Alex D. Sweeney
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View article: American Cochlear Implant Alliance Position Statement on Newborn Congenital Cytomegalovirus Screening
American Cochlear Implant Alliance Position Statement on Newborn Congenital Cytomegalovirus Screening Open
It is estimated that 1 in every 200 US newborns has congenital cytomegalovirus (cCMV). Delayed identification of cCMV in newborns precludes timely intervention to mitigate sequelae of the infection such as hearing loss and other neurologic…
View article: The Effects of Home Language Use on Spanish Speech Measures in Bilingual Children With Hearing Loss Who Use Cochlear Implants and Their Peers With Normal Hearing
The Effects of Home Language Use on Spanish Speech Measures in Bilingual Children With Hearing Loss Who Use Cochlear Implants and Their Peers With Normal Hearing Open
Purpose: The purpose of this study was to investigate how the amount of home language use between the primary caregiver and bilingual Spanish- and English-speaking children with hearing loss who use cochlear implants (CIs) versus their bil…
View article: Case Report: Contralateral Progression of a Vestibular Schwannoma After Resection in a Patient with Neurofibromatosis Type 2
Case Report: Contralateral Progression of a Vestibular Schwannoma After Resection in a Patient with Neurofibromatosis Type 2 Open
BACKGROUND AND IMPORTANCE: Bilateral vestibular schwannomas (VS) are a distinctive feature of neurofibromatosis type 2 (NF2) that result in a serious reduction in the quality of life for patients. The growth rates of these schwannomas are …
View article: Single-cell multi-omic analysis of the vestibular schwannoma ecosystem uncovers a nerve injury-like state
Single-cell multi-omic analysis of the vestibular schwannoma ecosystem uncovers a nerve injury-like state Open
Vestibular schwannomas (VS) are benign tumors that lead to significant neurologic and otologic morbidity. How VS heterogeneity and the tumor microenvironment (TME) contribute to the pathogenesis of these tumors remains poorly understood. W…
View article: Usefulness of Exam Questions and Vital Signs for Predicting the Outcome of Objective Vestibular Tests
Usefulness of Exam Questions and Vital Signs for Predicting the Outcome of Objective Vestibular Tests Open
Objectives/Hypothesis To determine the value of standard clinic screening questions and vital signs in predicting abnormal vestibular function, indicated by standard objective diagnostic tests. Study Design Retrospective records review. Me…
View article: The Role of Merlin/NF2 Loss in Meningioma Biology
The Role of Merlin/NF2 Loss in Meningioma Biology Open
Mutations in the neurofibromin 2 (NF2) gene were among the first genetic alterations implicated in meningioma tumorigenesis, based on analysis of neurofibromatosis type 2 (NF2) patients who not only develop vestibular schwannomas but later…
View article: Colon cancer metastasis to the lateral skull base masquerading as mastoiditis
Colon cancer metastasis to the lateral skull base masquerading as mastoiditis Open
Temporal bone metastases (TBMs) have most commonly been reported as a consequence of disseminated breast, lung, and prostate malignancy. We present an unusual case of adenocarcinoma of the colon metastatic to the temporal bone and middle c…
View article: Bone Conduction Implants for Hearing Rehabilitation in Skull Base Tumor Patients
Bone Conduction Implants for Hearing Rehabilitation in Skull Base Tumor Patients Open
Bone conduction implants transfer sound to the inner ear through direct vibration of the skull. In patients with skull base tumors and infections, these devices can bypass a dysfunctional ear canal and/or middle ear. Though not all skull b…
View article: A Transient, Postauricular Arteriovenous Fistula Masquerading as Acute Mastoiditis
A Transient, Postauricular Arteriovenous Fistula Masquerading as Acute Mastoiditis Open
Background Vascular lesions of the skull base are diverse in terms of etiology and natural history. Outside of neoplasm, most entities in this category represent congenital or acquired malformations of arteries, veins, or both. In some cas…
View article: Diverticula of the Superior Petrosal Sinus Leading to Superior Semicircular Canal Dehiscence
Diverticula of the Superior Petrosal Sinus Leading to Superior Semicircular Canal Dehiscence Open
Background Since its initial description nearly two decades ago, superior semicircular canal dehiscence (SSCD) has quickly moved to the forefront of research and clinical practice in neurotology. Anatomically, the superior semicircular can…
View article: Temporal Bone Paraganglioma Presenting as a Bezold—s Abscess and Necrotizing Fasciitis
Temporal Bone Paraganglioma Presenting as a Bezold—s Abscess and Necrotizing Fasciitis Open
Background Though paragangliomas of the temporal bone are usually benign histopathologically, locally aggressive behavior can be mistaken for malignancy. Due to the consequences of associated bone erosion in areas of the temporal bone that…
View article: Durability of Hearing Preservation after Cochlear Implantation with Conventional‐Length Electrodes and Scala Tympani Insertion
Durability of Hearing Preservation after Cochlear Implantation with Conventional‐Length Electrodes and Scala Tympani Insertion Open
Objectives To analyze factors that influence hearing preservation over time in cochlear implant recipients with conventional‐length electrode arrays located entirely within the scala tympani. Study Design Case series with planned chart rev…
View article: Impact of Intrascalar Electrode Location, Electrode Type, and Angular Insertion Depth on Residual Hearing in Cochlear Implant Patients
Impact of Intrascalar Electrode Location, Electrode Type, and Angular Insertion Depth on Residual Hearing in Cochlear Implant Patients Open
Scalar excursion is a strong predictor of losing residual hearing. However, neither age, sex, electrode type, nor angular insertion depth was correlated with hearing preservation in the full ST group. Techniques to decrease the risk of ele…
View article: Cochlear implantation: a biomechanical prosthesis for hearing loss
Cochlear implantation: a biomechanical prosthesis for hearing loss Open
Cochlear implants are a medical prosthesis used to treat sensorineural deafness, and one of the greatest advances in modern medicine. The following article is an overview of cochlear implant technology. The history of cochlear implantation…