Daniel Schuetzmann
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View article: Benchmarking of 4C-seq pipelines based on real and simulated data
Benchmarking of 4C-seq pipelines based on real and simulated data Open
Motivation With its capacity for high-resolution data output in one region of interest, chromosome conformation capture combined with high-throughput sequencing (4C-seq) is a state-of-the-art next-generation sequencing technique that provi…
View article: Temporal autoregulation during human PU.1 locus SubTAD formation
Temporal autoregulation during human PU.1 locus SubTAD formation Open
Epigenetic control of gene expression occurs within discrete spatial chromosomal units called topologically associating domains (TADs), but the exact spatial requirements of most genes are unknown; this is of particular interest for genes …