Daniel Eibach
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View article: Two-stage cluster sampling to assess SARS-CoV-2 seroprevalence without pre-enumeration: An example from Madagascar
Two-stage cluster sampling to assess SARS-CoV-2 seroprevalence without pre-enumeration: An example from Madagascar Open
Implementing population-based surveys in resource-constrained settings presents logistical challenges when detailed population enumeration is unavailable. We developed a field mapping system integrated into a cluster sampling approach to e…
View article: Modeling pediatric antibiotic use in an area of declining malaria prevalence
Modeling pediatric antibiotic use in an area of declining malaria prevalence Open
In malaria-endemic areas of Sub-Saharan Africa, overlap of clinical symptoms between malarial and non-malarial febrile illnesses can lead to empiric use of antibiotics among children. Our study aimed to illustrate the potential impact of d…
View article: Fever in focus: Symptoms, diagnoses and treatment of febrile children in Ghana—A longitudinal hospital study
Fever in focus: Symptoms, diagnoses and treatment of febrile children in Ghana—A longitudinal hospital study Open
Background Healthcare resources are often limited in areas of sub‐Saharan Africa. This makes accurate and timely diagnoses challenging and delays treatment of childhood febrile illness. We explored longitudinal characteristics related to s…
View article: Dataset and R script: a longitudinal hospital study of febrile children in Ghana
Dataset and R script: a longitudinal hospital study of febrile children in Ghana Open
This is the dataset and R script accompanying the manuscript "Fever in focus: symptoms, diagnoses, and treatment of febrile children in Ghana, a longitudinal hospital study."
View article: Dataset and R script: a longitudinal hospital study of febrile children in Ghana
Dataset and R script: a longitudinal hospital study of febrile children in Ghana Open
This is the dataset and R script accompanying the manuscript "Fever in focus: symptoms, diagnoses, and treatment of febrile children in Ghana, a longitudinal hospital study."
View article: Prevalence, Characterization, and Antimicrobial Resistance of Extended-Spectrum Beta-Lactamase-Producing <i>Escherichia coli</i> from Domestic Free-Range Poultry in Agogo, Ghana
Prevalence, Characterization, and Antimicrobial Resistance of Extended-Spectrum Beta-Lactamase-Producing <i>Escherichia coli</i> from Domestic Free-Range Poultry in Agogo, Ghana Open
Poultry has been suggested as an important source for extended-spectrum beta-lactamase (ESBL)-producing bacteria that can lead to difficult-to treat infections in humans. Therefore, this study aims to determine the frequency, the genetics,…
View article: The person-to-person transmission landscape of the gut and oral microbiomes
The person-to-person transmission landscape of the gut and oral microbiomes Open
The human microbiome is an integral component of the human body and a co-determinant of several health conditions 1,2 . However, the extent to which interpersonal relations shape the individual genetic makeup of the microbiome and its tran…
View article: Laboratory-based surveillance of antimicrobial resistance in regions of Kenya: An assessment of capacities, practices, and barriers by means of multi-facility survey
Laboratory-based surveillance of antimicrobial resistance in regions of Kenya: An assessment of capacities, practices, and barriers by means of multi-facility survey Open
Background Adequate laboratory capacity is critical in the implementation of coherent surveillance for antimicrobial resistance (AMR). We describe capacities and deficiencies in laboratory infrastructure and AMR surveillance practices amon…
View article: High seroprevalence of SARS-CoV-2 in Burkina-Faso, Ghana and Madagascar in 2021: a population-based study
High seroprevalence of SARS-CoV-2 in Burkina-Faso, Ghana and Madagascar in 2021: a population-based study Open
Background The current COVID-19 pandemic affects the entire world population and has serious health, economic and social consequences. Assessing the prevalence of COVID-19 through population-based serological surveys is essential to monito…
View article: Clustering of Cryptosporidium species infections among sheep and cattle but not children in remote highland communities of Madagascar
Clustering of Cryptosporidium species infections among sheep and cattle but not children in remote highland communities of Madagascar Open
Background The aim of this study was to identify local transmission patterns of Cryptosporidium spp. infections among livestock and humans in four extremely rural and remote highland communities in Madagascar. Methods In this cross-section…
View article: Spatiotemporal variation in risk of<i>Shigella</i>infection in childhood: a global risk mapping and prediction model using individual participant data
Spatiotemporal variation in risk of<i>Shigella</i>infection in childhood: a global risk mapping and prediction model using individual participant data Open
Background Diarrheal disease remains a leading cause of childhood illness and mortality and Shigella is a major etiological contributor for which a vaccine may soon be available. This study aimed to model the spatiotemporal variation in pe…
View article: Prediction of Antibiotic Susceptibility Profiles of Vibrio cholerae Isolates From Whole Genome Illumina and Nanopore Sequencing Data: CholerAegon
Prediction of Antibiotic Susceptibility Profiles of Vibrio cholerae Isolates From Whole Genome Illumina and Nanopore Sequencing Data: CholerAegon Open
During the last decades, antimicrobial resistance (AMR) has become a global public health concern. Nowadays multi-drug resistance is commonly observed in strains of Vibrio cholerae , the etiological agent of cholera. In order to limit the …
View article: Fighting Antimicrobial Resistance: Development and Implementation of the Ghanaian National Action Plan (2017–2021)
Fighting Antimicrobial Resistance: Development and Implementation of the Ghanaian National Action Plan (2017–2021) Open
In recent years, Ghana has been recognised as a leading player in addressing antimicrobial resistance (AMR) in Africa. However, based on our literature review, we could not ascertain whether the core elements of the national action plan (N…
View article: Global Population Genomics of Two Subspecies of <i>Cryptosporidium hominis</i> during 500 Years of Evolution
Global Population Genomics of Two Subspecies of <i>Cryptosporidium hominis</i> during 500 Years of Evolution Open
Cryptosporidiosis is a major global health problem and a primary cause of diarrhea, particularly in young children in low- and middle-income countries (LMICs). The zoonotic Cryptosporidium parvum and anthroponotic Cryptosporidium hominis c…
View article: Characterization of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli From Domestic Free-Range Poultry In Agogo, Ghana
Characterization of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli From Domestic Free-Range Poultry In Agogo, Ghana Open
Background: Extended-spectrum beta-lactamase (ESBLs) producing bacteria in poultry meat has been suggested as one of the sources of resistant genes, that can lead to difficult-to treat infections in humans. This study aims at determining t…
View article: Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis
Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis Open
Bill & Melinda Gates Foundation, Wellcome Trust, and Department of Health and Social Care using UK aid funding managed by the Fleming Fund.
View article: Additional file 1 of Clustering of Cryptosporidium species infections among sheep and cattle but not children in remote highland communities of Madagascar
Additional file 1 of Clustering of Cryptosporidium species infections among sheep and cattle but not children in remote highland communities of Madagascar Open
Additional file 1: Table S1. Study data file.
View article: Associations Between Eight Earth Observation‐Derived Climate Variables and Enteropathogen Infection: An Independent Participant Data Meta‐Analysis of Surveillance Studies With Broad Spectrum Nucleic Acid Diagnostics
Associations Between Eight Earth Observation‐Derived Climate Variables and Enteropathogen Infection: An Independent Participant Data Meta‐Analysis of Surveillance Studies With Broad Spectrum Nucleic Acid Diagnostics Open
Diarrheal disease, still a major cause of childhood illness, is caused by numerous, diverse infectious microorganisms, which are differentially sensitive to environmental conditions. Enteropathogen‐specific impacts of climate remain undere…
View article: Seroprevalence of SARS-CoV-2 in urban settings in three sub-Saharan African countries (SeroCoV): a study protocol for a household-based cross-sectional prevalence study using two-stage cluster sampling
Seroprevalence of SARS-CoV-2 in urban settings in three sub-Saharan African countries (SeroCoV): a study protocol for a household-based cross-sectional prevalence study using two-stage cluster sampling Open
Introduction The current COVID-19 pandemic has impacted the entire world with increasing morbidity and mortality and has resulted in serious economic and social consequences. Assessing the burden of COVID-19 is essential for developing eff…
View article: Global population genomics of two subspecies of<i>Cryptosporidium hominis</i>during 500 years of evolution
Global population genomics of two subspecies of<i>Cryptosporidium hominis</i>during 500 years of evolution Open
Cryptosporidiosis is a major global health problem and a primary cause of diarrhoea, particularly in young children in low- and middle-income countries (LMICs). The zoonotic Cryptosporidium parvum and anthroponotic C. hominis cause most hu…
View article: Prevalence of Pathogens in Young Children Presenting to Hospital with Diarrhea from Lambaréné, Gabon
Prevalence of Pathogens in Young Children Presenting to Hospital with Diarrhea from Lambaréné, Gabon Open
Diarrheal disease is the second most frequent cause of mortality in children younger than 5 years worldwide, causing more than half a million deaths each year. Our knowledge of the epidemiology of potentially pathogenic agents found in chi…
View article: Molecular epidemiology of Respiratory Syncytial Virus in children in sub‐Saharan Africa
Molecular epidemiology of Respiratory Syncytial Virus in children in sub‐Saharan Africa Open
Objectives This study investigated the molecular epidemiology of respiratory syncytial virus (RSV) among febrile children with acute respiratory tract infection in Ghana, Gabon, Tanzania and Burkina Faso between 2014 and 2017 as well as th…
View article: Genetic Diversity of Enteric Viruses in Children under Five Years Old in Gabon
Genetic Diversity of Enteric Viruses in Children under Five Years Old in Gabon Open
Enteric viruses are the leading cause of diarrhea in children globally. Identifying viral agents and understanding their genetic diversity could help to develop effective preventive measures. This study aimed to determine the detection rat…
View article: Molecular and epidemiologic characterization of the diphtheria outbreak in Venezuela
Molecular and epidemiologic characterization of the diphtheria outbreak in Venezuela Open
In 2016, Venezuela faced a large diphtheria outbreak that extended until 2019. Nasopharyngeal or oropharyngeal samples were prospectively collected from 51 suspected cases and retrospective data from 348 clinical records was retrieved from…
View article: Molecular epidemiology of respiratory syncytial virus in children in sub‐Saharan Africa
Molecular epidemiology of respiratory syncytial virus in children in sub‐Saharan Africa Open
Objectives This study investigated the molecular epidemiology of respiratory syncytial virus (RSV) among febrile children with acute respiratory tract infection in Ghana, Gabon, Tanzania and Burkina Faso between 2014 and 2017 as well as th…
View article: Limited specificity of commercially available SARS‐CoV‐2 IgG ELISAs in serum samples of African origin
Limited specificity of commercially available SARS‐CoV‐2 IgG ELISAs in serum samples of African origin Open
Objectives Specific serological tests are mandatory for reliable SARS‐CoV‐2 diagnostics and seroprevalence studies. Here, we assess the specificities of four commercially available SARS‐CoV‐2 IgG ELISAs in serum/plasma panels originating f…