Daniel M. Trifiletti
YOU?
Author Swipe
View article: RADT-50. SAFETY AND FEASIBILITY OF YTTRIUM-90 GLASS MICROSPHERE RADIATION THERAPY IN RECURRENT GLIOBLASTOMA: RESULTS FROM THE FIRST 12 PATIENTS TREATED IN THE FRONTIER TRIAL
RADT-50. SAFETY AND FEASIBILITY OF YTTRIUM-90 GLASS MICROSPHERE RADIATION THERAPY IN RECURRENT GLIOBLASTOMA: RESULTS FROM THE FIRST 12 PATIENTS TREATED IN THE FRONTIER TRIAL Open
BACKGROUND Glioblastoma (GBM) is highly aggressive with poor prognosis, especially in recurrent cases where treatments are limited. Intra-arterial (IA) Yttrium-90 (Y90) microsphere therapy, FDA-approved for hepatocellular carcinoma, offers…
View article: P17.35.B SAFETY AND FEASIBILITY OF YTTRIUM-90 GLASS MICROSPHERES IN RECURRENT GLIOBLASTOMA: RESULTS FROM THE FIRST 12 PATIENTS TREATED IN THE FRONTIER TRIAL
P17.35.B SAFETY AND FEASIBILITY OF YTTRIUM-90 GLASS MICROSPHERES IN RECURRENT GLIOBLASTOMA: RESULTS FROM THE FIRST 12 PATIENTS TREATED IN THE FRONTIER TRIAL Open
BACKGROUND Glioblastoma (GBM) is highly aggressive with poor prognosis, especially in recurrent cases where treatments are limited. Intra-arterial (IA) Yttrium-90 (Y90) microsphere therapy, CE-marked for hepatic neoplasia, offers the poten…
View article: Sinonasal Sarcomas Management: An International Consensus Statement
Sinonasal Sarcomas Management: An International Consensus Statement Open
Introduction Sinonasal sarcomas are exceedingly rare entities, constituting less than 7% of head and neck sarcomas. Their complex histology needs specialized treatment, which is often based on multimodal approaches including surgery, radia…
View article: Computed Tomography Simulation for Gamma Knife Radiosurgery: Impact on Target Coverage
Computed Tomography Simulation for Gamma Knife Radiosurgery: Impact on Target Coverage Open
This study evaluated the effectiveness of using a traditional computed tomography (CT) simulation scan in the Leksell Gamma Knife® Icon™ workflow for stereotactic radiosurgery. We compared two workflows, one involving a traditional CT simu…
View article: Factors Associated with Advanced Presentations of Melanoma in the United States from 2004-2015: A National Cancer Database Analysis Cohort Study
Factors Associated with Advanced Presentations of Melanoma in the United States from 2004-2015: A National Cancer Database Analysis Cohort Study Open
Purpose: Significant advances have been made in the diagnosis and treatment of melanoma, but mortality remains high. The primary aim of this study was to identify risk factors associated with advanced presentations of melanoma in the US. M…
View article: Stereotactic radiosurgery and fractionated radiation therapy in the management of pituitary tumors
Stereotactic radiosurgery and fractionated radiation therapy in the management of pituitary tumors Open
Pituitary tumors require a diverse, multidisciplinary approach in their management. Stereotactic radiosurgery (single or hypofractionated) and fractionated radiotherapy are integral parts of the armamentarium. With the introduction of high…
View article: RADT-49. IMPACT OF SHORT COURSE RADIOTHERAPY IN REDUCING LYMPHOPENIA IN PATIENTS WITH GLIOBLASTOMA (SAGA STUDY)
RADT-49. IMPACT OF SHORT COURSE RADIOTHERAPY IN REDUCING LYMPHOPENIA IN PATIENTS WITH GLIOBLASTOMA (SAGA STUDY) Open
INTRODUCTION Lymphopenia attributed to postoperative chemoradiotherapy (CRT) can accelerate tumor recurrence and contribute to poor prognosis in GBM. We hypothesize that short course (1-2 weeks) CRT can mitigate lymphopenia compared to sta…
View article: NCOG-29. HIGHER HYPOTHALAMIC RADIATION DOSE AND FEMALE GENDER ARE RELATED TO HIGHER SELF-REPORTED FATIGUE
NCOG-29. HIGHER HYPOTHALAMIC RADIATION DOSE AND FEMALE GENDER ARE RELATED TO HIGHER SELF-REPORTED FATIGUE Open
BACKGROUND Fatigue is among the most common symptoms managed by patients with cancer. Hypothalamic pituitary axis dysfunction has an established role in a subset of patients with fatigue. Our primary aim was to longitudinally assess the im…
View article: Estimating the risk of brain metastasis for patients newly diagnosed with cancer
Estimating the risk of brain metastasis for patients newly diagnosed with cancer Open
Background Brain metastases (BM) affect clinical management and prognosis but limited resources exist to estimate BM risk in newly diagnosed cancer patients. Additionally, guidelines for brain MRI screening are limited. We aimed to develop…
View article: Carbon Ion Radiotherapy: An Evidence-Based Review and Summary Recommendations of Clinical Outcomes for Skull-Base Chordomas and Chondrosarcomas
Carbon Ion Radiotherapy: An Evidence-Based Review and Summary Recommendations of Clinical Outcomes for Skull-Base Chordomas and Chondrosarcomas Open
Skull-base chordoma and chondrosarcoma are rare radioresistant tumors treated with surgical resection and/or radiotherapy. Because of the established dosimetric and biological benefits of heavy particle therapy, we performed a systematic a…
View article: Phase 1, Dose Escalation, Nonrandomized, Open-Label, Clinical Trial Evaluating the Safety and Preliminary Efficacy of Allogenic Adipose-Derived Mesenchymal Stem Cells for Recurrent Glioblastoma: A Clinical Trial Protocol
Phase 1, Dose Escalation, Nonrandomized, Open-Label, Clinical Trial Evaluating the Safety and Preliminary Efficacy of Allogenic Adipose-Derived Mesenchymal Stem Cells for Recurrent Glioblastoma: A Clinical Trial Protocol Open
BACKGROUND AND OBJECTIVES: Despite standard of care with maximal safe resection and chemoradiation, glioblastoma (GBM) is the most common and aggressive type of primary brain cancer. Surgical resection provides a window of opportunity to l…
View article: The incorporation of cognitive-sparing techniques into prophylactic cranial irradiation in the management of small cell lung cancer
The incorporation of cognitive-sparing techniques into prophylactic cranial irradiation in the management of small cell lung cancer Open
The use of prophylactic cranial irradiation (PCI) remains an important component in the management of small cell lung cancer (SCLC). This is due to the high rates of subclinical brain metastases at the time of diagnosis. Following a respon…
View article: Assessment of bladder filling during prostate cancer radiation therapy with ultrasound and cone-beam CT
Assessment of bladder filling during prostate cancer radiation therapy with ultrasound and cone-beam CT Open
Prostate cancer patients undergoing external beam radiation therapy (EBRT) benefit from a full bladder to decrease bowel and bladder toxicity. Ultrasound may offer a proxy metric for evaluation, sparing CBCT dosing. Patients were prospecti…
View article: Comparison of first-line radiosurgery for small-cell and non-small cell lung cancer brain metastases (CROSS-FIRE)
Comparison of first-line radiosurgery for small-cell and non-small cell lung cancer brain metastases (CROSS-FIRE) Open
Introduction Historical reservations regarding stereotactic radiosurgery (SRS) for small-cell lung cancer (SCLC) brain metastases include concerns for short-interval and diffuse central nervous system (CNS) progression, poor prognoses, and…
View article: Facial Nerve Schwannoma Treatment with Stereotactic Radiosurgery (SRS) versus Resection followed by SRS: Outcomes and a Management Protocol
Facial Nerve Schwannoma Treatment with Stereotactic Radiosurgery (SRS) versus Resection followed by SRS: Outcomes and a Management Protocol Open
Background Stereotactic radiosurgery (SRS) and resection are treatment options for patients with facial nerve schwannomas without mass effect. Objective This article evaluates outcomes of patients treated with SRS versus resection + SRS. M…
View article: A Review of the Role of Stereotactic Radiosurgery and Immunotherapy in the Management of Primary Central Nervous System Tumors
A Review of the Role of Stereotactic Radiosurgery and Immunotherapy in the Management of Primary Central Nervous System Tumors Open
Stereotactic radiosurgery (SRS) and immune checkpoint inhibitors (ICIs) are widely used in the management of brain metastases. These therapies are commonly administered concurrently; as SRS may enhance anti-tumor immunity and responsivenes…
View article: NIMG-17. A DEEP LEARNING MODEL FOR DISCRIMINATING TRUE PROGRESSION FROM PSEUDOPROGRESSION IN GLIOBLASTOMA PATIENTS
NIMG-17. A DEEP LEARNING MODEL FOR DISCRIMINATING TRUE PROGRESSION FROM PSEUDOPROGRESSION IN GLIOBLASTOMA PATIENTS Open
INTRODUCTION Glioblastomas (GBMs) are highly aggressive tumors. A common clinical challenge after standard of care treatment is differentiating tumor progression from treatment-related changes, also known as pseudoprogression (PsP). Usuall…