Daniel Q. Huang
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View article: The Effect of Corporate Governance on the Firm’s Cost of Capital: Evidence from the Taiwan Corporate Governance Evaluation System
The Effect of Corporate Governance on the Firm’s Cost of Capital: Evidence from the Taiwan Corporate Governance Evaluation System Open
This study investigates how corporate governance and changes in governance rankings influence firms’ cost of capital. Using data from 1723 Taiwanese listed firms, comprising 11,940 firm-year observations between 2017 and 2024, the analysis…
View article: What Is Your Agent's GPA? A Framework for Evaluating Agent Goal-Plan-Action Alignment
What Is Your Agent's GPA? A Framework for Evaluating Agent Goal-Plan-Action Alignment Open
We introduce the Agent GPA (Goal-Plan-Action) framework: an evaluation paradigm based on an agent's operational loop of setting goals, devising plans, and executing actions. The framework includes five evaluation metrics: Goal Fulfillment,…
View article: Rising burden of steatotic liver disease in women of childbearing age and projections till 2035
Rising burden of steatotic liver disease in women of childbearing age and projections till 2035 Open
View article: In-Hand Manipulation of Articulated Tools with Dexterous Robot Hands with Sim-to-Real Transfer
In-Hand Manipulation of Articulated Tools with Dexterous Robot Hands with Sim-to-Real Transfer Open
Reinforcement learning (RL) and sim-to-real transfer have advanced robotic manipulation of rigid objects. Yet, policies remain brittle when applied to articulated mechanisms due to contact-rich dynamics and under-modeled joint phenomena su…
View article: Aerobic Exercise Training Leads to MASH Resolution as Defined by the MASH Resolution Index
Aerobic Exercise Training Leads to MASH Resolution as Defined by the MASH Resolution Index Open
Purpose Exercise training is recommended for all patients with metabolic dysfunction-associated steatotic liver disease. Whether exercise training improves liver histology independent of body weight loss remains controversial. Given the in…
View article: Quantification of liver steatosis of metabolic dysfunction-associated steatotic liver disease based on body composition analysis
Quantification of liver steatosis of metabolic dysfunction-associated steatotic liver disease based on body composition analysis Open
View article: Contemporary Changes in Global Trends in Early-Onset Cancer: Incidence and Mortality (2000–2021)
Contemporary Changes in Global Trends in Early-Onset Cancer: Incidence and Mortality (2000–2021) Open
Background/Objectives: The burden of early-onset cancer (cancer incidence <50 years) has increased globally. Early-onset cancer carries significant societal and economic consequences. We aim to provide updated estimates for incidence and m…
View article: Comparative analysis of patient-derived organoids and patient-derived xenografts as avatar models for predicting response to anti-cancer therapy
Comparative analysis of patient-derived organoids and patient-derived xenografts as avatar models for predicting response to anti-cancer therapy Open
Patient-derived xenografts (PDX) and organoids (PDO) are widely used to model cancer and predict treatment response in matched patients. However, their predictive accuracy has not been systematically studied nor compared. We conducted a sy…
View article: Impact of metabolic dysfunction on treatment responses to nucleos(t)ide analogues in chronic hepatitis B: a retrospective multi-center REAL-B cohort study
Impact of metabolic dysfunction on treatment responses to nucleos(t)ide analogues in chronic hepatitis B: a retrospective multi-center REAL-B cohort study Open
View article: Quantification of liver steatosis of metabolic dysfunction-associated steatotic liver disease based on body composition analysis
Quantification of liver steatosis of metabolic dysfunction-associated steatotic liver disease based on body composition analysis Open
Background/Aims Liver steatosis can be measured with ultrasound techniques such as the controlled attenuation parameter (CAP) on an equipped FibroScan. For more widespread screening and quantitative evaluation of liver steatosis, a predict…
View article: Hepatocellular Carcinoma Surveillance and Survival in a Contemporary Asia-Pacific Cohort
Hepatocellular Carcinoma Surveillance and Survival in a Contemporary Asia-Pacific Cohort Open
Importance The etiologies of hepatocellular carcinoma (HCC) are changing. It is unclear whether the benefit of surveillance for people with HCC remains consistent given the changing etiologies of the disease. Objective To evaluate the asso…
View article: The Rising Global Burden of MASLD and Other Metabolic Diseases (2000–2021)
The Rising Global Burden of MASLD and Other Metabolic Diseases (2000–2021) Open
Background Metabolic diseases are a public health threat to diverse populations worldwide. This study aims to update the epidemiological trends of metabolic diseases across regions and sociodemographic stratifications using the Global Burd…
View article: Status of hepatitis B virus and hepatitis C elimination in Singapore: a call for action
Status of hepatitis B virus and hepatitis C elimination in Singapore: a call for action Open
View article: Meta‐Analysis: Effects of Steatotic Liver Disease‐Associated Genetic Risk Alleles on Longitudinal Outcomes
Meta‐Analysis: Effects of Steatotic Liver Disease‐Associated Genetic Risk Alleles on Longitudinal Outcomes Open
Background Genetic variants associated with risk of steatotic liver disease (SLD) may also influence clinical events. Aims To perform a systematic review and meta‐analysis to determine the impact of SLD‐associated genetic variants on hepat…
View article: Open Access to Antipsychotics in State Medicaid Programs: Effect on Healthcare Resource Utilization and Costs among Patients with Serious Mental Illness
Open Access to Antipsychotics in State Medicaid Programs: Effect on Healthcare Resource Utilization and Costs among Patients with Serious Mental Illness Open
Background The restrictive consequences of Medicaid formulary restriction policies on antipsychotic medications may lead to higher healthcare utilization and costs among beneficiaries with serious mental illness (SMI). Objectives This stud…
View article: Head‐to‐Head Comparison of Long‐Term HCC Risk of Antivirals‐Treated Versus Untreated Low‐Level Viremia in HBV‐Compensated Cirrhosis
Head‐to‐Head Comparison of Long‐Term HCC Risk of Antivirals‐Treated Versus Untreated Low‐Level Viremia in HBV‐Compensated Cirrhosis Open
Background Among patients with hepatitis B virus (HBV)‐infected compensated cirrhosis and low‐level viremia, there are limited data for comparative outcomes between those treated with oral nucleos(t)ide analogs versus those not. We conduct…
View article: Sex disparities in alcohol-associated liver disease and subtype differences in alcohol-attributable cancers in the United States
Sex disparities in alcohol-associated liver disease and subtype differences in alcohol-attributable cancers in the United States Open
Background/Aims: Harmful alcohol use is a substantial contributor to liver diseases, liver cancer, and extrahepatic neoplasms. Patterns of alcohol consumption have shifted over recent decades. This study evaluates trends in alcohol-associa…
View article: Impacts of metabolic syndrome diseases on long-term outcomes of chronic hepatitis B patients treated with nucleos(t)ide analogues
Impacts of metabolic syndrome diseases on long-term outcomes of chronic hepatitis B patients treated with nucleos(t)ide analogues Open
Background/Aims: Given the increase in prevalence of metabolic diseases, we investigated their long-term impacts on the outcomes of chronic hepatitis B (CHB) patients receiving nucleos(t)ide analogue (NA) treatment.Methods: We analyzed dat…
View article: Direct-acting antiviral attained sustained virological response improve overall survival in patients with HCV-related hepatocellular carcinoma
Direct-acting antiviral attained sustained virological response improve overall survival in patients with HCV-related hepatocellular carcinoma Open
View article: The Global Burden of Cirrhosis and Other Chronic Liver Diseases in 2021
The Global Burden of Cirrhosis and Other Chronic Liver Diseases in 2021 Open
Background and Aim The burden of cirrhosis and other chronic liver diseases has changed in recent years due to shifts in the contributing aetiologies. We estimated the burden of cirrhosis and other chronic liver diseases, including etiolog…
View article: Burden of alcohol use disorder, alcohol-related liver disease, and alcohol-related liver cancer: Editorial on “Global epidemiology of alcohol-related liver disease, liver cancer, and alcohol use disorder, 2000–2021
Burden of alcohol use disorder, alcohol-related liver disease, and alcohol-related liver cancer: Editorial on “Global epidemiology of alcohol-related liver disease, liver cancer, and alcohol use disorder, 2000–2021 Open
View article: Comparison of pharmacological therapies in metabolic dysfunction–associated steatohepatitis for fibrosis regression and MASH resolution: Systematic review and network meta-analysis
Comparison of pharmacological therapies in metabolic dysfunction–associated steatohepatitis for fibrosis regression and MASH resolution: Systematic review and network meta-analysis Open
Background and Aims: Metabolic dysfunction–associated steatohepatitis (MASH) is a leading cause of liver disease. With the advent of multiple therapeutic targets in late-phase clinical drug development for MASH, there is a knowledge gap to…
View article: Pictorial review of ischaemic hepatitis and its mimics
Pictorial review of ischaemic hepatitis and its mimics Open
View article: Open Access to Antipsychotics in State Medicaid Programs: Effect on Healthcare Resource Utilization and Costs among Patients with Serious Mental Illness
Open Access to Antipsychotics in State Medicaid Programs: Effect on Healthcare Resource Utilization and Costs among Patients with Serious Mental Illness Open
Background: The restrictive consequences of Medicaid formulary restriction policies on antipsychotic medications may lead to higher healthcare utilization and costs among beneficiaries with serious mental illness (SMI). Objectives: This st…
View article: Vibration-controlled transient elastography in shaping the epidemiology and management of steatotic liver disease: Editorial on “Current burden of steatotic liver disease and fibrosis among adults in the United States, 2017–2023”
Vibration-controlled transient elastography in shaping the epidemiology and management of steatotic liver disease: Editorial on “Current burden of steatotic liver disease and fibrosis among adults in the United States, 2017–2023” Open
View article: Sex differences in hepatocellular carcinoma
Sex differences in hepatocellular carcinoma Open
Disparities in the prevalence, progression and prognosis of hepatocellular carcinoma between males and females are well documented, which stem from a complex interplay of various factors. Sex-specific lifestyle, behavioral and psycho-socio…
View article: High-Dimensional Gaussian Process Regression with Soft Kernel Interpolation
High-Dimensional Gaussian Process Regression with Soft Kernel Interpolation Open
We introduce Soft Kernel Interpolation (SoftKI), a method that combines aspects of Structured Kernel Interpolation (SKI) and variational inducing point methods, to achieve scalable Gaussian Process (GP) regression on high-dimensional datas…
View article: Prevalence and longitudinal effects on mortality associated with spectrum of alcohol intake in steatotic liver disease: a United States population study
Prevalence and longitudinal effects on mortality associated with spectrum of alcohol intake in steatotic liver disease: a United States population study Open
ALD predominant patients have higher all-cause and cancer-related mortality risks than MASLD predominant patients but not CVD-related mortality. SLD is highly heterogeneous in clinical characteristics, prevalence, and mortality risks which…
View article: Editorial: Cardiometabolic criteria matters in<scp>MASLD</scp>
Editorial: Cardiometabolic criteria matters in<span>MASLD</span> Open
LINKED CONTENT This article is linked to Tamaki et al papers. To view these articles, visit https://doi.org/10.1111/apt.18205 and https://doi.org/10.1111/apt.18243
View article: The Rising Burden of Hepatocellular Carcinoma: Is the Gender Gap Narrowing?
The Rising Burden of Hepatocellular Carcinoma: Is the Gender Gap Narrowing? Open
HCC: is the gender gap narrowing? of lifestyle modifications