Daniel Steinbach
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View article: Data from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia
Data from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia Open
Background: A major issue in the treatment of acute myeloid leukemia (AML) is resistance to chemotherapeutic drugs. Multidrug resistance can be caused by ATP-binding cassette (ABC) transporters that function as drug efflux pumps. The major…
View article: Supplementary Figures 1-2 from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia
Supplementary Figures 1-2 from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia Open
Supplementary Figures 1-2 from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia
View article: Supplementary Figures 1-2 from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia
Supplementary Figures 1-2 from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia Open
Supplementary Figures 1-2 from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia
View article: Data from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia
Data from ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia Open
Background: A major issue in the treatment of acute myeloid leukemia (AML) is resistance to chemotherapeutic drugs. Multidrug resistance can be caused by ATP-binding cassette (ABC) transporters that function as drug efflux pumps. The major…
View article: The Antithetic Roles of IQGAP2 and IQGAP3 in Cancers
The Antithetic Roles of IQGAP2 and IQGAP3 in Cancers Open
The scaffold protein family of IQ motif-containing GTPase-activating proteins (IQGAP1, 2, and 3) share a high degree of homology and comprise six functional domains. IQGAPs bind and regulate the cytoskeleton, interact with MAP kinases and …
View article: Identification of bacteria in mixed infection from urinary tract of patient's samples using Raman analysis of dried droplets
Identification of bacteria in mixed infection from urinary tract of patient's samples using Raman analysis of dried droplets Open
Raman spectroscopy approach based on dried droplets, for mixed UTI bacterial pathogens identification.
View article: Reduced IQGAP2 Promotes Bladder Cancer through Regulation of MAPK/ERK Pathway and Cytokines
Reduced IQGAP2 Promotes Bladder Cancer through Regulation of MAPK/ERK Pathway and Cytokines Open
The progression of non-muscle-invasive bladder cancer (NMIBC) to muscle-invasive bladder cancer (MIBC) is a major challenge in urologic oncology. However, understanding of the molecular processes remains limited. The dysregulation of IQGAP…
View article: Wnt/β-Catenin Signalling and Its Cofactor BCL9L Have an Oncogenic Effect in Bladder Cancer Cells
Wnt/β-Catenin Signalling and Its Cofactor BCL9L Have an Oncogenic Effect in Bladder Cancer Cells Open
Bladder cancer (BC) is characterised by a high recurrence and progression rate. However, the molecular mechanisms of BC progression remain poorly understood. BCL9L, a coactivator of β-catenin was mutated in the 5′ and 3′ untranslated regio…
View article: SLC35F2, a Transporter Sporadically Mutated in the Untranslated Region, Promotes Growth, Migration, and Invasion of Bladder Cancer Cells
SLC35F2, a Transporter Sporadically Mutated in the Untranslated Region, Promotes Growth, Migration, and Invasion of Bladder Cancer Cells Open
Bladder cancer is a very heterogeneous disease and the molecular mechanisms of carcinogenesis and progression are insufficiently investigated. From the DNA sequencing analysis of matched non-muscle-invasive bladder cancer (NMIBC) and muscl…
View article: Rare visual diagnosis in cases of chronic coughing
Rare visual diagnosis in cases of chronic coughing Open
Introduction ENT specialists are often consulted in cases of chronic coughing. Our report relates to a very rare cause of this with very characteristic endoscopy findings.
View article: Tribbles 2 mediates cisplatin sensitivity and DNA damage response in epithelial ovarian cancer
Tribbles 2 mediates cisplatin sensitivity and DNA damage response in epithelial ovarian cancer Open
Aim was to identify methylated genes with functional involvement in cisplatin‐resistance development of epithelial ovarian cancer (EOC). Genome‐wide analyses of hypermethylated CpG‐islands in resistant cell lines in combination with qRT‐PC…