Dandan Zheng
YOU?
Author Swipe
View article: Stereotactic radiosurgery for patients with 5 or more brain metastases: Retrospective single-institution analysis with focus on brain metastasis velocity
Stereotactic radiosurgery for patients with 5 or more brain metastases: Retrospective single-institution analysis with focus on brain metastasis velocity Open
Purpose We describe patient outcomes following linear accelerator-based stereotactic radiosurgery (SRS) for ≥ 5 brain metastases, without prior or planned whole-brain radiotherapy. Methods We identified 116 eligible patients treated with S…
View article: Ming-UniVision: Joint Image Understanding and Generation with a Unified Continuous Tokenizer
Ming-UniVision: Joint Image Understanding and Generation with a Unified Continuous Tokenizer Open
Visual tokenization remains a core challenge in unifying visual understanding and generation within the autoregressive paradigm. Existing methods typically employ tokenizers in discrete latent spaces to align with the tokens from large lan…
View article: Effectiveness of emotional freedom techniques therapy in alleviating anticipatory grief for cancer patients
Effectiveness of emotional freedom techniques therapy in alleviating anticipatory grief for cancer patients Open
Background: Cancer patients frequently experience anticipatory grief (AG), anxiety, and sleep disturbances. This randomized controlled trial evaluates the efficacy of the emotional freedom technique (EFT) therapy in alleviating these sympt…
View article: Organizing pneumonia in ALK+ non-small cell lung cancer treated with ceritinib: a case report
Organizing pneumonia in ALK+ non-small cell lung cancer treated with ceritinib: a case report Open
OP should be considered when new lesions appear in the lungs of lung cancer patients, and distinguished from infectious pneumonia, metastasis, or cancer progression. In this respect, pathological biopsy plays an important role in diagnosis…
View article: VideoMAR: Autoregressive Video Generatio with Continuous Tokens
VideoMAR: Autoregressive Video Generatio with Continuous Tokens Open
Masked-based autoregressive models have demonstrated promising image generation capability in continuous space. However, their potential for video generation remains under-explored. In this paper, we propose \textbf{VideoMAR}, a concise an…
View article: New Approaches in Radiotherapy
New Approaches in Radiotherapy Open
Radiotherapy (RT) has undergone transformative advancements since its inception over a century ago. This review highlights the most promising and impactful innovations shaping the current and future landscape of RT. Key technological advan…
View article: AAPM Task Group No. 249.B—Essentials and guidelines for clinical medical physics residency training programs
AAPM Task Group No. 249.B—Essentials and guidelines for clinical medical physics residency training programs Open
The establishment of guidelines and curriculum standards for medical physics residency training is a critical component of setting expectations and competencies for the profession. Since the last publication of these standards, residency t…
View article: Clinical Practice-Based Failure Modes and Root Cause Analysis of Cone Beam CT-Guided Online Adaptive Radiotherapy of the Pelvis
Clinical Practice-Based Failure Modes and Root Cause Analysis of Cone Beam CT-Guided Online Adaptive Radiotherapy of the Pelvis Open
Background/Objectives: Cone-beam computed tomography (CBCT)-guided online adaptive radiotherapy (oART) represents a significant advancement in radiation oncology, enabling on-couch plan adaptation to account for daily anatomical changes. W…
View article: Methods for working with problem residents in medical physics residency education
Methods for working with problem residents in medical physics residency education Open
Medical physics residency training programs may occasionally encounter residents requiring additional intervention beyond normal training efforts. In the literature, these residents are referred to as “problem” residents. While the physici…
View article: MR‐Linac is a better choice for adaptive therapy compared to cone‐beam CT
MR‐Linac is a better choice for adaptive therapy compared to cone‐beam CT Open
View article: The cryptic lncRNA-encoded microprotein TPM3P9 drives oncogenic RNA splicing and tumorigenesis
The cryptic lncRNA-encoded microprotein TPM3P9 drives oncogenic RNA splicing and tumorigenesis Open
Emerging evidence demonstrates that cryptic translation from RNAs previously annotated as noncoding might generate microproteins with oncogenic functions. However, the importance and underlying mechanisms of these microproteins in alternat…
View article: Intra-Arterial Urokinase After Endovascular Reperfusion for Acute Ischemic Stroke
Intra-Arterial Urokinase After Endovascular Reperfusion for Acute Ischemic Stroke Open
Importance Persisting or new thrombi in the distal arteries and the microcirculation have been reported to limit the benefits of successful endovascular thrombectomy for patients with acute ischemic stroke. It remains uncertain whether int…
View article: Identification of the Core Nutrition Impact Symptoms Cluster in Patients with Lung Cancer During Chemotherapy: A Symptom Network Analysis
Identification of the Core Nutrition Impact Symptoms Cluster in Patients with Lung Cancer During Chemotherapy: A Symptom Network Analysis Open
Nurses need to comprehensively consider the interaction of multidimensional symptoms to provide lung chemotherapy cancer with targeted symptom management strategies and intervention guidance to reduce the burden of symptoms and improve qua…
View article: Shikonin Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis to Attenuate Renal Ischemia/Reperfusion Injury by Activating the Sirt1/Nrf2/HO-1 Pathway
Shikonin Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis to Attenuate Renal Ischemia/Reperfusion Injury by Activating the Sirt1/Nrf2/HO-1 Pathway Open
Introduction: Shikonin is the major bioactive compound abundant in Lithospermum erythrorhizon and possesses diverse pharmacological properties. This study aimed to examine shikonin roles in experimental renal ischemia/reperfusion (I/R) inj…
View article: Development and validation of AI delineation of the thoracic RTOG organs at risk with deep learning on multi-institutional datasets
Development and validation of AI delineation of the thoracic RTOG organs at risk with deep learning on multi-institutional datasets Open
View article: KDM2B regulates stroke injury by modulating OGT-mediated 0-GlcNAcylation of SLC7A11
KDM2B regulates stroke injury by modulating OGT-mediated 0-GlcNAcylation of SLC7A11 Open
View article: Comparative analysis of fetal dose sparing between a C‐arm linac and an O‐ring linac in a SIB‐VMAT sarcoma treatment for a pregnant patient: A technical note and case report
Comparative analysis of fetal dose sparing between a C‐arm linac and an O‐ring linac in a SIB‐VMAT sarcoma treatment for a pregnant patient: A technical note and case report Open
Purpose To compare the effect of two linacs designs on fetal dose sparing on a pregnant patient, including estimation of the fetal dose, and the effect of a lead apron. Methods A patient with a high‐grade sarcoma located in the right knee/…
View article: <scp>PPM1G</scp>‐mediated <scp>TBL1X mRNA</scp> splicing promotes cell migration in hepatocellular carcinoma
<span>PPM1G</span>‐mediated <span>TBL1X mRNA</span> splicing promotes cell migration in hepatocellular carcinoma Open
The progression of hepatocellular carcinoma (HCC) is coincident with aberrant splicing of numerous tumor‐related genes. Identification of the tumor‐specific splice variants that facilitate HCC metastasis may provide a more comprehensive in…
View article: The Application of Six Sigma Management Theory in Service Industry
The Application of Six Sigma Management Theory in Service Industry Open
Since it was first introduced by Motorola in the late 20th century, Six Sigma management theory has risen rapidly and become a key strategy for many enterprises to improve quality management and core competitiveness. Based on the definitio…
View article: MU variability in CBCT‐guided online adaptive radiation therapy
MU variability in CBCT‐guided online adaptive radiation therapy Open
Purpose CBCT‐guided online‐adaptive radiotherapy (oART) systems have been made possible by using artificial intelligence and automation to substantially reduce treatment planning time during on‐couch adaptive sessions. Evaluating plans gen…
View article: Association Between EEG Power During Sleep and Attention Levels in Patients with Major Depressive Disorder
Association Between EEG Power During Sleep and Attention Levels in Patients with Major Depressive Disorder Open
Our findings suggest that patients with MDD manifest impaired selective attention function that is associated with decreased theta power during NREM/REM sleep and increased delta power during REM sleep.
View article: radioGWAS links radiome to genome to discover driver genes with somatic mutations for heterogeneous tumor image phenotype in pancreatic cancer
radioGWAS links radiome to genome to discover driver genes with somatic mutations for heterogeneous tumor image phenotype in pancreatic cancer Open
Addressing the significant level of variability exhibited by pancreatic cancer necessitates the adoption of a systems biology approach that integrates molecular data, biological properties of the tumors, medical images, and clinical featur…
View article: Immune cell patterns before and after neoadjuvant immune checkpoint blockade combined with chemoradiotherapy in locally advanced esophageal squamous cell carcinoma
Immune cell patterns before and after neoadjuvant immune checkpoint blockade combined with chemoradiotherapy in locally advanced esophageal squamous cell carcinoma Open
View article: Case study with dosimetric analysis: Total body irradiation to a patient with a left ventricular assist device
Case study with dosimetric analysis: Total body irradiation to a patient with a left ventricular assist device Open
Key Clinical Message A patient presented with cardiogenic shock, requiring the implantation of a left ventricular assist device (LVAD), and acute myeloblastic leukemia. This necessitated total body irradiation (TBI) while balancing dose re…
View article: Teaching Physicists Effective Patient Communication Through eLearning
Teaching Physicists Effective Patient Communication Through eLearning Open
This is a published abstract from the UNMC Spotlight on Scholarship 2022.
View article: Case study with dosimetric analysis: Total Body irradiation to a patient with a left ventricular assist device
Case study with dosimetric analysis: Total Body irradiation to a patient with a left ventricular assist device Open
Purpose: This case report discusses the safe delivery of total body irradiation (TBI) to a patient with a left ventricular assist device (LVAD).This treatment required radiation-dose determinations and consequential reductions for the hear…
View article: Adaptive Radiotherapy: Next-Generation Radiotherapy
Adaptive Radiotherapy: Next-Generation Radiotherapy Open
Radiotherapy, a crucial technique in cancer therapy, has traditionally relied on the premise of largely unchanging patient anatomy during the treatment course and encompassing uncertainties by target margins. This review introduces adaptiv…
View article: How Does the Number of Brain Metastases Correlate With Normal Brain Exposure in Single-Isocenter Multitarget Multifraction Stereotactic Radiosurgery
How Does the Number of Brain Metastases Correlate With Normal Brain Exposure in Single-Isocenter Multitarget Multifraction Stereotactic Radiosurgery Open
View article: Dosimetric evaluation of LINAC-based single-isocenter multi-target multi-fraction stereotactic radiosurgery with more than 20 targets: comparing MME, HyperArc, and RapidArc
Dosimetric evaluation of LINAC-based single-isocenter multi-target multi-fraction stereotactic radiosurgery with more than 20 targets: comparing MME, HyperArc, and RapidArc Open
Background To compare the dosimetric quality of three widely used techniques for LINAC-based single-isocenter multi-target multi-fraction stereotactic radiosurgery (fSRS) with more than 20 targets: dynamic conformal arc (DCA) in BrainLAB M…
View article: Immune cell patterns before and after neoadjuvant immune checkpoint blockade combined with chemoradiotherapy in locally advanced esophageal squamous cell carcinoma
Immune cell patterns before and after neoadjuvant immune checkpoint blockade combined with chemoradiotherapy in locally advanced esophageal squamous cell carcinoma Open
Background: Neoadjuvant immune checkpoint blockade (ICB) combined with chemoradiotherapy offers high pathologic complete response (pCR) rate for patients with locally advanced esophageal squamous cell carcinomas (ESCC). But the dynamic tum…