Daniel A. Hu
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View article: 2022 MRC-ARL Summer Student Team Research Experience: Air-Deployed Robots for Mobile Sensing
2022 MRC-ARL Summer Student Team Research Experience: Air-Deployed Robots for Mobile Sensing Open
Their mission centered on the conception and construction of a system for the airdrop deployment of a ground-based robot.This was motivated by the quest for safer, more efficient alternatives to current methods of delivering critical suppl…
View article: Immune-Related Long Non-Coding RNA Signatures for Tongue Squamous Cell Carcinoma
Immune-Related Long Non-Coding RNA Signatures for Tongue Squamous Cell Carcinoma Open
Background: Tongue squamous cell carcinoma (TSCC) represents one of the major subsets of head and neck cancer, which is characterized by unfavorable prognosis, frequent lymph node metastasis, and high mortality rate. The molecular events r…
View article: A Tool for Low-Cost, Quantitative Assessment of Shoulder Function Using Machine Learning
A Tool for Low-Cost, Quantitative Assessment of Shoulder Function Using Machine Learning Open
Tears within the stabilizing muscles of the shoulder, known as the rotator cuff (RC), are the most common cause of shoulder pain—often presenting in older patients and requiring expensive, advanced imaging for diagnosis 1–4 . Despite the h…
View article: Melanoma: Molecular genetics, metastasis, targeted therapies, immunotherapies, and therapeutic resistance
Melanoma: Molecular genetics, metastasis, targeted therapies, immunotherapies, and therapeutic resistance Open
Cutaneous melanoma is a common cancer and cases have steadily increased since the mid 70s. For some patients, early diagnosis and surgical removal of melanomas is lifesaving, while other patients typically turn to molecular targeted therap…
View article: Dyslipidemia is associated with risk for rotator cuff repair failure: a systematic review and meta-analysis
Dyslipidemia is associated with risk for rotator cuff repair failure: a systematic review and meta-analysis Open
DLD leads to an increased risk of retear after rotator cuff repair, although function appears to be unimpaired. DLD should be considered among other risk factors when counseling patients regarding expected rotator cuff repair outcomes.
View article: OUHP: an optimized universal hairpin primer system for cost-effective and high-throughput RT-qPCR-based quantification of microRNA (miRNA) expression
OUHP: an optimized universal hairpin primer system for cost-effective and high-throughput RT-qPCR-based quantification of microRNA (miRNA) expression Open
MicroRNAs (miRNAs or miRs) are single-stranded, ∼22-nucleotide noncoding RNAs that regulate many cellular processes. While numerous miRNA quantification technologies are available, a recent analysis of 12 commercial platforms revealed high…
View article: What Factors Lead to Racial Disparities in Outcomes After Total Knee Arthroplasty?
What Factors Lead to Racial Disparities in Outcomes After Total Knee Arthroplasty? Open
Total knee arthroplasty (TKA) is one of the most commonly performed, major elective surgeries in the USA. African American TKA patients on average experience worse clinical outcomes than whites, including lower improvements in patient-repo…
View article: Patient-Reported Outcomes After Total Hip Arthroplasty in a Low-Resource Country by a Visiting Surgical Team
Patient-Reported Outcomes After Total Hip Arthroplasty in a Low-Resource Country by a Visiting Surgical Team Open
Patients in low-resource countries benefitted significantly from THA performed by a visiting surgical team. However, following up patients is difficult in low-resource countries once they leave the hospital.
View article: Applications of Biocompatible Scaffold Materials in Stem Cell-Based Cartilage Tissue Engineering
Applications of Biocompatible Scaffold Materials in Stem Cell-Based Cartilage Tissue Engineering Open
Cartilage, especially articular cartilage, is a unique connective tissue consisting of chondrocytes and cartilage matrix that covers the surface of joints. It plays a critical role in maintaining joint durability and mobility by providing …
View article: Identification of prognostic signature based on the copy number variation (CNV) and expression in acute myeloid leukemia
Identification of prognostic signature based on the copy number variation (CNV) and expression in acute myeloid leukemia Open
Background Acute myeloid leukemia (AML) is caused by multiple genetic alterations in the hematopoietic progenitors, and molecular genetic analysis has provided useful information for AML diagnosis and prognosis. However, an integrative und…
View article: Identification of a prognostic signature based on copy number variations (CNVs) and CNV-modulated gene expression in acute myeloid leukemia.
Identification of a prognostic signature based on copy number variations (CNVs) and CNV-modulated gene expression in acute myeloid leukemia. Open
Overall, this study identified 102 CNV-related genes associated with patient survival and identified five genes whose expression was modulated by CNVs and associated with patient survival. Our findings are crucial for the development of ne…
View article: Stem Cell-Friendly Scaffold Biomaterials: Applications for Bone Tissue Engineering and Regenerative Medicine
Stem Cell-Friendly Scaffold Biomaterials: Applications for Bone Tissue Engineering and Regenerative Medicine Open
Bone is a dynamic organ with high regenerative potential and provides essential biological functions in the body, such as providing body mobility and protection of internal organs, regulating hematopoietic cell homeostasis, and serving as …
View article: Comparison of Patient-Reported Outcomes for Major Pathologies of the Forefoot, Midfoot, Hindfoot, and Achilles Using PROMIS
Comparison of Patient-Reported Outcomes for Major Pathologies of the Forefoot, Midfoot, Hindfoot, and Achilles Using PROMIS Open
Background: Patient-Reported Outcomes Measurement Information System (PROMIS) is a newly developed patient-reported outcome that has been validated for the general foot and ankle population and has been applied to a variety of specific foo…
View article: Comparison of Patient Reported Outcomes (PROs) for Major Pathologies of the Forefoot, Midfoot, Hindfoot, and Achilles Using PROMIS
Comparison of Patient Reported Outcomes (PROs) for Major Pathologies of the Forefoot, Midfoot, Hindfoot, and Achilles Using PROMIS Open
Category: Other; Hindfoot; Midfoot/Forefoot Introduction/Purpose: Many legacy patient reported outcomes (PROs) lack sufficient validity and reliability for the evaluation of clinical outcomes following foot and ankle procedures. Patient-Re…
View article: Identification of Prognostic Signature Based on the Copy Number Variation (CNV) and Expression in Acute Myeloid Leukemia
Identification of Prognostic Signature Based on the Copy Number Variation (CNV) and Expression in Acute Myeloid Leukemia Open
Purpose Acute myeloid leukemia (AML) is caused by multiple genetic alterations in the hematopoietic progenitors, and molecular genetic analysis has provided useful information for AML diagnosis and prognosis. However, an integrative unders…