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View article: Photo-induced enhanced Raman spectroscopy as a probe for photocatalytic surfaces
Photo-induced enhanced Raman spectroscopy as a probe for photocatalytic surfaces Open
Photo-induced enhanced Raman spectroscopy (PIERS) has emerged as a highly sensitive surface-enhanced Raman spectroscopy (SERS) technique for the detection of ultra-low concentrations of organic molecules. The PIERS mechanism has been large…
View article: Probing the Role of Atomic Defects in Photocatalytic Systems through Photoinduced Enhanced Raman Scattering
Probing the Role of Atomic Defects in Photocatalytic Systems through Photoinduced Enhanced Raman Scattering Open
Even in ultralow quantities, oxygen vacancies (VO) drastically impact key properties of metal oxide semiconductors, such as charge transport, surface adsorption, and reactivity, playing central roles in functional materials performance. Cu…
View article: A National Assessment of Diagnostic Test Use for Patients with Advanced NSCLC and Factors Influencing Physician Decision-Making.
A National Assessment of Diagnostic Test Use for Patients with Advanced NSCLC and Factors Influencing Physician Decision-Making. Open
BACKGROUND: Diagnostic tests, including US Food and Drug Administration (FDA)-approved tests and laboratory-developed tests, are frequently used to guide care for patients with cancer, and, recently, have been the subject of several policy…
View article: Surface Oxygen Vacancies: Dynamics of Photo‐Induced Surface Oxygen Vacancies in Metal‐Oxide Semiconductors Studied Under Ambient Conditions (Adv. Sci. 22/2019)
Surface Oxygen Vacancies: Dynamics of Photo‐Induced Surface Oxygen Vacancies in Metal‐Oxide Semiconductors Studied Under Ambient Conditions (Adv. Sci. 22/2019) Open
Surface oxygen vacancy defects are some of the most reactive sites but are notoriously difficult to detect, often healing upon exposure to air. In article number https://doi.org/10.1002/advs.201901841, Ivan P. Parkin, Stefan A. Maier, and …
View article: Dynamics of Photo‐Induced Surface Oxygen Vacancies in Metal‐Oxide Semiconductors Studied Under Ambient Conditions
Dynamics of Photo‐Induced Surface Oxygen Vacancies in Metal‐Oxide Semiconductors Studied Under Ambient Conditions Open
Surface‐enhanced Raman spectroscopy (SERS) is a powerful analytical technique commonly used in the detection of traces of organic molecules. The mechanism of SERS is of a dual nature, with Raman scattering enhancements due to a combination…
View article: Applications in catalysis, photochemistry, and photodetection: general discussion
Applications in catalysis, photochemistry, and photodetection: general discussion Open
International audience
View article: Treatment Sequencing in Advanced <i>BRAF</i>-Mutant Melanoma Patients: Current Practice in the United States
Treatment Sequencing in Advanced <i>BRAF</i>-Mutant Melanoma Patients: Current Practice in the United States Open
Background: Treatment of advanced BRAF-mutant melanoma has changed dramatically in the past 3 years thanks to the approval of new immunotherapy and targeted therapy agents. Objectives: The goal of our survey was to investigate when immunot…
View article: Variability in the therapeutic management of advanced ovarian cancer patients: a five-country survey of oncologists
Variability in the therapeutic management of advanced ovarian cancer patients: a five-country survey of oncologists Open
This survey provides real-world data on how advanced ovarian cancer patients are currently treated: 1) BRCA testing was not performed systematically, which raises concerns regarding access to treatment and 2) absence of consensus regarding…
View article: Higher Nevus Count Exhibits a Distinct DNA Methylation Signature in Healthy Human Skin: Implications for Melanoma
Higher Nevus Count Exhibits a Distinct DNA Methylation Signature in Healthy Human Skin: Implications for Melanoma Open
High nevus count is the strongest risk factor for melanoma, and although gene variants have been discovered for both traits, epigenetic variation is unexplored. We investigated 322 healthy human skin DNA methylomes associated with total bo…
View article: Communication practices and awareness of resources for acromegaly patients among endocrinologists
Communication practices and awareness of resources for acromegaly patients among endocrinologists Open
There are unmet needs with respect to increasing awareness among physicians of the importance of patient adherence to therapy, resources available to patients, and how collaboration among patients, nurses, and physicians can improve adhere…
View article: Positive Association Between Vitamin D Serum Levels and Naevus Counts
Positive Association Between Vitamin D Serum Levels and Naevus Counts Open
Lower vitamin D serum levels are linked to increased melanoma risk and poorer survival. Naevus counts are associated with both melanoma risk and survival and to leucocyte telomere length. Vitamin D is also linked to telomere biology with h…
View article: Pregnancy and melanoma: a European‐wide survey to assess current management and a critical literature overview
Pregnancy and melanoma: a European‐wide survey to assess current management and a critical literature overview Open
Background Management of melanoma during pregnancy can be extremely challenging. The reported incidence of melanoma in pregnancy ranges from 2.8 to 5.0 per 100 000 pregnancies. There are no guidelines for the management of melanoma during …
View article: Quantifying the degree of sharing of genetic and non-genetic causes of gene expression variability across four tissues
Quantifying the degree of sharing of genetic and non-genetic causes of gene expression variability across four tissues Open
Gene expression can provide biological mechanisms which underlie genetic associations with complex traits and diseases, but often the most relevant tissue for the trait is inaccessible and a proxy is the only alternative. Here, we investig…
View article: Self-reported physician practices in pulmonary arterial hypertension: Diagnosis, assessment, and referral
Self-reported physician practices in pulmonary arterial hypertension: Diagnosis, assessment, and referral Open
Self-reported clinical practices often deviated from established guidelines. Future research should focus on both clinical efficacy and ways to encourage clinicians to bring their practices in line with well-supported, evidence-based recom…
View article: Genotype score associated with the risk of androgenetic alopecia.
Genotype score associated with the risk of androgenetic alopecia. Open
Abbreviations: OR, odds ratio; CI, confidence interval.a-The top SNPs from each genome-wide significant loci as shown in Table 2 are used in risk score analysis.
View article: Genome-wide meta-analysis results for AGA in MAAN.
Genome-wide meta-analysis results for AGA in MAAN. Open
(A) Manhattan plot showing the −log10 p value of SNPs against their chromosomal positions. The genome-wide significant SNPs are green (p value<5×10−8). The points with p value <1×10−40 were truncated; the smallest p value was 2.4×10−91 at …
View article: Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up
Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up Open
In the International Visible Trait Genetics (VisiGen) Consortium, we investigated the genetics of human skin color by combining a series of genome-wide association studies (GWAS) in a total of 17,262 Europeans with functional follow-up of …
View article: Erratum: Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants
Erratum: Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants Open
Nature Communications 6: Article number: 7211 (2015); Published 29 May 2015; Updated 29 July 2015. The HTML version of this Article incorrectly included all members of The Multiple Tissue Human Expression Resource Consortium in the list of…
View article: Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up
Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up Open
In the International Visible Trait Genetics (VisiGen) Consortium, we investigated the genetics of human skin color by combining a series of genome-wide association studies (GWAS) in a total of 17,262 Europeans with functional follow-up of …
View article: Inhaled Nitric Oxide in Acute Pulmonary Embolism: A Systematic Review
Inhaled Nitric Oxide in Acute Pulmonary Embolism: A Systematic Review Open
Acute pulmonary embolism (PE) is usually a complication secondary to migration of a deep venous clot or thrombi to lungs, but other significant etiologies include air, amniotic fluid, fat, and bone marrow. Regardless of the underlying etio…
View article: High nevus counts confer a favorable prognosis in melanoma patients
High nevus counts confer a favorable prognosis in melanoma patients Open
A high number of nevi is the most significant phenotypic risk factor for melanoma and is in part genetically determined. The number of nevi decreases from middle age onward but this senescence can be delayed in patients with melanoma. We i…
View article: Height and Bone Mineral Density Are Associated with Naevus Count Supporting the Importance of Growth in Melanoma Susceptibility
Height and Bone Mineral Density Are Associated with Naevus Count Supporting the Importance of Growth in Melanoma Susceptibility Open
Naevus count is the strongest risk factor for melanoma. Body Mass Index (BMI) has been linked to melanoma risk. In this study, we investigate the link between naevus count and height, weight and bone mineral density (BMD) in the TwinsUK co…