Daniel Dosoo
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View article: Plasmodium falciparum Subtilisin-like Domain-Containing Protein (PfSDP), a Cross-Stage Antigen, Elicits Short-Lived Antibody Response Following Natural Infection with Plasmodium falciparum
Plasmodium falciparum Subtilisin-like Domain-Containing Protein (PfSDP), a Cross-Stage Antigen, Elicits Short-Lived Antibody Response Following Natural Infection with Plasmodium falciparum Open
With the increasing detection of artemisinin resistance to front-line antimalarials in Africa and notwithstanding the planned roll-out of RTS’S and R21 in Africa, the search for new vaccines with high efficacy remains an imperative. Toward…
View article: <i>Plasmodium falciparum</i> isolates: <i>ex vivo</i> drug response
<i>Plasmodium falciparum</i> isolates: <i>ex vivo</i> drug response Open
Objectives While artemisinin-based combination therapies (ACTs) are effective in sub-Saharan Africa, clinical isolates that are refractory to artemisinin derivatives are emerging in East Africa and ACT partner drugs are becoming less effec…
View article: <em>Plasmodium falciparum</em> Subtilisin-Like Domain Containing Protein ((PfSDP) PF3D7_1105800), a Cross-Stage Antigen, Elicits Short-Lived Antibody Response Following Natural Infection with <em>Plasmodium falciparum</em>
<em>Plasmodium falciparum</em> Subtilisin-Like Domain Containing Protein ((PfSDP) PF3D7_1105800), a Cross-Stage Antigen, Elicits Short-Lived Antibody Response Following Natural Infection with <em>Plasmodium falciparum</em> Open
With the increasing detection of artemisinin resistance to front-line antimalarials in Africa and notwithstanding the planned roll-out of RTS’S and R21 in Africa, the search for new vaccines with high efficacy remains an imperative. Toward…
View article: MMV006087 is a potent Malaria Box compound against Plasmodium falciparum clinical parasites
MMV006087 is a potent Malaria Box compound against Plasmodium falciparum clinical parasites Open
The emergence of drug-resistant malaria parasites to artemisinin and its partner drugs highlights the need to increase the arsenal of new antimalarials with novel mechanisms of action. To help achieve this aim, this study tested the potenc…