Daniel Körfer
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View article: Impact of sleep apnea treatment on cardiometabolic parameters in a large national multicenter alliance registry
Impact of sleep apnea treatment on cardiometabolic parameters in a large national multicenter alliance registry Open
In this multicenter registry of patients with cardiometabolic disease, PAP use was associated with improvement of cardiometabolic key risk factors. This effect was observed for SBP and DBP even after adjusting for medication adherence.
View article: Case Report: A heterozygous loss-of-function variant of the ERG gene in a family with vascular pathologies
Case Report: A heterozygous loss-of-function variant of the ERG gene in a family with vascular pathologies Open
Background The transcription factor ERG (erythroblast transformation-specific-related gene) has been identified as a key regulator of vascular function by suppressing inflammation in endothelial cells (ECs). Dysregulation of ERG due to gen…
View article: Genetic variants in patients with multiple arterial aneurysms
Genetic variants in patients with multiple arterial aneurysms Open
Purpose The aim of this study was to identify causal genetic variants in patients with multiple arterial aneurysms. Methods From a total cohort of 3107 patients diagnosed with an arterial aneurysm from 2006 to 2016, patients with known her…
View article: Trends and Outcomes of Heart Failure Hospitalizations during COVID-19 Pandemic
Trends and Outcomes of Heart Failure Hospitalizations during COVID-19 Pandemic Open
Background COVID-19 has affected many hospitalizations. In this study, we intended to understand the effects of COVID-19 pandemic on heart failure hospitalizations in the state of California. Method This study was a retrospective analysis …
View article: Histopathological Characterization of Abdominal Aortic Aneurysms from Patients with Multiple Aneurysms Compared to Patients with a Single Abdominal Aortic Aneurysm
Histopathological Characterization of Abdominal Aortic Aneurysms from Patients with Multiple Aneurysms Compared to Patients with a Single Abdominal Aortic Aneurysm Open
The aim of this study was to investigate histopathological differences in abdominal aortic aneurysms (AAAs) between patients with multiple and single arterial aneurysms, as we suspect that there are different underlying mechanisms in aneur…
View article: Multiple Arterial Dissections and Connective Tissue Abnormalities
Multiple Arterial Dissections and Connective Tissue Abnormalities Open
Background: Although patients with multiple arterial dissections in distinct arterial regions rarely present with known connective tissue syndromes, we hypothesized that mild connective tissue abnormalities are common findings in these pat…
View article: Arterial Aneurysm Localization Is Sex-Dependent
Arterial Aneurysm Localization Is Sex-Dependent Open
The aim of this study was to investigate sex-dependent aneurysm distributions. A total of 3107 patients with arterial aneurysms were diagnosed from 2006 to 2016. Patients with anything other than true aneurysms, hereditary connective tissu…
View article: Genetic Variation in LRP1 Associates with Stanford Type B Aortic Dissection Risk and Clinical Outcome
Genetic Variation in LRP1 Associates with Stanford Type B Aortic Dissection Risk and Clinical Outcome Open
Genetic variation in LRP1 (low-density lipoprotein receptor-related protein 1) was reported to be associated with thoracic aortic dissections and aneurysms. The aims of this study were to confirm this association in a prospective single-ce…
View article: Inflammasomes in the Pathophysiology of Aortic Disease
Inflammasomes in the Pathophysiology of Aortic Disease Open
Aortic diseases comprise aneurysms, dissections, and several other pathologies. In general, aging is associated with a slow but progressive dilation of the aorta, along with increased stiffness and pulse pressure. The progression of aortic…
View article: Acute Stanford type B aortic dissection—who benefits from genetic testing?
Acute Stanford type B aortic dissection—who benefits from genetic testing? Open
Selection of patients on the basis of young age and familial inheritance of aortic disease favors the identification of disease-causing genetic variants in a clinical cohort of patients with Stanford type B aortic dissection.