Daniel M. Moreira
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Associations of diarrhea and bovine respiratory disease with growth, feed intake, and mortality during the preweaning period of Holsteins and beef-on-dairy calves Open
Diarrhea and bovine respiratory disease (BRD) are the most common illnesses affecting calves during the preweaning period. This retrospective cohort study aimed to evaluate the associations of diarrhea and BRD with ADG, relative ADG (relAD…
View article: Methylation reprogramming associated with aggressive prostate cancer and ancestral disparities
Methylation reprogramming associated with aggressive prostate cancer and ancestral disparities Open
African men are disproportionately impacted by aggressive prostate cancer (PCa). The key to this disparity is both genetic and environmental factors, alluding to epigenetic modifications. However, African-inclusive prostate tumour DNA meth…
View article: Prostate cancer clinicopathological presentation in South-East Africa during the 2010 decade
Prostate cancer clinicopathological presentation in South-East Africa during the 2010 decade Open
Prostate cancer is the leading cause of cancer-associated death among men across Sub-Saharan Africa, with Southern and East Africa ranking first and fifth globally. However, lack of coordinated national cancer registries has biased data to…
Does insulin resistance predict prostate cancer? Results from the Reduction by Dutasteride of Prostate Cancer (REDUCE) Trial Open
Purpose Prior studies testing the association between insulin resistance (IR) and prostate cancer (PC) risk are inconsistent. We examined the association between Homeostatic Assessment of Insulin Resistance (HOMA‐IR; calculated from fastin…
Health Equity Research Outcomes and Improvement Consortium Prostate Cancer Health Precision Africa1K: Closing the Health Equity Gap Through Rural Community Inclusion Open
Prostate cancer shows significant racial disparity, with men of African ancestry disproportionately impacted. While prostate cancer health disparity studies focus on elucidating the contributing socioeconomic, lifestyle, environmental, bio…
View article: Randomized clinical trial evaluating the effects of administering acidogenic boluses at dry-off on udder health, milk yield, and herd removal
Randomized clinical trial evaluating the effects of administering acidogenic boluses at dry-off on udder health, milk yield, and herd removal Open
Acidogenic boluses can mitigate potential negative effects of high milk yield at dry-off on udder health. This randomized controlled trial aimed to investigate the effect of administering acidogenic boluses at dry-off on dry period intrama…
View article: The Potential of Hydrogeodesy to Address Water-related Problems and Sustainability Challenges
The Potential of Hydrogeodesy to Address Water-related Problems and Sustainability Challenges Open
Increasing climatic and human pressures are changing the world's water resources and hydrological processes at unprecedented rates.These changes require monitoring water resources from ground and space at different temporal and spatial sca…
Perioperative outcomes in male patients undergoing cystectomy, radical colorectal procedure or total pelvic exenteration Open
Men undergoing TPE had greater rates of infections and postoperative complications compared to those undergoing radical cystectomy and LAR/APR. From a clinical standpoint, TPE has high morbidity that could provide opportunity for quality i…
View article: Serum Testosterone and Dihydrotestosterone and Incidence and Progression of Lower Urinary Tract Symptoms: Results From the REDUCE Study
Serum Testosterone and Dihydrotestosterone and Incidence and Progression of Lower Urinary Tract Symptoms: Results From the REDUCE Study Open
In REDUCE, higher serum testosterone and higher serum dihydrotestosterone were not associated with either lower urinary tract symptoms incidence in asymptomatic men or lower urinary tract symptoms progression in symptomatic men. These data…
View article: Impact of genomic testing on urologists' treatment preference in favorable risk prostate cancer: A randomized trial
Impact of genomic testing on urologists' treatment preference in favorable risk prostate cancer: A randomized trial Open
Introduction The Oncotype Dx Genomic Prostate Score (GPS) is a 17‐gene relative expression assay that predicts adverse pathology at prostatectomy. We conducted a novel randomized controlled trial to assess the impact of GPS on urologist's …
Data from Statin Use, Serum Lipids, and Prostate Inflammation in Men with a Negative Prostate Biopsy: Results from the REDUCE Trial Open
Statin use is associated with lower advanced prostate cancer risk. In addition to cholesterol lowering, statins have systemic anti-inflammatory properties. However, their effect on histologic prostate inflammation is not well understood, p…
Data from Smoking Is Associated with Acute and Chronic Prostatic Inflammation: Results from the REDUCE Study Open
Both anti- and proinflammatory effects of cigarette smoking have been described. As prostate inflammation is common, we hypothesized smoking could contribute to prostate inflammation. Thus, we evaluated the association of smoking status wi…
Supplementary Table S1 from Statin Use, Serum Lipids, and Prostate Inflammation in Men with a Negative Prostate Biopsy: Results from the REDUCE Trial Open
Supplementary Table S1. Demographic characteristics of REDUCE participants in the analytic cohort, and in the group excluded due to missing lipid levels.
Supplementary Table S1 from Statin Use, Serum Lipids, and Prostate Inflammation in Men with a Negative Prostate Biopsy: Results from the REDUCE Trial Open
Supplementary Table S1. Demographic characteristics of REDUCE participants in the analytic cohort, and in the group excluded due to missing lipid levels.
Supplemental tables 1-5 from Smoking Is Associated with Acute and Chronic Prostatic Inflammation: Results from the REDUCE Study Open
Supplemental tables 1-5. Supplemental Table 1: Inflammation by smoking status. Supplemental Table 2: Inflammation by treatment arm. Supplemental Table 3: Univariable odds ratios of inflammation by smoking status stratified by treatment arm…
Data from Smoking Is Associated with Acute and Chronic Prostatic Inflammation: Results from the REDUCE Study Open
Both anti- and proinflammatory effects of cigarette smoking have been described. As prostate inflammation is common, we hypothesized smoking could contribute to prostate inflammation. Thus, we evaluated the association of smoking status wi…
Data from Statin Use, Serum Lipids, and Prostate Inflammation in Men with a Negative Prostate Biopsy: Results from the REDUCE Trial Open
Statin use is associated with lower advanced prostate cancer risk. In addition to cholesterol lowering, statins have systemic anti-inflammatory properties. However, their effect on histologic prostate inflammation is not well understood, p…
Supplemental tables 1-5 from Smoking Is Associated with Acute and Chronic Prostatic Inflammation: Results from the REDUCE Study Open
Supplemental tables 1-5. Supplemental Table 1: Inflammation by smoking status. Supplemental Table 2: Inflammation by treatment arm. Supplemental Table 3: Univariable odds ratios of inflammation by smoking status stratified by treatment arm…
Supplementary Tables 1 - 2 from Smoking and Risk of Low- and High-Grade Prostate Cancer: Results from the REDUCE Study Open
Supplementary Table 1: Differences in Baseline Characteristics by Number of On-Study Biopsies Received Among Men with No Cancer on the First On-Study Biopsy. Supplementary Table 2: Association between smoking and prostate cancer risk or di…
Supplementary Tables 1 - 2 from Smoking and Risk of Low- and High-Grade Prostate Cancer: Results from the REDUCE Study Open
Supplementary Table 1: Differences in Baseline Characteristics by Number of On-Study Biopsies Received Among Men with No Cancer on the First On-Study Biopsy. Supplementary Table 2: Association between smoking and prostate cancer risk or di…
Data from Smoking and Risk of Low- and High-Grade Prostate Cancer: Results from the REDUCE Study Open
Purpose: Although the relationship between smoking and prostate cancer risk is inconsistent, some studies show that smoking is associated with prostate cancer mortality. Whether this reflects delayed diagnosis or direct smoking-related eff…
Data from Aspirin, NSAIDs, and Risk of Prostate Cancer: Results from the REDUCE Study Open
Purpose: A recent meta-analysis showed that aspirin was associated with reduced prostate cancer risk. As anti-inflammatory medications lower PSA levels, whether these findings reflect reduced prostate cancer detection or lower prostate can…
Data from Aspirin, NSAIDs, and Risk of Prostate Cancer: Results from the REDUCE Study Open
Purpose: A recent meta-analysis showed that aspirin was associated with reduced prostate cancer risk. As anti-inflammatory medications lower PSA levels, whether these findings reflect reduced prostate cancer detection or lower prostate can…
Supplementary Tables 1-2 from Aspirin, NSAIDs, and Risk of Prostate Cancer: Results from the REDUCE Study Open
Supplementary Tables 1-2. Supplementary Table 1. Association between ASA and NSAID use and prostate cancer risk or disease grade vs. non-use stratified by treatment arm Supplementary Table 2. Association between ASA and/or NSAID use and pr…
Supplementary Tables 1-2 from Aspirin, NSAIDs, and Risk of Prostate Cancer: Results from the REDUCE Study Open
Supplementary Tables 1-2. Supplementary Table 1. Association between ASA and NSAID use and prostate cancer risk or disease grade vs. non-use stratified by treatment arm Supplementary Table 2. Association between ASA and/or NSAID use and pr…
Data from Smoking and Risk of Low- and High-Grade Prostate Cancer: Results from the REDUCE Study Open
Purpose: Although the relationship between smoking and prostate cancer risk is inconsistent, some studies show that smoking is associated with prostate cancer mortality. Whether this reflects delayed diagnosis or direct smoking-related eff…
Motif Mining: Finding and Summarizing Remixed Image Content Open
On the Internet, images are no longer static; they have become dynamic content. Thanks to the availability of smartphones with cameras and easy-to-use editing software, images can be remixed (i.e., redacted, edited, and re-combined with ot…
High serum folate is associated with reduced biochemical recurrence after radical prostatectomy: Results from the SEARCH Database Open
Introduction To analyze the association between serum levels of folate and risk of biochemical recurrence after radical prostatectomy among men from the Shared Equal Access Regional Cancer Hospital (SEARCH) database. Materials and Methods …