Daniel M. Prevedello
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View article: IMG-45. Impact of Intraoperative Ultrasonography in Endoscopic Endonasal Resection of Sellar and Suprasellar Pathologies
IMG-45. Impact of Intraoperative Ultrasonography in Endoscopic Endonasal Resection of Sellar and Suprasellar Pathologies Open
BACKGROUND AND OBJECTIVES Although most diseases affecting the sella and suprasellar region are benign, critical neurovascular structures contribute to early symptoms and potential for postoperative morbidity. We assessed the role of intra…
View article: AAV9-mediated transduction of memory circuits following convection-enhanced delivery into the olfactory bulbs
AAV9-mediated transduction of memory circuits following convection-enhanced delivery into the olfactory bulbs Open
This study explores the potential of adeno-associated virus serotype 9 (AAV9) to deliver therapeutic genes directly into the memory circuit throughout the olfactory bulb (OB), a critical memory and sensory processing region. Using convecti…
View article: A novel lesion severity index to predict 90-day postoperative survival in brain metastasis patients
A novel lesion severity index to predict 90-day postoperative survival in brain metastasis patients Open
Introduction Brain metastasis patients require granular surgical risk evaluation. The authors aimed to improve prognostication for brain metastasis patients by creating the Metastatic Brain Lesion Score (MBLS). Methods This is a retrospect…
View article: Papillary craniopharyngioma management in the era of BRAF and MEK inhibition
Papillary craniopharyngioma management in the era of BRAF and MEK inhibition Open
Purpose Papillary craniopharyngioma is a rare entity, demonstrating BRAF-V600E mutations in approximately 95% of patients. Recently, a phase 2 trial of patients treated with surgery and BRAF/MEKi demonstrated 91% reduction in residual tumo…
View article: Two-stage surgical strategy for extensive craniofacial fibrous dysplasia with cerebral compression
Two-stage surgical strategy for extensive craniofacial fibrous dysplasia with cerebral compression Open
Background The management of extensive craniofacial fibrous dysplasia requires balancing the extent of resection with the perioperative morbidity and complications. Method The authors describe a case involving the resection of extensive cr…
View article: Use of intraoperative ultrasound in differentiating adamantinomatous versus papillary craniopharyngiomas and guiding resection through the endoscopic endonasal route
Use of intraoperative ultrasound in differentiating adamantinomatous versus papillary craniopharyngiomas and guiding resection through the endoscopic endonasal route Open
View article: Introduction. Advanced techniques for reconstruction following neurosurgical interventions
Introduction. Advanced techniques for reconstruction following neurosurgical interventions Open
View article: Defining the caudal limits of the endoscopic endonasal approach to the craniovertebral junction: anatomic study correlating radiographic measures
Defining the caudal limits of the endoscopic endonasal approach to the craniovertebral junction: anatomic study correlating radiographic measures Open
Objective The endoscopic endonasal approach (EEA), has become the preferred alternative to traditional open and transoral approaches to the ventral craniovertebral junction (CVJ) region. However, preoperative prediction of the limitations …
View article: Practical application of precision oncology in adult onset craniopharyngiomas
Practical application of precision oncology in adult onset craniopharyngiomas Open
Introduction Craniopharyngiomas (CPs) are benign and rare tumors found in adults. Their location close to vital neurovascular structures makes traditional treatment modalities (surgery and radiation) challenging and potentially fraught wit…
View article: Meningioma En Plaque Associated with Cerebrospinal Fluid Rhinorrhea: A Systematic Review of the Literature with Case Presentation
Meningioma En Plaque Associated with Cerebrospinal Fluid Rhinorrhea: A Systematic Review of the Literature with Case Presentation Open
MEP associated with spontaneous CSF rhinorrhea is extremely rare and poses diagnostic and therapeutic challenges. Conservative management for select cases of MEP can be a good choice, sparing the patient from surgical complications, especi…
View article: Short-term Surgical Outcomes of Papillary Craniopharyngiomas: A Multicenter Study
Short-term Surgical Outcomes of Papillary Craniopharyngiomas: A Multicenter Study Open
Purpose: Craniopharyngiomas are rare parasellar tumors, and papillary craniopharyngiomas (PCP) represent 8-20% of cases. We assessed surgical outcomes of these very rare tumors among patients treated in the last decade. Methods: Retrospect…
View article: A Temporary Pause on letters to the editor submissions
A Temporary Pause on letters to the editor submissions Open
View article: Growth dynamics of Rathke's Cleft cyst: a risk score system for surgical decision making
Growth dynamics of Rathke's Cleft cyst: a risk score system for surgical decision making Open
Objective Rathke's cleft cysts (RCCs) exhibit variable growth patterns, thus posing a challenge in predicting progression. While some RCCs may not cause symptoms, others can insidiously cause pituitary dysfunction, which is often irreversi…
View article: The Nasopharyngo‐Septal Butterfly Flap: A Novel Adjunct for Reconstructing Large Skull Base Defects
The Nasopharyngo‐Septal Butterfly Flap: A Novel Adjunct for Reconstructing Large Skull Base Defects Open
Objective Skull base defects can be challenging to reconstruct. The nasoseptal flap (NSF) remains the first‐line option for reconstruction. However, it can be inadequate to cover wide defects or compromised by tumor invasion or prior surge…
View article: Endoscopic endonasal approach for resection of sellar leiomyosarcoma metastasis: illustrative case
Endoscopic endonasal approach for resection of sellar leiomyosarcoma metastasis: illustrative case Open
BACKGROUND Leiomyosarcoma (LMS) is a rare neoplasm that arises from tissues of embryonic mesodermal origin. Primary tissues of origin can include smooth muscle cells of the abdominopelvic viscera, blood vessels, or arrector pili muscles. L…
View article: “Intrasellar tumor-to-tumor metastasis: A single center experience with a systematic review”
“Intrasellar tumor-to-tumor metastasis: A single center experience with a systematic review” Open
View article: Relationships of the vidian nerve and internal carotid artery: MRI and intraoperative surgical evaluation
Relationships of the vidian nerve and internal carotid artery: MRI and intraoperative surgical evaluation Open
MRI evaluation adds useful information in planning the surgical approach to petro-spheno-clival regions, even if the identification of VNA, in these cases, may not be radiologically possible. Surgical experience confirms the importance of …
View article: RADT-02 PRE-OPERATIVE VERSUS POST-OPERATIVE FRACTIONATED STEREOTACTIC RADIOTHERAPY: A SINGLE-INSTITUTION ANALYSIS OF 534 RESECTED METASTASES
RADT-02 PRE-OPERATIVE VERSUS POST-OPERATIVE FRACTIONATED STEREOTACTIC RADIOTHERAPY: A SINGLE-INSTITUTION ANALYSIS OF 534 RESECTED METASTASES Open
Patients with large or symptomatic brain metastases and limited intracranial disease typically have surgery followed by post-operative (post-op) stereotactic radiosurgery (SRS). However, SRS can lead to elevated rates of radiation necrosis…
View article: RADT-03 PRE-OPERATIVE SINGLE FRACTION VERSUS FRACTIONATED STEREOTACTIC RADIOTHERAPY: A SINGLE-INSTITUTION ANALYSIS OF 299 RESECTED METASTASES
RADT-03 PRE-OPERATIVE SINGLE FRACTION VERSUS FRACTIONATED STEREOTACTIC RADIOTHERAPY: A SINGLE-INSTITUTION ANALYSIS OF 299 RESECTED METASTASES Open
The treatment standard for patients with large or symptomatic brain metastases and limited intracranial disease is surgical resection followed by post-operative (post-op) stereotactic radiosurgery (SRS). The multicenter PROPS-BM cohort sho…
View article: Tumor biomechanical stiffness by magnetic resonance elastography predicts surgical outcomes and identifies biomarkers in vestibular schwannoma and meningioma
Tumor biomechanical stiffness by magnetic resonance elastography predicts surgical outcomes and identifies biomarkers in vestibular schwannoma and meningioma Open
Variations in the biomechanical stiffness of brain tumors can not only influence the difficulty of surgical resection but also impact postoperative outcomes. In a prospective, single-blinded study, we utilize pre-operative magnetic resonan…
View article: Neurosurgical Management of Patients with Alpha-Gal Syndrome
Neurosurgical Management of Patients with Alpha-Gal Syndrome Open
Alpha-gal syndrome (AGS) is an immunoglobulin E–mediated hypersensitivity to galatcose-alpha-1,3-galactose (alpha-gal), a carbohydrate compound present in nonprimate mammalian products. Initial exposure to alpha-gal most often occurs throu…
View article: Advantages and caveats of endoscopic to the infratemporal fossa as isolated and combined techniques
Advantages and caveats of endoscopic to the infratemporal fossa as isolated and combined techniques Open
Objective Identify the benefits and caveats of combining minimal access approaches to the infratemporal fossa (ITF), such as the endoscopic transnasal, endoscopic transorbital, endoscopic transoral, and endoscopic sublabial transmaxillary …
View article: Correction to: Customized ventral bony and dural opening in the transplanum/transtuberculum and transclival variants of extended endoscopic endonasal approach to suprasellar craniopharyngiomas: an approach‑based stepwise cadaveric dissection and clinical applicability
Correction to: Customized ventral bony and dural opening in the transplanum/transtuberculum and transclival variants of extended endoscopic endonasal approach to suprasellar craniopharyngiomas: an approach‑based stepwise cadaveric dissection and clinical applicability Open
View article: Endoscopic precaruncular medial transorbital and endonasal multiport approaches to the contralateral skull base: a clinicoanatomical study
Endoscopic precaruncular medial transorbital and endonasal multiport approaches to the contralateral skull base: a clinicoanatomical study Open
OBJECTIVE Minimally invasive endoscopic endonasal multiport approaches create additional visualization angles to treat skull base pathologies. The sublabial contralateral transmaxillary (CTM) approach and superior eyelid lateral transorbit…
View article: Management of recurrent giant hemangiopericytoma: illustrative cases
Management of recurrent giant hemangiopericytoma: illustrative cases Open
BACKGROUND Hemangiopericytoma (HPC) is a rare malignancy accounting for 0.4% of intracranial tumors. HPCs are characterized by local aggressiveness, high rates of recurrence, and a tendency to metastasize to extracranial sites. These featu…
View article: Management of frontoethmoidal osteoma causing pneumocephalus and cerebrospinal fluid leakage with minimally invasive techniques: illustrative cases
Management of frontoethmoidal osteoma causing pneumocephalus and cerebrospinal fluid leakage with minimally invasive techniques: illustrative cases Open
BACKGROUND Osteoid osteoma is a common benign bone tumor frequently seen in the frontoethmoid region. However, involvement of the skull base is rare, with few cases previously reported. OBSERVATIONS The authors report two cases of spontane…
View article: The infundibulochiasmatic angle and the favorability of an endoscopic endonasal approach in type IV craniopharyngioma: illustrative case
The infundibulochiasmatic angle and the favorability of an endoscopic endonasal approach in type IV craniopharyngioma: illustrative case Open
BACKGROUND Lesions located in the floor of the third ventricle are among the most difficult to access in neurosurgery. The neurovascular structures can limit transcranial exposure, whereas tumor extension into the third ventricle can limit…
View article: Endoscopic Endonasal Transpterygoid Translacero-Cavernous Resection of Knosp 4 Functioning Pituitary Macroadenoma
Endoscopic Endonasal Transpterygoid Translacero-Cavernous Resection of Knosp 4 Functioning Pituitary Macroadenoma Open
View article: Matrix metalloproteinase 9: An emerging biomarker for classification of adherent vestibular schwannoma
Matrix metalloproteinase 9: An emerging biomarker for classification of adherent vestibular schwannoma Open
Background The progression of vestibular schwannoma (VS) is intricately linked with interactions between schwannoma cells and the extracellular matrix. Surgical resection of VS is associated with substantial risks as tumors are adherent to…
View article: Fluorescence guidance in skull base surgery: Applications and limitations – A systematic review
Fluorescence guidance in skull base surgery: Applications and limitations – A systematic review Open