Daniel Polan
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View article: PET/CT-Based Absorbed Dose Maps in<sup>90</sup>Y Selective Internal Radiation Therapy Correlate with Spatial Changes in Liver Function Derived from Dynamic MRI
PET/CT-Based Absorbed Dose Maps in<sup>90</sup>Y Selective Internal Radiation Therapy Correlate with Spatial Changes in Liver Function Derived from Dynamic MRI Open
Functional liver parenchyma can be damaged from treatment of liver malignancies with 90Y selective internal radiation therapy (SIRT). Evaluating functional parenchymal changes and developing an absorbed dose (AD)-toxicity model can assist …
View article: Stereotactic body radiation therapy (SBRT) following Yttrium-90 (<sup>90</sup>Y) selective internal radiation therapy (SIRT): a feasibility planning study using <sup>90</sup>Y delivered dose
Stereotactic body radiation therapy (SBRT) following Yttrium-90 (<sup>90</sup>Y) selective internal radiation therapy (SIRT): a feasibility planning study using <sup>90</sup>Y delivered dose Open
Objective . 90 Y selective internal radiation therapy (SIRT) treatment of hepatocellular carcinoma (HCC) can potentially underdose lesions, as identified on post-therapy PET/CT imaging. This study introduces a methodology and explores the …
View article: Direct incorporation of patient‐specific efficacy and toxicity estimates in radiation therapy plan optimization
Direct incorporation of patient‐specific efficacy and toxicity estimates in radiation therapy plan optimization Open
Purpose Current radiation therapy (RT) treatment planning relies mainly on pre‐defined dose‐based objectives and constraints to develop plans that aim to control disease while limiting damage to normal tissues during treatment. These objec…
View article: Feasibility of function‐guided lung treatment planning with parametric response mapping
Feasibility of function‐guided lung treatment planning with parametric response mapping Open
Purpose Recent advancements in functional lung imaging have been developed to improve clinicians’ knowledge of patient pulmonary condition prior to treatment. Ultimately, it may be possible to employ these functional imaging modalities to …
View article: Approaches for Incorporating Patient-Specific Response in Radiation Therapy
Approaches for Incorporating Patient-Specific Response in Radiation Therapy Open
In an era of increasingly personalized medical care, radiation therapy (RT) continues to be a prominent and effective focal cancer treatment. However, the standard RT treatment process remains largely uniform, using a one-size-fits-all app…
View article: Biomechanical modeling of radiation dose-induced volumetric changes of the parotid glands for deformable image registration
Biomechanical modeling of radiation dose-induced volumetric changes of the parotid glands for deformable image registration Open
Differences between Morfeus-spatial and Morfeus-spatialDose may be impactful when considering high-dose gradients of radiation in the PGs. The proposed DIR model can allow more accurate PG alignment than the standard model and improve dose…
View article: DIPG-23. BRAINSTEM RADIATION EXPOSURE CONFERS SUBSTANTIAL RISK OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) IN MEDULLOBLASTOMA SURVIVORS: A REPORT FROM THE INTERNATIONAL DIPG REGISTRY
DIPG-23. BRAINSTEM RADIATION EXPOSURE CONFERS SUBSTANTIAL RISK OF DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) IN MEDULLOBLASTOMA SURVIVORS: A REPORT FROM THE INTERNATIONAL DIPG REGISTRY Open
With improved survivorship in medulloblastoma, there has been increasing recognition of the occurrence of secondary malignant brain tumors. To date, no studies have specifically addressed the risk of diffuse intrinsic pontine glioma (DIPG)…
View article: RTHP-19. DIFFUSE INTRINSIC PONTINE GLIOMA AS A LATE COMPLICATION OF MEDULLOBLASTOMA THERAPY
RTHP-19. DIFFUSE INTRINSIC PONTINE GLIOMA AS A LATE COMPLICATION OF MEDULLOBLASTOMA THERAPY Open
Radiation therapy has been associated with increased risk of secondary gliomas in survivors of childhood medulloblastoma. Despite this clear association, no studies have specifically addressed the risk of diffuse intrinsic pontine glioma (…
View article: PDCT-06. DIFFUSE INTRINSIC PONTINE GLIOMA AS A SECONDARY MALIGNANCY: A REPORT FROM THE DIPG REGISTRY AND REVIEW OF THE LITERATURE
PDCT-06. DIFFUSE INTRINSIC PONTINE GLIOMA AS A SECONDARY MALIGNANCY: A REPORT FROM THE DIPG REGISTRY AND REVIEW OF THE LITERATURE Open
Exposure to cranial radiation in childhood increases the risk of subsequent CNS malignancies, an important cause of late mortality. Studies have shown a linear relationship between radiation dose and risk of secondary meningiomas and gliom…
View article: Tissue segmentation of computed tomography images using a Random Forest algorithm: a feasibility study
Tissue segmentation of computed tomography images using a Random Forest algorithm: a feasibility study Open
There is a need for robust, fully automated whole body organ segmentation for diagnostic CT. This study investigates and optimizes a Random Forest algorithm for automated organ segmentation; explores the limitations of a Random Forest algo…