Daniel H. Solomon
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View article: Three‐Year Results of Tapering Tumor Necrosis Factor Inhibitor to Withdrawal Compared to Stable Tumor Necrosis Factor Inhibitor Among Patients With Rheumatoid Arthritis in Sustained Remission: A Multicenter Randomized Trial
Three‐Year Results of Tapering Tumor Necrosis Factor Inhibitor to Withdrawal Compared to Stable Tumor Necrosis Factor Inhibitor Among Patients With Rheumatoid Arthritis in Sustained Remission: A Multicenter Randomized Trial Open
Objective Tapering of tumor necrosis factor inhibitor (TNFi) treatment in rheumatoid arthritis (RA) remission is debated. We assessed the effect of tapering TNFi to withdrawal versus continued stable TNFi on flare‐free survival and joint d…
View article: Tailoring Rheumatoid Arthritis Visit Timing Based on mHealth App Data: Mixed Methods Assessment of Implementation and Usability
Tailoring Rheumatoid Arthritis Visit Timing Based on mHealth App Data: Mixed Methods Assessment of Implementation and Usability Open
Background Visits to medical subspecialists are common, with follow-up timing often based on heuristics rather than evidence. Unnecessary visits contribute to long wait times for new patients. Specialists could enhance visit timing and red…
View article: ChatGPT, et al … Artificial Intelligence, Authorship, and Medical Publishing
ChatGPT, et al … Artificial Intelligence, Authorship, and Medical Publishing Open
If you have not yet heard of ChatGPT, you will! This artificial intelligence (AI)-based chatbot is making waves in medicine, education, academic publishing, and more widely. If you are a clinician and dismissed the idea that AI-powered ca…
View article: The Design of a Randomized Controlled Active Comparator Strategy Trial for Gout: Treat to Target Serum Urate Versus Treat to Avoid Symptoms
The Design of a Randomized Controlled Active Comparator Strategy Trial for Gout: Treat to Target Serum Urate Versus Treat to Avoid Symptoms Open
Objective Controversy persists regarding the optimal management of gout in routine primary care. There is a lack of clarity on whether treating to a target serum urate (TTT‐SU) versus treating to avoid symptoms (TTASx) is more effective. M…
View article: Longitudinal Assessment of Pain in Rheumatoid Arthritis: Increases in Pain and Their Relationship to Functional Declines and Medication Changes
Longitudinal Assessment of Pain in Rheumatoid Arthritis: Increases in Pain and Their Relationship to Functional Declines and Medication Changes Open
Objective Electronic health applications (apps) allow patients with rheumatoid arthritis (RA) to report patient‐reported outcomes (PROs) between visits. However, almost no data exist on patients’ report of pain between visits and how that …
View article: Lessons Learned: Overcoming Obstacles to Inference and Synthesis in Atrocity Prevention Research
Lessons Learned: Overcoming Obstacles to Inference and Synthesis in Atrocity Prevention Research Open
In this paper, we argue that atrocity prevention (AP) researchers face obstacles to inference and knowledge synthesis in the study of AP strategies and tools. We argue that researchers can begin to address obstacles to inference by using r…
View article: Diabetes and Uterine Fibroid Diagnosis in Midlife: Study of Women's Health Across the Nation (SWAN)
Diabetes and Uterine Fibroid Diagnosis in Midlife: Study of Women's Health Across the Nation (SWAN) Open
Context Fibroids are noncancerous uterine tumors potentially associated with cardiovascular risk factors. Objective We aimed to examine prospectively associations of glucose, insulin, sex hormone–binding globulin (SHBG), and diabetes with …
View article: Returning Incidental Research Findings From <scp><sup>18</sup>F</scp>‐Fluorodeoxyglucose–Positron Emission Tomography/Computed Tomography to Participants: A Survey of Investigators From a Clinical Trial of Rheumatoid Arthritis
Returning Incidental Research Findings From <span><sup>18</sup>F</span>‐Fluorodeoxyglucose–Positron Emission Tomography/Computed Tomography to Participants: A Survey of Investigators From a Clinical Trial of Rheumatoid Arthritis Open
Objective There are limited data on researchers’ attitudes and beliefs on returning and managing incidental research findings from whole body 18 F‐fluorodeoxyglucose–positron emission tomography/computed tomography (FDG PET/CT) imaging. Me…
View article: Agreement between patient-reported flares and clinically significant flare status in patients with rheumatoid arthritis in sustained remission: data from the ARCTIC REWIND trials
Agreement between patient-reported flares and clinically significant flare status in patients with rheumatoid arthritis in sustained remission: data from the ARCTIC REWIND trials Open
Objectives To explore the agreement between patient-reported flare status and clinically significant flare status in patients with rheumatoid arthritis (RA) in sustained remission. Method Patients with RA in remission for ≥12 months on sta…
View article: Longitudinal analysis of serum urate in prediabetic phase
Longitudinal analysis of serum urate in prediabetic phase Open
Objectives Despite the well-established association between prediabetes and hyperuricaemia, knowledge about serum urate (SU) trends during the prediabetic phase is limited. Therefore, we aimed to assess the longitudinal changes of SU in in…
View article: Impact of RA treatment strategies on lipids and vascular inflammation in rheumatoid arthritis: a secondary analysis of the TARGET randomized active comparator trial
Impact of RA treatment strategies on lipids and vascular inflammation in rheumatoid arthritis: a secondary analysis of the TARGET randomized active comparator trial Open
Background Treatments for rheumatoid arthritis (RA) are associated with complex changes in lipids and lipoproteins that may impact cardiovascular (CV) risk. The objective of this study was to examine lipid and lipoprotein changes associate…
View article: Brain implantation of tissue-level-soft bioelectronics via embryonic development
Brain implantation of tissue-level-soft bioelectronics via embryonic development Open
The design of bioelectronics capable of stably tracking brain-wide, single-cell, and millisecond-resolved neural activities in the developing brain is critical to the study of neuroscience and neurodevelopmental disorders. During developme…
View article: Interplay Between Systemic Inflammation, Myocardial Injury, and Coronary Microvascular Dysfunction in Rheumatoid Arthritis: Results From the LiiRA Study
Interplay Between Systemic Inflammation, Myocardial Injury, and Coronary Microvascular Dysfunction in Rheumatoid Arthritis: Results From the LiiRA Study Open
Background Coronary microvascular dysfunction as measured by myocardial flow reserve (MFR) is associated with increased cardiovascular risk in rheumatoid arthritis (RA). The objective of this study was to determine the association between …
View article: Association of the multi-biomarker disease activity score with arterial 18-fluorodeoxyglucose uptake in rheumatoid arthritis
Association of the multi-biomarker disease activity score with arterial 18-fluorodeoxyglucose uptake in rheumatoid arthritis Open
Objectives Rheumatoid arthritis (RA) and atherosclerosis share many common inflammatory pathways. We studied whether a multi-biomarker panel for RA disease activity (MBDA) would associate with changes in arterial inflammation in an interve…
View article: Hypertension, Cardiovascular Risk Factors, and Uterine Fibroid Diagnosis in Midlife
Hypertension, Cardiovascular Risk Factors, and Uterine Fibroid Diagnosis in Midlife Open
Importance Fibroids are benign neoplasms associated with severe gynecologic morbidity. There are no strategies to prevent fibroid development. Objective To examine associations of hypertension, antihypertensive treatment, anthropometry, an…
View article: Biomarkers of Cardiovascular Risk in Patients With Rheumatoid Arthritis: Results From the TARGET Trial
Biomarkers of Cardiovascular Risk in Patients With Rheumatoid Arthritis: Results From the TARGET Trial Open
A candidate biomarker approach identified several promising biomarkers that associate with baseline and treatment-associated changes in arterial inflammation in patients with RA. These will now be tested in an external validation cohort.
View article: Multinomial extension of propensity score trimming methods: A simulation study
Multinomial extension of propensity score trimming methods: A simulation study Open
Crump et al. (Biometrika. 2009;96(1):187-199), Stürmer et al. (Am J Epidemiol. 2010;172(7):843-854), and Walker et al. (Comp Eff Res. 2013;2013(3):11-20) proposed propensity score (PS) trimming methods as a means to improve efficiency (Cru…
View article: Historical Violence and Public Attitudes towards Justice: Evidence from the United States
Historical Violence and Public Attitudes towards Justice: Evidence from the United States Open
This article brings transitional justice scholarship to bear on the case of racial violence in the United States. We investigate how knowledge of racial terror lynchings shapes Black Americans’ support for symbolic and material transitiona…