Daniel Hadfield
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View article: Rapid response teams and recommended ward-based management of acute deterioration: a single-centre retrospective cohort study in an inner-city London (UK) teaching hospital
Rapid response teams and recommended ward-based management of acute deterioration: a single-centre retrospective cohort study in an inner-city London (UK) teaching hospital Open
Objectives To describe the associations between Rapid Response Team (RRT) patient review and other predefined clinical management actions, with risk of in-hospital cardiac arrest and in-hospital mortality in the first unplanned admission (…
View article: Whole blood thiamine, intravenous thiamine supplementation and delirium occurrence in the intensive care unit: retrospective cohort analyses
Whole blood thiamine, intravenous thiamine supplementation and delirium occurrence in the intensive care unit: retrospective cohort analyses Open
View article: Opioid, sedative, preadmission medication and iatrogenic withdrawal risk in UK adult critically ill patients: a point prevalence study
Opioid, sedative, preadmission medication and iatrogenic withdrawal risk in UK adult critically ill patients: a point prevalence study Open
View article: Opioid, sedative, pre-admission medication and iatrogenic withdrawal risk in UK adult critically ill patients: a point prevalence study
Opioid, sedative, pre-admission medication and iatrogenic withdrawal risk in UK adult critically ill patients: a point prevalence study Open
Background : Iatrogenic withdrawal syndrome, after exposure medication known to cause withdrawal is recognised, yet under described in adult intensive care. Aim : Investigate, opioid, sedation and preadmission medication practice in critic…
View article: Heterogeneity of surrogate outcome measures used in critical care studies: A systematic review
Heterogeneity of surrogate outcome measures used in critical care studies: A systematic review Open
Background: The choice of outcome measure is a critical decision in the design of any clinical trial, but many Phase III clinical trials in critical care fail to detect a difference between the interventions being compared. This may be bec…
View article: Parenteral Thiamine (PT) for Prevention and Treatment of Delirium in Critical Illness: A Systematic Review (SR)
Parenteral Thiamine (PT) for Prevention and Treatment of Delirium in Critical Illness: A Systematic Review (SR) Open
Rationale Delirium is common in critical illness and has poor outcomes, including cognitive decline. Impaired glucose metabolism is proposed as the final common pathway. Thiaminedi-phosphate (TDP) is essential in glucose metabolism, TDP de…
View article: Factors affecting the use of neurally adjusted ventilatory assist in the adult critical care unit: a clinician survey
Factors affecting the use of neurally adjusted ventilatory assist in the adult critical care unit: a clinician survey Open
Background Neurally adjusted ventilatory assist (NAVA) involves an intricate interaction between patient, clinician and technology. To improve our understanding of this complex intervention and to inform future trials, this survey aimed to…
View article: Neurally adjusted ventilatory assist versus pressure support ventilation: a randomized controlled feasibility trial performed in patients at risk of prolonged mechanical ventilation
Neurally adjusted ventilatory assist versus pressure support ventilation: a randomized controlled feasibility trial performed in patients at risk of prolonged mechanical ventilation Open
View article: Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial
Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial Open
UK Efficacy and Mechanism Evaluation Programme and National Institutes of Health.
View article: 37th International Symposium on Intensive Care and Emergency Medicine (part 1 of 3)
37th International Symposium on Intensive Care and Emergency Medicine (part 1 of 3) Open
Legend 1: Figure 1 Long-term transgene expression efficiency in mMSCs after lentiviral vector transduction
View article: Epidemiological characteristics, practice of ventilation, and clinical outcome in patients at risk of acute respiratory distress syndrome in intensive care units from 16 countries (PRoVENT): an international, multicentre, prospective study
Epidemiological characteristics, practice of ventilation, and clinical outcome in patients at risk of acute respiratory distress syndrome in intensive care units from 16 countries (PRoVENT): an international, multicentre, prospective study Open