Daniel Berner
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View article: Developmental genetic basis of dorsal spine reduction in acidic-adapted threespine stickleback fish
Developmental genetic basis of dorsal spine reduction in acidic-adapted threespine stickleback fish Open
The repeated evolution of reduced skeletal armour in threespine stickleback provides an excellent model for understanding the genetic basis of morphological change. Here, we investigated the genetic and developmental mechanisms underlying …
View article: <scp>PROCEED</scp> v6.1: Phenotypic rates of change evolutionary and ecological database
<span>PROCEED</span> v6.1: Phenotypic rates of change evolutionary and ecological database Open
Populations must continuously respond to environmental change or risk extinction. These responses can be measured as phenotypic rates of change, which allow researchers to predict their contemporary evolutionary responses. In 1999, a datab…
View article: Joint analysis of germline genetic data from over 29,000 cases with suspected hereditary breast and ovarian cancer (HBOC) as part of the NASGE initiative
Joint analysis of germline genetic data from over 29,000 cases with suspected hereditary breast and ovarian cancer (HBOC) as part of the NASGE initiative Open
As multigene panel testing is becoming routine in clinical care, there are recommendations at national and international level, as to which genes should be analyzed in the context of a hereditary breast and ovarian cancer (HBOC). However, …
View article: Referee report. For: The genome sequence of the Twenty-plume Moth, Alucita hexadactyla Linnaeus, 1758 [version 1; peer review: 1 approved, 1 approved with reservations]
Referee report. For: The genome sequence of the Twenty-plume Moth, Alucita hexadactyla Linnaeus, 1758 [version 1; peer review: 1 approved, 1 approved with reservations] Open
View article: Urbanization-associated range expansion genetically homogenizes a butterfly species
Urbanization-associated range expansion genetically homogenizes a butterfly species Open
Human-induced environmental change and globalization facilitate biological invasions, which can lead to the displacement of native species by non-native ones.1,2,3,4
View article: Invasion of Pieris mannii butterflies across Central Europe facilitated by urbanization
Invasion of Pieris mannii butterflies across Central Europe facilitated by urbanization Open
Urbanization progresses world-wide and the frequency of biological invasions increases. Understanding to what extent urban environments facilitate biological invasions and how this affects ecosystems within and outside urbanized areas thus…
View article: Code and data underlying the Ruffener et al. 2024 study on habitat use in Pieris mannii butterflies
Code and data underlying the Ruffener et al. 2024 study on habitat use in Pieris mannii butterflies Open
Code compilation (R language) and data sets used to generate all graphics and other analyses presented in Ruffener et al. 2024. An overview of the codes is given in the beginning of the code compilation (CodeCollectionRuffenerEtAl2024.txt)…
View article: Referee report. For: The genome sequence of the Rock Grayling, Hipparchia semele (Linnaeus, 1758) [version 1; peer review: 2 approved]
Referee report. For: The genome sequence of the Rock Grayling, Hipparchia semele (Linnaeus, 1758) [version 1; peer review: 2 approved] Open
View article: Referee report. For: The genome sequence of the Fan-foot, Herminia tarsipennalis (Treitschke, 1835) [version 1; peer review: 1 approved, 1 approved with reservations]
Referee report. For: The genome sequence of the Fan-foot, Herminia tarsipennalis (Treitschke, 1835) [version 1; peer review: 1 approved, 1 approved with reservations] Open
View article: Invasion of Pieris mannii butterflies across Central Europe facilitated by urbanization
Invasion of Pieris mannii butterflies across Central Europe facilitated by urbanization Open
Urbanization progresses world-wide and the frequency of biological invasions increases. Understanding to what extent urban environments facilitate biological invasions and how this affects ecosystems within and outside urbanized areas thus…
View article: Chromosome-Level Assemblies of the <i>Pieris mannii</i> Butterfly Genome Suggest Z-Origin and Rapid Evolution of the W Chromosome
Chromosome-Level Assemblies of the <i>Pieris mannii</i> Butterfly Genome Suggest Z-Origin and Rapid Evolution of the W Chromosome Open
The insect order Lepidoptera (butterflies and moths) represents the largest group of organisms with ZW/ZZ sex determination. While the origin of the Z chromosome predates the evolution of the Lepidoptera, the W chromosomes are considered y…
View article: Quality assurance within the context of genome diagnostics (a german perspective)
Quality assurance within the context of genome diagnostics (a german perspective) Open
The rapid and dynamic implementation of Next-Generation Sequencing (NGS)-based assays has revolutionized genetic testing, and in the near future, nearly all molecular alterations of the human genome will be diagnosable via massive parallel…
View article: Chromosome-level assemblies of the<i>Pieris mannii</i>butterfly genome suggest Z-origin and rapid evolution of the W chromosome
Chromosome-level assemblies of the<i>Pieris mannii</i>butterfly genome suggest Z-origin and rapid evolution of the W chromosome Open
The insect order Lepidoptera (butterflies and moth) represents the largest group of organisms with ZW/ZZ sex determination. While the origin of the Z chromosome predates the evolution of the Lepidoptera, the W chromosome is considered youn…
View article: Analysis of genetically determined gene expression suggests role of inflammatory processes in exfoliation syndrome
Analysis of genetically determined gene expression suggests role of inflammatory processes in exfoliation syndrome Open
Background Exfoliation syndrome (XFS) is an age-related systemic disorder characterized by excessive production and progressive accumulation of abnormal extracellular material, with pathognomonic ocular manifestations. It is the most commo…
View article: Dysregulated Retinoic Acid Signaling in the Pathogenesis of Pseudoexfoliation Syndrome
Dysregulated Retinoic Acid Signaling in the Pathogenesis of Pseudoexfoliation Syndrome Open
Pseudoexfoliation (PEX) syndrome, a stress-induced fibrotic matrix process, is the most common recognizable cause of open-angle glaucoma worldwide. The recent identification of PEX-associated gene variants uncovered the vitamin A metabolic…
View article: Why and how we should join the shift from significance testing to estimation
Why and how we should join the shift from significance testing to estimation Open
A paradigm shift away from null hypothesis significance testing seems in progress. Based on simulations, we illustrate some of the underlying motivations. First, p ‐values vary strongly from study to study, hence dichotomous inference usin…
View article: The ectodysplasin-A receptor is a candidate gene for lateral plate number variation in stickleback fish
The ectodysplasin-A receptor is a candidate gene for lateral plate number variation in stickleback fish Open
Variation in lateral plating in stickleback fish represents a classical example of rapid and parallel adaptation in morphology. The underlying genetic architecture involves polymorphism at the ectodysplasin-A gene (EDA). However, lateral p…
View article: Why and How We Should Join the Shift From Significance Testing to Estimation
Why and How We Should Join the Shift From Significance Testing to Estimation Open
A paradigm shift away from null hypothesis significance testing seems in progress. Based on simulations, we illustrate some of the underlying motivations. First, P-values vary strongly from study to study, hence dichotomous inference using…
View article: Intra‐Alpine Islands: Population genomic inference reveals high degree of isolation between freshwater spring habitats
Intra‐Alpine Islands: Population genomic inference reveals high degree of isolation between freshwater spring habitats Open
Aim Alpine spring ecosystems have long been considered as highly isolated, island‐like habitats. This presumption, however, is insufficiently supported empirically and conclusions about spring isolation have been based on indirect evidence…
View article: Why and How We Should Join the Shift From Significance Testing to Estimation
Why and How We Should Join the Shift From Significance Testing to Estimation Open
A paradigm shift away from null hypothesis significance testing seems in progress. Based on simulations, we illustrate some of the underlying motivations. First, P-values vary strongly from study to study, hence dichotomous inference using…
View article: The maintenance of standing genetic variation: Gene flow vs. selective neutrality in Atlantic stickleback fish
The maintenance of standing genetic variation: Gene flow vs. selective neutrality in Atlantic stickleback fish Open
Adaptation to derived habitats often occurs from standing genetic variation. The maintenance within ancestral populations of genetic variants favourable in derived habitats is commonly ascribed to long‐term antagonism between purifying sel…
View article: Clinal genomic analysis reveals strong reproductive isolation across a steep habitat transition in stickleback fish
Clinal genomic analysis reveals strong reproductive isolation across a steep habitat transition in stickleback fish Open
View article: The maintenance of standing genetic variation: gene flow versus selective neutrality in Atlantic stickleback fish
The maintenance of standing genetic variation: gene flow versus selective neutrality in Atlantic stickleback fish Open
Adaptation to derived habitats often occurs from standing genetic variation (SGV). The maintenance within ancestral populations of genetic variants favorable in derived habitats is commonly ascribed to long-term antagonism between purifyin…
View article: Gestaltung einer arbeitsplatznahen und multifunktionalen Lernumgebung
Gestaltung einer arbeitsplatznahen und multifunktionalen Lernumgebung Open
Bestehende Kompetenzen von Mitarbeitenden werden durch fortlaufende Veränderungen der Arbeitswelt auf den Prüfstand gestellt. Eine möglichst praxisnahe und bedarfsspezifische Weiterbildung hilft, mit den neu entstehenden Anforderungen erfo…
View article: Re-evaluating the evidence for facilitation of stickleback speciation by admixture in the Lake Constance basin
Re-evaluating the evidence for facilitation of stickleback speciation by admixture in the Lake Constance basin Open
View article: Analysis of Genetically Determined Gene Expression Suggests Role of Inflammatory Processes in Exfoliation Syndrome
Analysis of Genetically Determined Gene Expression Suggests Role of Inflammatory Processes in Exfoliation Syndrome Open
Exfoliation syndrome (XFS) is an age-related systemic disorder characterized by excessive production and progressive accumulation of abnormal extracellular material, with pathognomonic ocular manifestations. It is the most common cause of …
View article: Clinal genomic analysis reveals strong reproductive isolation across a steep habitat transition in stickleback fish
Clinal genomic analysis reveals strong reproductive isolation across a steep habitat transition in stickleback fish Open
How ecological divergence causes strong reproductive isolation between populations in close geographic contact remains poorly understood at the genomic level. We here study this question in a stickleback population pair adapted to contiguo…
View article: Analysis of Genetically Determined Gene Expression Suggests Role of Inflammatory Processes in Etiology of Exfoliation Syndrome
Analysis of Genetically Determined Gene Expression Suggests Role of Inflammatory Processes in Etiology of Exfoliation Syndrome Open
Exfoliation syndrome (XFS) is an age-related systemic disorder characterized by excessive production and progressive accumulation of abnormal extracellular material, with pathognomonic ocular manifestations. It is the most common cause of …
View article: Analysis of genetically determined gene expression suggest role of inflammatory processes in etiology of exfoliation syndrome
Analysis of genetically determined gene expression suggest role of inflammatory processes in etiology of exfoliation syndrome Open
View article: Speciation in Stickleback Facilitated by Admixture &ndash; Where is the Evidence?
Speciation in Stickleback Facilitated by Admixture – Where is the Evidence? Open
Where genetic variation promoting speciation originates is a crucial question in evolutionary genomics. In a recent article, Marques et al. (2019) seek to address this question in lake and stream threespine stickleback fish from the Lake C…