Daniel Ngabire
YOU?
Author Swipe
View article: Aspilia africana C. D. Adams inhibits the production of lipopolysaccharide-induced inflammatory mediators in murine macrophage RAW264.7 cells by suppressing the NF-κB and PI3K/Akt pathways
Aspilia africana C. D. Adams inhibits the production of lipopolysaccharide-induced inflammatory mediators in murine macrophage RAW264.7 cells by suppressing the NF-κB and PI3K/Akt pathways Open
Aspilia africana C. D. Adams (A. africana) is used in African folk medicine as a wound healing remedy. In this study, the potential anti-inflammatory effects of A. africana were investigated in lipopolysaccharide (LPS)-stimulated RAW264.7 …
View article: Engineering and Preclinical Evaluation of Western Reserve Oncolytic Vaccinia Virus Expressing A167Y Mutant Herpes Simplex Virus Thymidine Kinase
Engineering and Preclinical Evaluation of Western Reserve Oncolytic Vaccinia Virus Expressing A167Y Mutant Herpes Simplex Virus Thymidine Kinase Open
Viral replication of thymidine kinase deleted (tk−) vaccinia virus (VV) is attenuated in resting normal cells, enabling cancer selectivity, however, replication potency of VV-tk− appears to be diminished in cancer cells. Previously, we fou…
View article: M2 Macrophages Mediate the Resistance of Gastric Adenocarcinoma Cells to 5‐Fluorouracil through the Expression of Integrin <i>β</i> 3, Focal Adhesion Kinase, and Cofilin
M2 Macrophages Mediate the Resistance of Gastric Adenocarcinoma Cells to 5‐Fluorouracil through the Expression of Integrin <i>β</i> 3, Focal Adhesion Kinase, and Cofilin Open
Tumor microenvironment components dictate the growth and progression of various cancers. Tumor‐associated macrophages are the most predominant cells in TME and play a major role in cancer invasiveness. Gastric cancer is one of the most com…
View article: Characterization and in vitro cytotoxicity of phytochemicals from Aspilia africana obtained using green extraction techniques
Characterization and in vitro cytotoxicity of phytochemicals from Aspilia africana obtained using green extraction techniques Open
In this study, we investigated the effect of different extraction techniques for the recovery of bioactive secondary metabolites from Aspilia africana (A. africana). Subcritical water extraction (SWE) at different temperatures (SWE140, SWE…
View article: Anti-Inflammatory Effects of <i>Aster incisus</i> through the Inhibition of NF-<i>κ</i>B, MAPK, and Akt Pathways in LPS-Stimulated RAW 264.7 Macrophages
Anti-Inflammatory Effects of <i>Aster incisus</i> through the Inhibition of NF-<i>κ</i>B, MAPK, and Akt Pathways in LPS-Stimulated RAW 264.7 Macrophages Open
Aster incisus is a common flower found in almost all regions of South Korea. In the current study, we investigated the potential antioxidant and anti-inflammatory properties of the Aster incisus methanol extract in LPS-stimulated RAW 264.7…
View article: Induction of apoptosis and G1 phase cell cycle arrest by Aster�incises in AGS gastric adenocarcinoma cells
Induction of apoptosis and G1 phase cell cycle arrest by Aster�incises in AGS gastric adenocarcinoma cells Open
In recent decades, various bioactive compounds from plants have been investigated for their potential use in the treatment of diseases in humans. Aster incisus extract (AIE) is the extract of a common plant that is mostly found in Asia. It…
View article: Autophagy and Inflammatory Response in the Tumor Microenvironment
Autophagy and Inflammatory Response in the Tumor Microenvironment Open
Cell death is the last fate of the life cycle of cells. Different pathways involved in cell death are known to date, and are mostly represented by apoptosis, necrosis, and autophagy. Autophagy is one of the most preserved cell death pathwa…
View article: Anticancer activity of <i>Sasa borealis</i> leaf extract-mediated gold nanoparticles
Anticancer activity of <i>Sasa borealis</i> leaf extract-mediated gold nanoparticles Open
Advancements in metal nanoparticle synthesis using plant extracts and their anticancer activity have received significant attention in recent years. The green approach for the synthesis of gold nanoparticles (AuNPs) using leaf extract of S…