Explanipedia

Transfusion of Fresh Frozen Plasma and Platelets in Critically Ill Adults Open

Angel Coz Yataco, Israa Soghier, Paul C. Hébert, Emilie P. Belley‐Côté, Margaret Disselkamp , et al. · 2025

Red Blood Cell Transfusion in Critically Ill Adults Open

Angel Coz Yataco, Israa Soghier, Paul C. Hébert, Emilie P. Belley‐Côté, Margaret Disselkamp , et al. · 2024

Association of Area Deprivation Index with Adherence to Proposed Regimen in Patients with Sarcoidosis in Detroit, Michigan. Open

Medha Cherabuddi, Benjamin Goodman, Asem Ayyad, Dina Aljbour Almajali, Owais Nadeem , et al. · 2024

We identified intricate patterns of sociodemographic variables affecting access to care in sarcoidosis patients, especially higher ADI national associated with failure to adhere to the proposed regimen, raising concerns for potential healt…

Tocilizumab Associated With Survival in Patients Hospitalized for COVID-19 Acute Respiratory Distress Syndrome and Low Urine Output Open

Raef Fadel, Ashley Scott, Austin Parsons, Ivanna Murskyj, Nour Nasiri , et al. · 2023

Background Acute respiratory distress syndrome (ARDS) with oliguria is associated with increased mortality. Interleukin-6 (IL-6) plays an integral role in the pathophysiology of both disease processes. Patients who experience severe COVID-…

Oliguria on the Day of Intubation Is Associated With Mortality in Patients With Acute Respiratory Distress Syndrome Open

Raef Fadel, Ivanna Murskyj, Elian Abou Asala, Nour Nasiri, Ayman Alsaadi , et al. · 2022

OBJECTIVES: To investigate the relationship between oliguric acute kidney injury (AKI) and mortality in patients with acute respiratory distress syndrome (ARDS). DESIGN: Retrospective cohort study. SETTING: This investigation took place at…

Extreme Elevation of Creatine Kinase in a Young Male Patient With Recurrent Rhabdomyolysis Open

Layla Al Bizri, Anh Do, Daniel R. Ouellette · 2022

Rhabdomyolysis is a common cause of admission to the intensive care unit. However, recurrent rhabdomyolysis remains a rare encounter for intensivists and presents a challenge in terms of identifying its etiology. Considerations of metaboli…

WASOG statement on the diagnosis and management of sarcoidosis-associated pulmonary hypertension Open

Laurent Savale, Marloes P. Huitema, Oksana A. Shlobin, Vasileios Kouranos, Steven D. Nathan , et al. · 2022

Sarcoidosis-associated pulmonary hypertension (SAPH) is an important complication of advanced sarcoidosis. Over the past few years, there have been several studies dealing with screening, diagnosis and treatment of SAPH. This includes the …

Table of Contents Open

David Griffith, Charles L. Daley, Valerie R. Wiersma, Simon D. Pouwels, Daniel R. Ouellette , et al. · 2022

SARCOIDOSIS AND HYPERCALCIURIA: A STONE COLD INDICATION FOR TREATMENT Open

RAJANINDER SHARMA, Jonathan Gwizdala, Daniel R. Ouellette · 2021

OUTCOMES IN PATIENTS WITH SARCOIDOSIS DIAGNOSED WITH COVID-19 Open

Owais Nadeem, Amreeta Sharma, Diana Alaouie, Patrick Bradley, Daniel R. Ouellette · 2021

MECHANICAL VENTILATION AND COVID-19: A CASE-CONTROL ANALYSIS OF CLINICAL CHARACTERISTICS, LUNG MECHANICS, AND MORTALITY Open

ALAA ABU SAYF, Daniel R. Ouellette, Raef Fadel · 2021

ERS clinical practice guidelines on treatment of sarcoidosis Open

Robert P. Baughman, Dominique Valeyre, Peter Korsten, Alexander G. Mathioudakis, Wim Wuyts , et al. · 2021

Background The major reasons to treat sarcoidosis are to lower the morbidity and mortality risk or to improve quality of life (QoL). The indication for treatment varies depending on which manifestation is the cause of symptoms: lungs, hear…

Mechanical Ventilation and Coronavirus Disease 2019: A Case-Control Analysis of Clinical Characteristics, Lung Mechanics, and Mortality Open

Alaa Abu Sayf, Raef Fadel, Ashley Scott, Layla Al Bizri, Wing Tai Kong , et al. · 2021

Objectives: To investigate the differences in clinical course, ventilator mechanics, and outcomes of patients with coronavirus disease 2019 secondary to acute respiratory distress syndrome infection compared with a historical cohort of acu…

The association between cumulative dose of inhaled bronchodilators and mortality in patients with severe ARDS Open

Ashley Scott, Raef Fadel, Elian D Abou Asala, I.O. Murskyi, Julia Bachler , et al. · 2021

Background: The purpose of this study was to examine bronchodilator use in patients with severe acute respiratory distress syndrome (ARDS) to determine if such use affected mortality. We compared cohorts of patients receiving and not recei…

2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group Open

Michelle M. Cloutier, Alan P. Baptist, Kathryn Blake, Edward G. Brooks, Tyra Bryant-Stephens , et al. · 2020

MORTALITY AND OUTCOMES OF PATIENTS WITH ARDS ON VENOVENOUS EXTRACORPOREAL MEMBRANE OXYGENATION FOLLOWING IMPLEMENTATION OF A COMPREHENSIVE CARE TEAM Open

Vritti Gupta, Bathmapriya Balakrishnan, Daniel R. Ouellette, Jayna Gardner-Gray, Jeffrey Jennings · 2020

The Use of Bronchoscopy During the Coronavirus Disease 2019 Pandemic Open

Momen M. Wahidi, Samira Shojaee, Carla Lamb, David E. Ost, Fabien Maldonado , et al. · 2020

A FATAL CASE OF HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS DUE TO EXTRA-PULMONARY SARCOIDOSIS Open

Dania Shakaroun, Hassan Nasser, Daniel R. Ouellette · 2019

INHALED BETA-2 AGONIST THERAPY IN MODERATE-TO-SEVERE ARDS: A MULTI-CENTER RETROSPECTIVE COHORT STUDY Open

Ashley Scott, Daniel R. Ouellette · 2019

Risk factors for respiratory hospitalizations in a population of patients with a clinical diagnosis of COPD Open

Jovica Veljanovski, Daniel R. Ouellette · 2018

In a clinically diagnosed COPD population who had spirometry performed, the presence of airflow obstruction was not a risk factor for respiratory hospitalizations. The most significantly associated nontreatment factor associated with respi…

Clinical Practice Guideline: Hoarseness (Dysphonia) (Update) Executive Summary Open

Robert J. Stachler, David O. Francis, Seth Schwartz, Cecelia Damask, G. Paul Digoy , et al. · 2018

Objective This guideline provides evidence‐based recommendations on treating patients presenting with dysphonia, which is characterized by altered vocal quality, pitch, loudness, or vocal effort that impairs communication and/or quality of…

Clinical Practice Guideline: Hoarseness (Dysphonia) (Update) Open

Robert J. Stachler, David O. Francis, Seth Schwartz, Cecelia Damask, G. Paul Digoy , et al. · 2018

Objective This guideline provides evidence‐based recommendations on treating patients who present with dysphonia, which is characterized by altered vocal quality, pitch, loudness, or vocal effort that impairs communication and/or quality o…

Response Open

Daniel R. Ouellette, Sheena Patel, Timothy D. Girard, Gregory A. Schmidt, Jonathon D. Truwit , et al. · 2017

Recognition, diagnosis, and treatment of cognitive and psychiatric disorders in patients with COPD Open

Daniel R. Ouellette, Kim Lavoie · 2017

COPD is highly prevalent and associated with substantial morbidity and mortality. Clinicians have long been aware that patients with COPD have problems with cognition and are susceptible to mood (depression) and anxiety disorders. With the…

New Developments in Mechanical Ventilation Open

Daniel R. Ouellette · 2017

Positive pressure ventilation was developed in the 1950s as a way to treat respiratory failure due to ventilatory insufficiency. While lifesaving, mechanical ventilation, especially when prolonged, can be associated with a host of complica…

Liberation From Mechanical Ventilation in Critically Ill Adults Open

Gregory A. Schmidt, Timothy D. Girard, John P. Kress, Peter E. Morris, Daniel R. Ouellette , et al. · 2016

A Rare Case of Pulmonary Plasmacytoma Secondary to Multiple Myeloma Open

Mohamed Rezik, Jesse Onyenekwe, Rashad Farha, Daniel R. Ouellette · 2016

Potential Protective Effect of PPI in COPD Open

Rashad Farha, Muhammad Usman, Chaun M. Gandolfo, Amber Smith, Daniel R. Ouellette · 2016

“Ping-pong gaze” secondary to monoamine oxidase inhibitor overdose Open

Amy Attaway, Laila Sroujieh, Tracey L. Mersfelder, Christopher Butler, Daniel R. Ouellette · 2016

An infrequent manifestation of monoamine oxidase inhibitor (MAOI) toxicity is "ping-pong gaze" (PPG). We describe the case of a 26-year-old female who was found unresponsive after taking 40 tablets of phenelzine. On presentation to the hos…

Sepsis outcomes in patients receiving statins prior to hospitalization for sepsis: comparison of in-hospital mortality rates between patients who received atorvastatin and those who received simvastatin Open

Daniel R. Ouellette, Erics Espinoza Moscoso, Julio Pinto Corrales, Michael A. Peters · 2015

Pre-hospital atorvastatin use was associated with improved in-hospital mortality in septic patients when compared with pre-hospital simvastatin use and was independently associated with an improved outcome when compared to other sepsis ris…

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