Daniel S. Pine
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View article: Differential developmental influences on anxiety in adulthood: Behavioral inhibition moderates the dimensions of social involvement predicting anxiety in adulthood
Differential developmental influences on anxiety in adulthood: Behavioral inhibition moderates the dimensions of social involvement predicting anxiety in adulthood Open
View article: White matter microstructure alterations in social anxiety disorder – a mega-analysis across 12 cohorts in the ENIGMA-Anxiety Working Group
White matter microstructure alterations in social anxiety disorder – a mega-analysis across 12 cohorts in the ENIGMA-Anxiety Working Group Open
View article: Assessing Behavioral Threat Avoidance in Pediatric Anxiety With Naturalistic Games
Assessing Behavioral Threat Avoidance in Pediatric Anxiety With Naturalistic Games Open
Behavioral avoidance exacerbates anxiety symptoms. Capturing and identifying maladaptive avoidance patterns holds clinical utility. However, effective assessment tools which provide unique information on behavior beyond self‐report are nee…
View article: Integrating Multimodal Neuroimaging of Error Monitoring to Estimate Future Anxiety in Adolescents
Integrating Multimodal Neuroimaging of Error Monitoring to Estimate Future Anxiety in Adolescents Open
Importance Anxiety disorders are highly prevalent and associated with heightened error monitoring, the detection of one’s mistakes. However, error monitoring, anxiety, and their associations change throughout adolescence, limiting the abil…
View article: Correction: Temporal Predictions from Anhedonia To Anxiety in Adolescents with Major Depressive Disorder
Correction: Temporal Predictions from Anhedonia To Anxiety in Adolescents with Major Depressive Disorder Open
View article: Automated classification of exposure and encourage events in speech data from pediatric OCD treatment
Automated classification of exposure and encourage events in speech data from pediatric OCD treatment Open
Objective To develop and evaluate an automated classification system for labeling Exposure Process Coding System (EPCS) quality codes—specifically exposure and encourage events—during in-person exposure therapy sessions using automatic spe…
View article: Sensitivity and Bias in Face-Emotion Labeling: Replication and Extension to Youth With Irritability and Anxiety
Sensitivity and Bias in Face-Emotion Labeling: Replication and Extension to Youth With Irritability and Anxiety Open
View article: Temporal Predictions from Anhedonia To Anxiety in Adolescents with Major Depressive Disorder
Temporal Predictions from Anhedonia To Anxiety in Adolescents with Major Depressive Disorder Open
Anhedonia is a hallmark symptom of major depressive disorder (MDD) characterized by diminished ability to experience pleasure, motivation, or interest in usual activities. Anhedonia also is recognized as a transdiagnostic symptom dimension…
View article: Neural correlates of human fear conditioning and sources of variability in 2199 individuals
Neural correlates of human fear conditioning and sources of variability in 2199 individuals Open
View article: Gamified Attention Bias Modification Training to Augment Cognitive–Behavioral Therapy for Youth Anxiety Disorders: A Randomized Controlled Trial
Gamified Attention Bias Modification Training to Augment Cognitive–Behavioral Therapy for Youth Anxiety Disorders: A Randomized Controlled Trial Open
View article: Identifying neurodevelopmental signatures of worry: An ultra-high field (7-Tesla) fMRI study among adolescents and young adults
Identifying neurodevelopmental signatures of worry: An ultra-high field (7-Tesla) fMRI study among adolescents and young adults Open
Objective: Worry plays an important role in anxiety disorders, but its neurodevelopment remains unclear. Worry increases during adolescence when cognitive-affective neural circuits are developing, impacting girls especially. Activity of an…
View article: Pediatric Anxiety and Movie-Evoked Brain-Heart Communication
Pediatric Anxiety and Movie-Evoked Brain-Heart Communication Open
Anxiety states and symptoms can drive increases in heart rate through alteration in amygdala-prefrontal functioning. How such brain-heart communication mechanisms emerge across development and in naturalistic settings is unclear. In a pedi…
View article: Neural correlates of human fear conditioning and sources of variability in 2199 individuals
Neural correlates of human fear conditioning and sources of variability in 2199 individuals Open
Pavlovian fear conditioning is a fundamental process in both health and disease. We investigated its neural correlates and sources of variability using harmonized functional magnetic resonance imaging data from 2,199 individuals across nin…
View article: Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-Analysis
Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-Analysis Open
View article: Leveraging technology to probe mechanisms of psychopathology: A proof of concept study of inhibitory control
Leveraging technology to probe mechanisms of psychopathology: A proof of concept study of inhibitory control Open
Objective Quantifying relevant behavioral mechanisms has relied on rigorous, time-consuming tools restricted to laboratory settings and inaccessible to the clinical community. Advances in technology provide an opportunity to develop more a…
View article: Study Preregistration: Data-Driven Profiles of Youth Executive Function and Their Longitudinal Associations With Externalizing Problems
Study Preregistration: Data-Driven Profiles of Youth Executive Function and Their Longitudinal Associations With Externalizing Problems Open
View article: Adolescent cognitive control processing is associated with anxiety in young adulthood during the COVID-19 pandemic
Adolescent cognitive control processing is associated with anxiety in young adulthood during the COVID-19 pandemic Open
View article: The roles of parental verbal communication and child characteristics in the transmission and maintenance of social fears
The roles of parental verbal communication and child characteristics in the transmission and maintenance of social fears Open
Background Although social anxiety runs in families, little is known about how parents and children contribute to the intergenerational transmission of social fears. We examined whether mothers transfer social fear beliefs to their childre…
View article: Single-session intervention with and without video support to prevent the worsening of emotional distress among healthcare workers during the SARS-CoV-2 pandemic: a randomised clinical trial
Single-session intervention with and without video support to prevent the worsening of emotional distress among healthcare workers during the SARS-CoV-2 pandemic: a randomised clinical trial Open
Background The SARS-CoV-2 pandemic was a major stressful event that significantly affected healthcare providers. Objective To evaluate the efficacy of a single-session intervention (SSI), with and without weekly personalised prerecorded vi…
View article: Detecting Cry in Daylong Audio Recordings using Machine Learning: The Development and Evaluation of Binary Classifiers
Detecting Cry in Daylong Audio Recordings using Machine Learning: The Development and Evaluation of Binary Classifiers Open
Cry signals distress in infants/children and may serve as an early, ecologically valid, and scalable indicator of irritability, a transdiagnostic mental health risk marker. Machine learning may allow researchers to identify cry (among othe…
View article: Subjective affective experience under threat is shaped by environmental affordances
Subjective affective experience under threat is shaped by environmental affordances Open
In this pre-registered study, we ask how people’s emotional responses under threat may be causally affected by what is available to them in the environment, i.e. environmental affordances. For this purpose, we introduce a novel behavioral …
View article: Introducing the “IJMPR Didactic Papers”
Introducing the “IJMPR Didactic Papers” Open
View article: Structure-function coupling in network connectivity and associations with negative affectivity in a group of transdiagnostic adolescents
Structure-function coupling in network connectivity and associations with negative affectivity in a group of transdiagnostic adolescents Open
View article: From deconstruction to reconstruction: A search for natural kinds in developmental psychopathology.
From deconstruction to reconstruction: A search for natural kinds in developmental psychopathology. Open
A "natural kind" is a specific classification that identifies some structure of truth and reality, a delimited entity. Psychiatric disorders are not natural kinds. As one moves from physics and chemistry to biology and medicine, natural ki…
View article: Extending insights from LeDoux: using movies to study subjective, clinically meaningful experiences in neuroscience
Extending insights from LeDoux: using movies to study subjective, clinically meaningful experiences in neuroscience Open
Neuroscience research with public health relevance to emotional disorders examines brain–behavior relations. Joe LeDoux’s legacy advances these efforts in ways that remain truly unique. While recognized for his basic science research, he a…
View article: Using mobile eye-tracking to evaluate gaze behavior during a speech in pediatric anxiety disorders
Using mobile eye-tracking to evaluate gaze behavior during a speech in pediatric anxiety disorders Open
These findings highlight anxiety-related differences in gaze behavior in youth, providing new mechanistic insight into pediatric anxiety using mobile eye-tracking.
View article: Altered associations between white matter structure and psychopathology in previously institutionalized adolescents
Altered associations between white matter structure and psychopathology in previously institutionalized adolescents Open
View article: Cortical structure and subcortical volumes in conduct disorder: a coordinated analysis of 15 international cohorts from the ENIGMA-Antisocial Behavior Working Group
Cortical structure and subcortical volumes in conduct disorder: a coordinated analysis of 15 international cohorts from the ENIGMA-Antisocial Behavior Working Group Open
Academy of Medical Sciences and Economic and Social Research Council.
View article: Eye-tracking measurement of attention bias to social threat among youth: A replication and extension study
Eye-tracking measurement of attention bias to social threat among youth: A replication and extension study Open
Attentional bias to social threat cues has been linked to heightened anxiety and irritability in youth. Yet, inconsistent methodology has limited replication and led to mixed findings. The current study aims to 1) replicate and extend two …
View article: Associations Between Neighborhood Resources and Youths’ Response to Reward Omission in a Task Modeling Negatively Biased Environments
Associations Between Neighborhood Resources and Youths’ Response to Reward Omission in a Task Modeling Negatively Biased Environments Open
One or more of the authors of this paper self-identifies as a member of one or more historically underrepresented racial and/or ethnic groups in science. One or more of the authors of this paper self-identifies as a member of one or more h…