinum-associated miRNAs and 5 platinum-associated target genes.

Data from Genetic Variation That Predicts Platinum Sensitivity Reveals the Role of miR-193b* in Chemotherapeutic Susceptibility Open

Dana Ziliak, Eric R. Gamazon, Bonnie LaCroix, Hae Kyung Im, Yujia Wen , et al. · 2023

Platinum agents are the backbone of cancer chemotherapy. Recently, we identified and replicated the role of a single nucleotide polymorphism (SNP, rs1649942) in predicting platinum sensitivity both in vitro and in vivo. Using…

Supplementary Figure 1 from Genetic Variation That Predicts Platinum Sensitivity Reveals the Role of miR-193b* in Chemotherapeutic Susceptibility Open

Dana Ziliak, Eric R. Gamazon, Bonnie LaCroix, Hae Kyung Im, Yujia Wen , et al. · 2023

PDF file, 65K, The Pearson correlation coefficient distribution of gene pairs.

Data from Genetic Variation That Predicts Platinum Sensitivity Reveals the Role of miR-193b* in Chemotherapeutic Susceptibility Open

Dana Ziliak, Eric R. Gamazon, Bonnie LaCroix, Hae Kyung Im, Yujia Wen , et al. · 2023

Platinum agents are the backbone of cancer chemotherapy. Recently, we identified and replicated the role of a single nucleotide polymorphism (SNP, rs1649942) in predicting platinum sensitivity both in vitro and in vivo. Using…

Supplementary Figure 1 from Genetic Variation That Predicts Platinum Sensitivity Reveals the Role of miR-193b* in Chemotherapeutic Susceptibility Open

Dana Ziliak, Eric R. Gamazon, Bonnie LaCroix, Hae Kyung Im, Yujia Wen , et al. · 2023

PDF file, 65K, The Pearson correlation coefficient distribution of gene pairs.

Supplementary Figure 3 from Genetic Variation That Predicts Platinum Sensitivity Reveals the Role of miR-193b* in Chemotherapeutic Susceptibility Open

Dana Ziliak, Eric R. Gamazon, Bonnie LaCroix, Hae Kyung Im, Yujia Wen , et al. · 2023

PDF file, 88K, The relationship between -log10GI50 of platinum agents and the expression of miR-193b* in 7 ovarian cancer cell lines.

Supplementary Figure Legend from Genetic Variation That Predicts Platinum Sensitivity Reveals the Role of miR-193b* in Chemotherapeutic Susceptibility Open

Dana Ziliak, Eric R. Gamazon, Bonnie LaCroix, Hae Kyung Im, Yujia Wen , et al. · 2023

PDF file, 57K.

Supplementary Figure Legend from Genetic Variation That Predicts Platinum Sensitivity Reveals the Role of miR-193b* in Chemotherapeutic Susceptibility Open

Dana Ziliak, Eric R. Gamazon, Bonnie LaCroix, Hae Kyung Im, Yujia Wen , et al. · 2023

PDF file, 57K.

Supplementary Figure 2 from Genetic Variation That Predicts Platinum Sensitivity Reveals the Role of miR-193b* in Chemotherapeutic Susceptibility Open

Dana Ziliak, Eric R. Gamazon, Bonnie LaCroix, Hae Kyung Im, Yujia Wen , et al. · 2023

PDF file, 90K, Graphical illustration of the relationships among the SNP rs1649942, 2 platinum-associated miRNAs and 5 platinum-associated target genes.

Supplementary Tables 1, 2 and 4 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open

R. Stephanie Huang, Sharon E. Johnatty, Eric R. Gamazon, Hae Kyung Im, Dana Ziliak , et al. · 2023

PDF file - 115K

Supplementary Tables 1, 2 and 4 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open

R. Stephanie Huang, Sharon E. Johnatty, Eric R. Gamazon, Hae Kyung Im, Dana Ziliak , et al. · 2023

PDF file - 115K

Supplementary Table 3 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open

R. Stephanie Huang, Sharon E. Johnatty, Eric R. Gamazon, Hae Kyung Im, Dana Ziliak , et al. · 2023

PDF - 76K

Supplementary Figures 1-3 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open

R. Stephanie Huang, Sharon E. Johnatty, Eric R. Gamazon, Hae Kyung Im, Dana Ziliak , et al. · 2023

PDF file - 263K

Data from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open

R. Stephanie Huang, Sharon E. Johnatty, Eric R. Gamazon, Hae Kyung Im, Dana Ziliak , et al. · 2023

Purpose: Cell-based approaches were used to identify genetic markers predictive of patients' risk for poor response prior to chemotherapy.Experimental Design: We conducted genome-wide association studies (GWAS) to identify si…

Supplementary Table 3 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open

R. Stephanie Huang, Sharon E. Johnatty, Eric R. Gamazon, Hae Kyung Im, Dana Ziliak , et al. · 2023

PDF - 76K

Supplementary Figures 1-3 from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open

R. Stephanie Huang, Sharon E. Johnatty, Eric R. Gamazon, Hae Kyung Im, Dana Ziliak , et al. · 2023

PDF file - 263K

Data from Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients Open

R. Stephanie Huang, Sharon E. Johnatty, Eric R. Gamazon, Hae Kyung Im, Dana Ziliak , et al. · 2023

Purpose: Cell-based approaches were used to identify genetic markers predictive of patients' risk for poor response prior to chemotherapy.Experimental Design: We conducted genome-wide association studies (GWAS) to identify si…

Utility of patient-derived lymphoblastoid cell lines as an <i>ex vivo</i> capecitabine sensitivity prediction model for breast cancer patients Open

Gladys Morrison, Divya Lenkala, Bonnie LaCroix, Dana Ziliak, Vandana G. Abramson , et al. · 2016

Capecitabine is commonly used in treating breast cancer; however, therapeutic response varies among patients and there is no clinically validated model to predict individual outcomes. Here, we investigated whether drug sensitivity quantifi…

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