Daniel Lamberty
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The Inhibition Study of Cytochrome bd Oxidase Using the Enzyme-Based Electrochemical Sensor Open
Membrane proteins that participate in multiple vital functions of every living organism such as transport, signaling and respiration, provide 80 to 90% of the relevant targets for the pharmaceutical industries. The family of cytochrome bd …
Cover Feature: Atroposelective Synthesis of Isoriccardin C through a C−H Activated Heck Type Macrocyclization (Eur. J. Org. Chem. 9/2021) Open
The Cover Feature shows a chiral sulfinyl auxiliary in the ortho-position of a biaryl axis inducing a C–H activated atroposelective macrocyclization with final transformation to the configurationally stable natural Isoriccardin C. More inf…
Atroposelective Synthesis of Isoriccardin C through a C−H Activated Heck Type Macrocyclization Open
Macrocyclization is typically the key step in syntheses of cyclophane‐type natural products. Considering compounds with axially chiral biaryl moieties, the control of atroposelectivity is essential for biological activity and is synthetica…