Daniel Schulze
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View article: Using Item Response Theory Models in Scaling Severity Scores in Alcohol Research—A Tutorial
Using Item Response Theory Models in Scaling Severity Scores in Alcohol Research—A Tutorial Open
Introduction Questionnaires are frequently used in the assessment of drug and alcohol dependence. Methods Typically, sum scores are used for aggregation, which come with several underlying assumptions. If untested psychometrically, the rel…
View article: Digital health literacy among people with bipolar disorder in Germany – a cross-sectional survey
Digital health literacy among people with bipolar disorder in Germany – a cross-sectional survey Open
Background This study assesses digital health literacy (DHL) among individuals with bipolar disorder (BD) in Germany, employing Sørensen’s Integrated Model of Health Literacy (SIMHL). According to SIMHL, health literacy is a dynamic constr…
View article: Calprotectin and neurofilament serum levels correlate with treatment response in myasthenia gravis under intensified therapy–A pilot study
Calprotectin and neurofilament serum levels correlate with treatment response in myasthenia gravis under intensified therapy–A pilot study Open
Our preliminary findings suggest that markers of systemic inflammation (such as sCLP) and local destruction of the neuromuscular junction (such as sNfL) may assist in treatment decision-making for gMG patients. Larger, multicenter studies …
View article: Randomized Controlled Preclinical Trial of a Benzodiazepine–Dihydropyridine Hybrid Molecule in Rodent Stroke
Randomized Controlled Preclinical Trial of a Benzodiazepine–Dihydropyridine Hybrid Molecule in Rodent Stroke Open
Background The 3‐ethoxycarbonyl‐2‐methyl‐4‐(2‐nitrophenyl)‐4,11‐dihydro‐1H‐pyrido[2,3‐b][1,5]benzodiazepine (JM‐20) molecule is a novel multifunctional molecule with potent neuroprotective effects in rat focal cerebral ischemia. To confirm…
View article: A Retrospective Cohort Study of the GLA c.937G > T, p.Asp313Tyr Variant With No Evidence of an Association With Fabry Disease
A Retrospective Cohort Study of the GLA c.937G > T, p.Asp313Tyr Variant With No Evidence of an Association With Fabry Disease Open
GLA variant p.Asp313Tyr is to be classified as a benign variant and does not cause FD. Because an enrichment of patients with this variant in specific high-risk populations has been seen in this cohort and by other groups, properly …
View article: Erenumab for Chronic Cluster Headache
Erenumab for Chronic Cluster Headache Open
Importance Calcitonin gene-related peptide (CGRP) is involved in the pathophysiology of cluster headache (CH). Prophylactic pharmacologic treatment options for chronic CH (CCH) are limited. The potential effects of erenumab, a CGRP recepto…
View article: Negative symptomatology and clozapine-induced obsessive–compulsive symptoms: a cross-sectional analysis
Negative symptomatology and clozapine-induced obsessive–compulsive symptoms: a cross-sectional analysis Open
Obsessive–compulsive symptoms (OCS) frequently manifest in individuals with schizophrenia, affecting their prognosis and quality of life. The etiology of OCS in schizophrenia is complex, with theories ranging from subtype-specific manifest…
View article: A Two‐Step Risk Score for Prediction of Permanent Pacemaker Implantation After Transcatheter Aortic Valve Implantation
A Two‐Step Risk Score for Prediction of Permanent Pacemaker Implantation After Transcatheter Aortic Valve Implantation Open
Background The need for postoperative permanent pacemaker implantation (PPMI) remains one of the most frequent complications after transcatheter aortic valve implantation (TAVI). This study aimed to develop a novel, 2‐step risk score to pr…
View article: Post-infection symptoms up to 24 months after COVID-19: a matched cohort study in Berlin, Germany
Post-infection symptoms up to 24 months after COVID-19: a matched cohort study in Berlin, Germany Open
Introduction Long-term health consequences after mild COVID-19 are not well described. Our aim was to estimate their prevalence and describe the time course of signs and symptoms for a period of up to 24 months after SARS-CoV-2 infection. …
View article: Cognitive behavioural therapy plus Kiesler Circle Training (CBT+) versus CBT only for patients with interpersonal problems: study protocol for a randomised controlled feasibility trial
Cognitive behavioural therapy plus Kiesler Circle Training (CBT+) versus CBT only for patients with interpersonal problems: study protocol for a randomised controlled feasibility trial Open
Introduction Interpersonal problems are a transdiagnostic risk factor for the development and maintenance of various psychiatric disorders, including anxiety and depression. Interventions that address these interpersonal challenges could t…
View article: Long-term effects of tocilizumab on retinal and choroidal inflammation in Birdshot uveitis
Long-term effects of tocilizumab on retinal and choroidal inflammation in Birdshot uveitis Open
View article: Post-infection symptoms up to 24 months after COVID-19: a matched cohort study in Berlin, Germany
Post-infection symptoms up to 24 months after COVID-19: a matched cohort study in Berlin, Germany Open
Background Long-term health consequences after mild COVID-19 are not well described. Our aim was to estimate their prevalence and describe the time course of signs and symptoms for a period of up to 24 months after confirmed SARS-CoV-2 inf…
View article: Percutaneous Cryoablation in the Liver: A Meta-Analysis and Review of Safety with a Focus on Incidence of Cryoshock and Major Complications
Percutaneous Cryoablation in the Liver: A Meta-Analysis and Review of Safety with a Focus on Incidence of Cryoshock and Major Complications Open
Purpose The aim of the present meta-analysis was to systematically determine the overall complication rate and incidence of cryoshock in patients undergoing cryoablation of the liver. Methods A systematic review and meta-analysis adhering …
View article: Distal versus proximal radial access in coronary angiography: a meta-analysis
Distal versus proximal radial access in coronary angiography: a meta-analysis Open
Background Distal radial access (DRA) represents a promising alternative to conventional proximal radial access (PRA) for coronary angiography. Substantial advantages regarding safety and efficacy have been suggested for DRA, but the ideal…
View article: Impaired glucose metabolism and the risk of vascular events and mortality after ischemic stroke: A systematic review and meta-analysis
Impaired glucose metabolism and the risk of vascular events and mortality after ischemic stroke: A systematic review and meta-analysis Open
Background Diabetes mellitus (DM), prediabetes, and insulin resistance are highly prevalent in patients with ischemic stroke (IS). DM is associated with higher risk for poor outcomes after IS. Objective Investigate the risk of recurrent va…
View article: TAVI PACER: A two-step risk score for prediction of permanent pacemaker implantation after TAVI.
TAVI PACER: A two-step risk score for prediction of permanent pacemaker implantation after TAVI. Open
Background: The need for permanent pacemaker implantation (PPMI) remains one of the most frequent complications after transcatheter aortic valve implantation (TAVI). This study aimed to develop a novel, two-step risk score to predict PPMI …
View article: Factors Associated With Risky Drinking Decisions in a Virtual Reality Alcohol Prevention Simulation: Structural Equation Model
Factors Associated With Risky Drinking Decisions in a Virtual Reality Alcohol Prevention Simulation: Structural Equation Model Open
Background Risky alcohol consumption among adolescents is a significant public health concern in most Western countries. Various motives and factors (eg, sensation seeking, gender, reduced self-efficacy) known in the literature are associa…
View article: TAVI PACER - a contemporary risk score for pacemaker implantation after TAVI
TAVI PACER - a contemporary risk score for pacemaker implantation after TAVI Open
Background The need for permanent pacemaker implantation (PPM) remains one of the most frequent complications of transcatheter aortic valve implantation (TAVI). The aim of this study was to develop a novel risk score for the prediction of …
View article: A randomized, controlled, two-center preclinical trial assessing the efficacy of a new benzodiazepine–dihydropyridine hybrid molecule (JM-20) in rodent models of ischemic stroke
A randomized, controlled, two-center preclinical trial assessing the efficacy of a new benzodiazepine–dihydropyridine hybrid molecule (JM-20) in rodent models of ischemic stroke Open
JM-20 is a novel multifunctional benzodiazepine molecule with potent neuroprotective effects in rat focal cerebral ischemia. To confirm previous results obtained in single laboratories with small sample sizes, and to provide a robust precl…
View article: Impact of Coronavirus Disease 2019 (COVID-19) Pandemic on Surgical Site Infection in Patients with Inflammatory Bowel Disease—A Monocentric, Retrospective Cohort Study
Impact of Coronavirus Disease 2019 (COVID-19) Pandemic on Surgical Site Infection in Patients with Inflammatory Bowel Disease—A Monocentric, Retrospective Cohort Study Open
(1) Background: Surgical site infections (SSIs) are a relevant problem with a 25% incidence rate after elective laparotomy due to inflammatory bowel disease (IBD). The aim of this study was to evaluate whether stricter hygienic measures du…
View article: Factors Associated With Risky Drinking Decisions in a Virtual Reality Alcohol Prevention Simulation: Structural Equation Model (Preprint)
Factors Associated With Risky Drinking Decisions in a Virtual Reality Alcohol Prevention Simulation: Structural Equation Model (Preprint) Open
BACKGROUND Risky alcohol consumption among adolescents is a significant public health concern in most Western countries. Various motives and factors (eg, sensation seeking, gender, reduced self-efficacy) known in the literature are associ…
View article: P219: Genetic, biochemical and clinical properties of GLA p.Asp313Tyr variant in a large German cohort
P219: Genetic, biochemical and clinical properties of GLA p.Asp313Tyr variant in a large German cohort Open
Fabry disease (FD; OMIM 301500) is an inborn error of metabolism, caused by pathogenic variants in the GLA gene (OMIM 300644) and resulting in a deficiency of the lysosomal enzyme α-galactosidase A (AGLA) with progressive accumulation of g…
View article: Patient perspective on task shifting from general practitioners to medical practice assistants – a quantitative survey in Germany
Patient perspective on task shifting from general practitioners to medical practice assistants – a quantitative survey in Germany Open
View article: Measurement Invariance Widely Holds for the Yale-Brown Obsessive Compulsive Scale
Measurement Invariance Widely Holds for the Yale-Brown Obsessive Compulsive Scale Open
The clinician-rated Yale-Brown Obsessive Compulsive Scale (Y-BOCS) is a widely used assessment tool for obsessive-compulsive disorder (OCD). However, the measurement invariance (MI) properties of the Y-BOCS, a prerequisite for group or tim…
View article: Outcome and management of decompressive hemicraniectomy in malignant hemispheric stroke following cardiothoracic surgery
Outcome and management of decompressive hemicraniectomy in malignant hemispheric stroke following cardiothoracic surgery Open
View article: The EnMAP imaging spectroscopy mission towards operations
The EnMAP imaging spectroscopy mission towards operations Open
EnMAP (Environmental Mapping and Analysis Program) is a high-resolution imaging spectroscopy remote sensing mission that was successfully launched on April 1st, 2022. Equipped with a prism-based dual-spectrometer, EnMAP performs observatio…
View article: Die hausärztliche Versorgung während der COVID-19-Pandemie: eine Fragebogenerhebung unter Hausärzt*innen und Medizinischen Fachangestellten zu ihrer Perspektive auf Veränderungen, Bedarfe und Belastungen
Die hausärztliche Versorgung während der COVID-19-Pandemie: eine Fragebogenerhebung unter Hausärzt*innen und Medizinischen Fachangestellten zu ihrer Perspektive auf Veränderungen, Bedarfe und Belastungen Open
The subjective view of general practitioners and medical practice assistants on their health care provision shows that appreciation and adequate financial renumeration, particularly when working under most difficult conditions, are necessa…
View article: Mechanisms of exposure and response prevention in obsessive-compulsive disorder: effects of habituation and expectancy violation on short-term outcome in cognitive behavioral therapy
Mechanisms of exposure and response prevention in obsessive-compulsive disorder: effects of habituation and expectancy violation on short-term outcome in cognitive behavioral therapy Open
View article: The unique Cr-rich megacryst suite from the Sloan kimberlite, Colorado: Comparison with other so-called “Cr-rich megacryst suites”
The unique Cr-rich megacryst suite from the Sloan kimberlite, Colorado: Comparison with other so-called “Cr-rich megacryst suites” Open
View article: Behaviour of S and Fe during multi-stage metasomatism of oceanic crust as revealed by eclogite xenoliths from the Colorado Plateau
Behaviour of S and Fe during multi-stage metasomatism of oceanic crust as revealed by eclogite xenoliths from the Colorado Plateau Open