Daniel J. Ericsson
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View article: <scp>AvrSr27</scp> is a zinc‐bound effector with a modular structure important for immune recognition
<span>AvrSr27</span> is a zinc‐bound effector with a modular structure important for immune recognition Open
Summary Effector proteins are central to the success of plant pathogens, while immunity in host plants is driven by receptor‐mediated recognition of these effectors. Understanding the molecular details of effector–receptor interactions is …
View article: The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies
The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies Open
Plant pathogens secrete proteins, known as effectors, that function in the apoplast or inside plant cells to promote virulence. Effector recognition by cell-surface or cytosolic receptors results in the activation of defence pathways and p…
View article: Author Response: The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies
Author Response: The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies Open
Plant pathogens secrete proteins, known as effectors, that function in the apoplast or inside plant cells to promote virulence. Effector recognition by cell-surface or cytosolic receptors results in the activation of defence pathways and p…
View article: The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies
The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies Open
Plant pathogens secrete proteins, known as effectors, that function in the apoplast or inside plant cells to promote virulence. Effector recognition by cell-surface or cytosolic receptors results in the activation of defence pathways and p…
View article: Reviewer #2 (Public Review): The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies
Reviewer #2 (Public Review): The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies Open
Plant pathogens secrete proteins, known as effectors, that function in the apoplast or inside plant cells to promote virulence. Effector recognition by cell-surface or cytosolic receptors results in the activation of defence pathways and p…
View article: Reviewer #1 (Public Review): The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies
Reviewer #1 (Public Review): The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies Open
Plant pathogens secrete proteins, known as effectors, that function in the apoplast or inside plant cells to promote virulence. Effector recognition by cell-surface or cytosolic receptors results in the activation of defence pathways and p…
View article: AvrSr27 is a zinc-bound effector with a modular structure important for immune recognition
AvrSr27 is a zinc-bound effector with a modular structure important for immune recognition Open
Stem rust, caused by the fungal pathogen Puccinia graminis f. sp.tritici ( Pgt ) is a major threat for wheat production and global food security. Central to the success of Pgt is the secretion of proteinaceous effectors that promote infect…
View article: Plant pathogenic fungi hijack phosphate starvation signaling with conserved enzymatic effectors
Plant pathogenic fungi hijack phosphate starvation signaling with conserved enzymatic effectors Open
Phosphate availability modulates plant immune function and regulates interactions with beneficial, phosphate-providing, microbes. Here, we describe the hijacking of plant phosphate sensing by a family of Nudix hydrolase effectors from path…
View article: The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies
The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies Open
Plant pathogens secrete proteins, known as effectors, that function in the apoplast or inside plant cells to promote virulence. Effector recognition by cell-surface or cytosolic receptors results in the activation of defence pathways and p…
View article: The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies
The structural repertoire of Fusarium oxysporum f. sp. lycopersici effectors revealed by experimental and computational studies Open
Plant pathogens secrete proteins, known as effectors, that function in the apoplast or inside plant cells to promote virulence. Effector detection by cell-surface or cytosolic receptors results in the activation of defence pathways and pla…
View article: A rust‐fungus Nudix hydrolase effector decaps <scp>mRNA</scp><i>in vitro</i> and interferes with plant immune pathways
A rust‐fungus Nudix hydrolase effector decaps <span>mRNA</span><i>in vitro</i> and interferes with plant immune pathways Open
Summary To infect plants, pathogenic fungi secrete small proteins called effectors. Here, we describe the catalytic activity and potential virulence function of the Nudix hydrolase effector AvrM14 from the flax rust fungus ( Melampsora lin…
View article: The stem rust effector protein AvrSr50 escapes Sr50 recognition by a substitution in a single surface‐exposed residue
The stem rust effector protein AvrSr50 escapes Sr50 recognition by a substitution in a single surface‐exposed residue Open
Summary Pathogen effectors are crucial players during plant colonisation and infection. Plant resistance mostly relies on effector recognition to activate defence responses. Understanding how effector proteins escape from plant surveillanc…
View article: The structural repertoire of <i>Fusarium oxysporum</i> f. sp. <i>lycopersici</i> effectors revealed by experimental and computational studies
The structural repertoire of <i>Fusarium oxysporum</i> f. sp. <i>lycopersici</i> effectors revealed by experimental and computational studies Open
Plant pathogens secrete proteins, known as effectors, that function in the apoplast or inside plant cells to promote virulence. Effector recognition by cell-surface or cytosolic receptors results in the activation of defence pathways and p…
View article: The crystal structure of SnTox3 from the necrotrophic fungus <i>Parastagonospora nodorum</i> reveals a unique effector fold and provides insight into Snn3 recognition and pro‐domain protease processing of fungal effectors
The crystal structure of SnTox3 from the necrotrophic fungus <i>Parastagonospora nodorum</i> reveals a unique effector fold and provides insight into Snn3 recognition and pro‐domain protease processing of fungal effectors Open
Summary Plant pathogens cause disease through secreted effector proteins, which act to promote infection. Typically, the sequences of effectors provide little functional information and further targeted experimentation is required. Here, w…
View article: CSD 2010348: Experimental Crystal Structure Determination
CSD 2010348: Experimental Crystal Structure Determination Open
An entry from the Inorganic Crystal Structure Database, the world’s repository for inorganic crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely availabl…
View article: Crystal structure of posnjakite formed in the first crystal water-cooling line of the ANSTO Melbourne Australian Synchrotron MX1 Double Crystal Monochromator
Crystal structure of posnjakite formed in the first crystal water-cooling line of the ANSTO Melbourne Australian Synchrotron MX1 Double Crystal Monochromator Open
Exceptionally large crystals of posnjakite, Cu 4 SO 4 (OH) 6 (H 2 O), formed during corrosion of a Swagelock(tm) Snubber copper gasket within the MX1 beamline at the ANSTO-Melbourne, Australian Synchrotron. The crystal structure was solved…
View article: The crystal structure of SnTox3 from the necrotrophic fungus<i>Parastagonospora nodorum</i>reveals a unique effector fold and insights into Kex2 protease processing of fungal effectors
The crystal structure of SnTox3 from the necrotrophic fungus<i>Parastagonospora nodorum</i>reveals a unique effector fold and insights into Kex2 protease processing of fungal effectors Open
Summary Plant pathogens cause disease through secreted effector proteins, which act to modulate host physiology and promote infection. Typically, the sequences of effectors provide little functional information and further targeted experim…
View article: Dead or alive and kicking
Dead or alive and kicking Open
For snart tio ar sedan skrev jag en bok med den nagot pretentiosa titeln “Den ododa musiken: Essaer om teknologi, ledarskap och kreativitet”. Min utgangspunkt var att musikens falt inte langre var ...
View article: NAD <sup>+</sup> cleavage activity by animal and plant TIR domains in cell death pathways
NAD <sup>+</sup> cleavage activity by animal and plant TIR domains in cell death pathways Open
NAD depletion as pathogen response One way that plants respond to pathogen infection is by sacrificing the infected cells. The nucleotide-binding leucine-rich repeat immune receptors responsible for this hypersensitive response carry Toll/…
View article: Structural and functional insights into the modulation of the activity of a flax cytokinin oxidase by flax rust effector AvrL567‐A
Structural and functional insights into the modulation of the activity of a flax cytokinin oxidase by flax rust effector AvrL567‐A Open
Summary During infection, plant pathogens secrete effector proteins to facilitate colonization. In comparison with our knowledge of bacterial effectors, the current understanding of how fungal effectors function is limited. In this study, …
View article: MX2: a high-flux undulator microfocus beamline serving both the chemical and macromolecular crystallography communities at the Australian Synchrotron
MX2: a high-flux undulator microfocus beamline serving both the chemical and macromolecular crystallography communities at the Australian Synchrotron Open
MX2 is an in-vacuum undulator-based crystallography beamline at the 3 GeV Australian Synchrotron. The beamline delivers hard X-rays in the energy range 4.8–21 keV to a focal spot of 22 × 12 µm FWHM (H × V). At 13 keV the flux at the sample…
View article: S4D:5 Targeted next-generation sequencing suggests novel risk loci in juvenile onset systemic lupus erythematosus
S4D:5 Targeted next-generation sequencing suggests novel risk loci in juvenile onset systemic lupus erythematosus Open
Purpose Childhood onset systemic lupus erythematosus (SLE) is associated with a more aggressive disease course and higher mortality risk than adult onset SLE. It has been suggested that juvenile onset SLE cases could have a more geneticall…
View article: CCDC 1859426: Experimental Crystal Structure Determination
CCDC 1859426: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1859425: Experimental Crystal Structure Determination
CCDC 1859425: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1859427: Experimental Crystal Structure Determination
CCDC 1859427: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Crystal structure of the <i>Melampsora lini</i> effector AvrP reveals insights into a possible nuclear function and recognition by the flax disease resistance protein P
Crystal structure of the <i>Melampsora lini</i> effector AvrP reveals insights into a possible nuclear function and recognition by the flax disease resistance protein P Open
Summary The effector protein AvrP is secreted by the flax rust fungal pathogen ( Melampsora lini ) and recognized specifically by the flax ( Linum usitatissimum ) P disease resistance protein, leading to effector‐triggered immunity. To inv…
View article: Structure and Function of the TIR Domain from the Grape NLR Protein RPV1
Structure and Function of the TIR Domain from the Grape NLR Protein RPV1 Open
The N-terminal Toll/interleukin-1 receptor/resistance protein (TIR) domain has been shown to be both necessary and sufficient for defense signaling in the model plants flax and Arabidopsis. In examples from these organisms, TIR domain self…
View article: Structural and Biochemical Analysis of a Single Amino-Acid Mutant of WzzBSF That Alters Lipopolysaccharide O-Antigen Chain Length in Shigella flexneri
Structural and Biochemical Analysis of a Single Amino-Acid Mutant of WzzBSF That Alters Lipopolysaccharide O-Antigen Chain Length in Shigella flexneri Open
Lipopolysaccharide (LPS), a surface polymer of Gram-negative bacteria, helps bacteria survive in different environments and acts as a virulence determinant of host infection. The O-antigen (Oag) component of LPS exhibits a modal chain-leng…