Daniel Martínez-Ramírez
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View article: EPIDEMIOLOGY OF LEVODOPA-INDUCED DYSKINESIA: PREVALENCE AND ASSOCIATED CLINICAL FACTORS IN LATIN AMERICA
EPIDEMIOLOGY OF LEVODOPA-INDUCED DYSKINESIA: PREVALENCE AND ASSOCIATED CLINICAL FACTORS IN LATIN AMERICA Open
Background Although levodopa remains the gold standard treatment for Parkinson’s disease (PD), its chronic use is associated with levodopa-induced dyskinesia (LID), a motor complication that impacts prognosis, quality of life, and treatmen…
View article: Effects of Diabetes Mellitus on Motor and Non-Motor Symptoms in Parkinson’s Disease: A Cross-Sectional Study
Effects of Diabetes Mellitus on Motor and Non-Motor Symptoms in Parkinson’s Disease: A Cross-Sectional Study Open
Introduction: While there is a growing body of evidence indicating a potential connection between Parkinson’s disease and diabetes mellitus, there is a lack of focus on investigating how diabetes correlates with the severity of both motor …
View article: Genotype-phenotype association study conducted on LARGE-PD reveals novel loci associated with Parkinson’s Disease
Genotype-phenotype association study conducted on LARGE-PD reveals novel loci associated with Parkinson’s Disease Open
Background The Latin American Research Consortium on the Genetics of Parkinson’s Disease (LARGE-PD) is a multicenter collaboration aimed at understanding the genetic architecture of Parkinson’s disease (PD) in this underrepresented populat…
View article: Factors associated with psychotic symptoms in ParkinsonÓ?s disease: a cross-sectional study
Factors associated with psychotic symptoms in ParkinsonÓ?s disease: a cross-sectional study Open
Objective:The study aimed to investigate the relationship between autonomic dysfunction, specifically orthostatic hypotension, and the presence of psychosis in Parkinson's disease (PD) patients.In addition, we aimed to identify other non-m…
View article: Association between dopaminergic-induced complications and life satisfaction in ParkinsonÓ?s disease
Association between dopaminergic-induced complications and life satisfaction in ParkinsonÓ?s disease Open
Objective: The aim of this study was to assess the association between dopaminergic-induced complications and satisfaction with life in patients with Parkinson’s disease. Methods: A cross-sectional study was carried out. Subjects were recr…
View article: COVID-19 and Integrated Multidisciplinary Care Model in Parkinson’s Disease: Literature Review & Future Perspectives
COVID-19 and Integrated Multidisciplinary Care Model in Parkinson’s Disease: Literature Review & Future Perspectives Open
Clinical diversity and multi-systemic manifestations of Parkinson’s disease (PD) necessitate the involvement of several healthcare professionals from different disciplines for optimal care. Clinical guidelines recommend that all persons wi…
View article: Editorial: Managing Parkinson's Disease With a Multidisciplinary Perspective
Editorial: Managing Parkinson's Disease With a Multidisciplinary Perspective Open
EDITORIAL article Front. Neurol., 26 November 2021 | https://doi.org/10.3389/fneur.2021.799017
View article: Mucuna pruriens as adjunct therapy to levodopa in advanced Parkinson's disease
Mucuna pruriens as adjunct therapy to levodopa in advanced Parkinson's disease Open
Background: Parkinson’s disease (PD) is a neurodegenerative disorder whose treatment in advanced stages is often complex and challenging. The treatment goal at this stage is to provide greater clinical stability, with less “off” time and l…
View article: Juvenile Dystonia‐Parkinsonism Due to <scp><i>DNAJC6</i></scp> Mutation
Juvenile Dystonia‐Parkinsonism Due to <span><i>DNAJC6</i></span> Mutation Open
Juvenile parkinsonism is a genetically heterogeneous clinical syndrome that typically presents with other movement disorders, neurological, and imaging abnormalities.1 Most cases are caused by recessively inherited mutations. In this paper…
View article: Commentary: Juvenile Dystonia‐Parkinsonism due to <scp><i>DNAJC6</i></scp> Mutation
Commentary: Juvenile Dystonia‐Parkinsonism due to <span><i>DNAJC6</i></span> Mutation Open
This interesting case report by Garza-Brambila et al1 describes an 11-year-old girl presenting delayed motor development as early as 16 months of age and parkinsonian signs from the age of 8 years, initially responding to dopaminergic ther…
View article: Closed-Loop Deep Brain Stimulation to Treat Medication-Refractory Freezing of Gait in Parkinson’s Disease
Closed-Loop Deep Brain Stimulation to Treat Medication-Refractory Freezing of Gait in Parkinson’s Disease Open
Background : Treating medication-refractory freezing of gait (FoG) in Parkinson’s disease (PD) remains challenging despite several trials reporting improvements in motor symptoms using subthalamic nucleus or globus pallidus internus (GPi) …
View article: Lower Urinary Tract and Gastrointestinal Dysfunction Are Common in Early Parkinson’s Disease
Lower Urinary Tract and Gastrointestinal Dysfunction Are Common in Early Parkinson’s Disease Open
Purpose. Autonomic dysfunction is a common nonmotor feature and early manifestation of Parkinsons disease (PD). Autonomic dysfunction in PD is associated with a worse prognosis. We sought to characterize autonomic dysfunction and identify …
View article: Neurophysiological Correlates of Gait in the Human Basal Ganglia and the PPN Region in Parkinson’s Disease
Neurophysiological Correlates of Gait in the Human Basal Ganglia and the PPN Region in Parkinson’s Disease Open
This study aimed to characterize the neurophysiological correlates of gait in the human pedunculopontine nucleus (PPN) region and the globus pallidus internus (GPi) in Parkinson's disease (PD) cohort. Though much is known about the PPN reg…
View article: Factors associated with cognitive impairment in a Mexican multicenter Parkinson’s disease cohort: a cross-sectional comparative study
Factors associated with cognitive impairment in a Mexican multicenter Parkinson’s disease cohort: a cross-sectional comparative study Open
Introducción: El deterioro cognitivo en Parkinson es común y representa un riesgo para demencia.Identificar los factores asociados ayudará a implementar intervenciones tempranas y estudiar la progresión del deterioro cognitivo.Objetivo: Id…
View article: Review of Hereditary and Acquired Rare Choreas
Review of Hereditary and Acquired Rare Choreas Open
The present review discusses clues to the diagnosis of chorea of various etiologies. Authors propose algorithms to help the clinician in the diagnosis of these rare disorders.
View article: Square Biphasic Pulse Deep Brain Stimulation for Parkinson’s Disease: The BiP-PD Study
Square Biphasic Pulse Deep Brain Stimulation for Parkinson’s Disease: The BiP-PD Study Open
Biphasic pulses were well-tolerated and provided similar benefit to conventional DBS. Further studies should address effectiveness of sqBIP in select PD patients.
View article: Changes in Midline Tremor and Gait Following Deep Brain Stimulation for Essential Tremor
Changes in Midline Tremor and Gait Following Deep Brain Stimulation for Essential Tremor Open
Background: Essential tremor (ET) is a common movement disorder characterized by kinetic and postural tremor in the upper extremities and frequently in the midline. Persons with ET often also exhibit gait ataxia. Previous studies have obse…
View article: <i>CAPN1</i> Variants as Cause of Hereditary Spastic Paraplegia Type 76
<i>CAPN1</i> Variants as Cause of Hereditary Spastic Paraplegia Type 76 Open
Background . Autosomal recessive hereditary spastic paraplegias (HSP) are a rare group of hereditary neurodegenerative disorders characterized by spasticity with or without other symptoms. SPG11 gene is the most common cause of autosomal r…
View article: Changes in Midline Tremor and Gait Following Deep Brain Stimulation for Essential Tremor
Changes in Midline Tremor and Gait Following Deep Brain Stimulation for Essential Tremor Open
Background: Essential tremor (ET) is a common movement disorder characterized by kinetic and postural tremor in the upper extremities and frequently in the midline. Persons with ET often also exhibit gait ataxia. Previous studies have obse…
View article: Athetoid Movements as Initial Manifestation of Primary Sjögren Syndrome
Athetoid Movements as Initial Manifestation of Primary Sjögren Syndrome Open
Background: Primary Sjögren syndrome (pSS) is an autoimmune disorder characterized by exocrine gland and extraglandular symptoms. We present a case report of pSS with an initial presentation of athetoid movements. Case Report: A 74-year-ol…
View article: Bilateral Basal Ganglia Necrosis Secondary to Methamphetamine
Bilateral Basal Ganglia Necrosis Secondary to Methamphetamine Open
Bilateral basal ganglia hyperintensities observed by MRI are caused by systemic or toxic-metabolic disorders. The most common agents include carbon monoxide, cyanide, methanol, manganese, disulfiram, and hydrogen sulfide.1 A 28-year-old fe…
View article: Athetoid Movements as Initial Manifestation of Primary Sjögren Syndrome
Athetoid Movements as Initial Manifestation of Primary Sjögren Syndrome Open
Background: Primary Sjögren syndrome (pSS) is an autoimmune disorder characterized by exocrine gland and extraglandular symptoms. We present a case report of pSS with an initial presentation of athetoid movements. Case Report: A 74-year-ol…