Daniel Pereda
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View article: Mitral Annular Disjunction: A Roadmap for the Surgeon
Mitral Annular Disjunction: A Roadmap for the Surgeon Open
Objectives Mitral annular disjunction (MAD) is a structural abnormality of the mitral annulus fibrosus, associated with myxomatous leaflet degeneration, mitral valve prolapse (MVP), and ventricular arrhythmias. The combination of annular d…
View article: Role of Extracellular Vesicles in Chronic Post-Embolic Pulmonary Hypertension: Data from an Experimental Animal Model and Patients
Role of Extracellular Vesicles in Chronic Post-Embolic Pulmonary Hypertension: Data from an Experimental Animal Model and Patients Open
Background: The pathogenesis of chronic thromboembolic pulmonary hypertension (CTEPH) involves a multifaceted interplay of factors, including incomplete thrombus resolution, endothelial dysfunction, and vascular remodeling. Recent studies …
View article: Establishing a robotic aortic valve replacement program in Spain: growing opportunities for Europe
Establishing a robotic aortic valve replacement program in Spain: growing opportunities for Europe Open
Our initial experience shows that expanding a robotic program to include RAVR is feasible, safe, and can provide excellent clinical outcomes in selected patients.
View article: Dolutegravir-based Antiretroviral Therapy in People With HIV With Solid Organ Transplantation: A Single-arm Pilot Clinical Trial (DTG-SOT)
Dolutegravir-based Antiretroviral Therapy in People With HIV With Solid Organ Transplantation: A Single-arm Pilot Clinical Trial (DTG-SOT) Open
Background This study assessed the pharmacokinetic interactions between dolutegravir (DTG)-based antiretroviral therapy (ART) and immunosuppressants in solid organ transplantation (SOT) recipients with HIV and ART safety. Methods A phase I…
View article: Oral vs. Outpatient Parenteral Antimicrobial Treatment for Infective Endocarditis: Study Protocol for the Spanish OraPAT-IE GAMES Trial
Oral vs. Outpatient Parenteral Antimicrobial Treatment for Infective Endocarditis: Study Protocol for the Spanish OraPAT-IE GAMES Trial Open
gov identifier: NCT05398679.
View article: Examining the learning curves in robotic cardiac surgery wet lab simulation training
Examining the learning curves in robotic cardiac surgery wet lab simulation training Open
BACKGROUND Simulation-based training has gained distinction in cardiothoracic surgery as robotic-assisted cardiac procedures evolve. Despite the increasing use of wet lab simulators, the effectiveness of these training methods and skill ac…
View article: Learning curve of robotic mitral repair: prospective two-centre study of proficiency and clinical outcomes
Learning curve of robotic mitral repair: prospective two-centre study of proficiency and clinical outcomes Open
OBJECTIVES Robotic-assisted mitral valve repair surgery has a steep learning curve, and it is not clear whether previous experience in minimally invasive mitral valve surgery (MIMVS) facilitates this process. We aimed to investigate the in…
View article: CILP1 and NTproBNP in pulmonary hypertension and right ventricular pressure overload: a translational experimental study
CILP1 and NTproBNP in pulmonary hypertension and right ventricular pressure overload: a translational experimental study Open
Introduction Cartilage intermediate layer protein 1 (CILP1) has emerged as a novel marker of right ventricular (RV) dysfunction in pulmonary hypertension (PH), although there is still little evidence on its role in different scenarios of R…
View article: European Association of Cardiothoracic Surgeons future view on robotic cardiac surgery in Europe
European Association of Cardiothoracic Surgeons future view on robotic cardiac surgery in Europe Open
status: Published
View article: Volume-pressure loop hemodynamic characterization of pulmonary hypertension
Volume-pressure loop hemodynamic characterization of pulmonary hypertension Open
Background Pulmonary hypertension (PH) includes a wide spectrum of pathologies with different pathological bases and a variety of clinical scenarios in which right ventricular (RV)-pulmonary artery (PA) coupling has relevant prognostic imp…
View article: Left atrial strain differences between hypertensive and sarcomeric left ventricular hypertrophy: a sign of sarcomeric auricular myopathy?
Left atrial strain differences between hypertensive and sarcomeric left ventricular hypertrophy: a sign of sarcomeric auricular myopathy? Open
Introduction In clinical practice, left ventricular (LV) hypertrophy is a common finding that can be caused by physiologic or pathologic conditions. An etiologic diagnosis is extremely important because it may change the prognosis and mana…
View article: Mitral valve repair with resection and non-resection techniques in Barlow's disease: A multi-center study
Mitral valve repair with resection and non-resection techniques in Barlow's disease: A multi-center study Open
At mid-term, the clinical and echocardiographic results of valve repair for Barlow's disease were very good and MV reintervention was rarely needed. At this time point, the results of non-resection techniques were comparable to the "gold s…
View article: EValuating the Effect of periopeRaTIve empaGliflOzin on cardiac surgery associated acute kidney injury: rationale and design of the VERTIGO study
EValuating the Effect of periopeRaTIve empaGliflOzin on cardiac surgery associated acute kidney injury: rationale and design of the VERTIGO study Open
Background Cardiac surgery-associated acute kidney injury (CSA-AKI) is a serious complication in patients undergoing cardiac surgery with extracorporeal circulation (ECC) that increases postoperative complications and mortality. CSA-AKI de…
View article: Five-year results from a prospective, single-arm European trial on decellularized allografts for aortic valve replacement—the ARISE Study and ARISE Registry Data
Five-year results from a prospective, single-arm European trial on decellularized allografts for aortic valve replacement—the ARISE Study and ARISE Registry Data Open
OBJECTIVES Decellularized aortic homografts (DAH) were introduced as a new option for aortic valve replacement for young patients. METHODS A prospective, EU-funded, single-arm, multicentre study in 8 centres evaluating non-cryopreserved DA…
View article: Minimally Invasive Mitral Valve Repair: From Total Endoscopic To Closed-Chest Robotic
Minimally Invasive Mitral Valve Repair: From Total Endoscopic To Closed-Chest Robotic Open
Minimally invasive cardiac surgery has evolved over the past few decades, thanks to advancements in technology and surgical techniques. These advancements have allowed surgeons to perform cardiac interventions through small incisions, redu…
View article: Closed-chest robotic repair of mitral prolapse. Surgical technique and early results
Closed-chest robotic repair of mitral prolapse. Surgical technique and early results Open
Background Robotic mitral repair is generally performed with four intercostal trocars and a minithoracotomy. We describe our technique and results with a totally-thoracoscopic closed chest approach using a 12 mm valveless trocar as “workin…
View article: The impact of annuloplasty ring or band implantation on post-repair mitral valve haemodynamic performance
The impact of annuloplasty ring or band implantation on post-repair mitral valve haemodynamic performance Open
OBJECTIVES The clinical importance of optimal post-repair mitral valve diastolic performance is increasingly being recognized. The haemodynamic effect of a partial annuloplasty band implantation, in comparison to a full ring, remains insuf…
View article: Repair of mitral prolapse: comparison of thoracoscopic minimally invasive and conventional approaches
Repair of mitral prolapse: comparison of thoracoscopic minimally invasive and conventional approaches Open
OBJECTIVES Surgical repair remains the best treatment for severe primary mitral regurgitation (MR). Minimally invasive mitral valve surgery is being increasingly performed, but there is a lack of solid evidence comparing thoracoscopic with…
View article: Does Quality of Life in Survivors of Surgery for Acute Left-Sided Infective Endocarditis Differ from Non-Endocarditis Patients?
Does Quality of Life in Survivors of Surgery for Acute Left-Sided Infective Endocarditis Differ from Non-Endocarditis Patients? Open
Surgery for left-sided infective endocarditis (IE) has been demonstrated to improve patients’ survival rates but information about quality of life (QoL) after surgery is scarce. The aim of this study was to assess the postoperative outcome…
View article: β3 Adrenergic Agonist Treatment in Chronic Pulmonary Hypertension Associated with Heart Failure (SPHERE-HF): A Double Blind, Placebo-Controlled, Randomized Clinical Trial
β3 Adrenergic Agonist Treatment in Chronic Pulmonary Hypertension Associated with Heart Failure (SPHERE-HF): A Double Blind, Placebo-Controlled, Randomized Clinical Trial Open
Aims Pulmonary hypertension (PH) associated with left heart disease is an increasingly prevalent problem, orphan of targeted therapies, and related to a poor prognosis, particularly when pre- and post-capillary PH combine. The current stud…
View article: Current state of the art and recommendations in robotic mitral valve surgery
Current state of the art and recommendations in robotic mitral valve surgery Open
status: Published