Daniel K. Wells
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View article: Model Development of the Phenological Cycle from Flower to Fruit of Strawberries (Fragaria × ananassa)
Model Development of the Phenological Cycle from Flower to Fruit of Strawberries (Fragaria × ananassa) Open
Strawberries are a very important economic crop; thus, a lot of research has been conducted on several production areas. However, phenological performance is still lacking information, especially when it comes to modeling. Therefore, this …
View article: Supplemental figures for "Mass-Balance Process Model of a Decoupled Aquaponics System"
Supplemental figures for "Mass-Balance Process Model of a Decoupled Aquaponics System" Open
Figure S1 shows water and feed inputs to the aquaponics system over the course of one year. Figure S2 shows modeled rates of nitrogen gas evolution over time due to denitrification in the aquaponics system.
View article: Supp. Table S2 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Supp. Table S2 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer Open
Supplementary Table S2: Somatic mutations
View article: Supp. Table S2 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Supp. Table S2 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer Open
Supplementary Table S2: Somatic mutations
View article: Supp. Table S21 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Supp. Table S21 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer Open
Supplementary Table S21: Segmented copy-number ratios
View article: Data from Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 <sup>c259</sup>T Cells in Synovial Sarcoma
Data from Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 <sup>c259</sup>T Cells in Synovial Sarcoma Open
We evaluated the safety and activity of autologous T cells expressing NY-ESO-1c259, an affinity-enhanced T-cell receptor (TCR) recognizing an HLA-A2–restricted NY-ESO-1/LAGE1a–derived peptide, in patients with metastatic synovial sarcoma (…
View article: Data from Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Data from Genetic Mechanisms of Immune Evasion in Colorectal Cancer Open
To understand the genetic drivers of immune recognition and evasion in colorectal cancer, we analyzed 1,211 colorectal cancer primary tumor samples, including 179 classified as microsatellite instability–high (MSI-high). This set includes …
View article: Supp. Table S22 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Supp. Table S22 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer Open
Supplementary Table S22: Segmented b-allele deficits
View article: Data from Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 <sup>c259</sup>T Cells in Synovial Sarcoma
Data from Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 <sup>c259</sup>T Cells in Synovial Sarcoma Open
We evaluated the safety and activity of autologous T cells expressing NY-ESO-1c259, an affinity-enhanced T-cell receptor (TCR) recognizing an HLA-A2–restricted NY-ESO-1/LAGE1a–derived peptide, in patients with metastatic synovial sarcoma (…
View article: Data from Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Data from Genetic Mechanisms of Immune Evasion in Colorectal Cancer Open
To understand the genetic drivers of immune recognition and evasion in colorectal cancer, we analyzed 1,211 colorectal cancer primary tumor samples, including 179 classified as microsatellite instability–high (MSI-high). This set includes …
View article: Supp. Tables S1, S3-S15, S20, and S23 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Supp. Tables S1, S3-S15, S20, and S23 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer Open
Supplementary Tables S1, S3 through S15, S20, and S23
View article: Figures S1-S7 from Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 <sup>c259</sup>T Cells in Synovial Sarcoma
Figures S1-S7 from Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 <sup>c259</sup>T Cells in Synovial Sarcoma Open
Figure S1. Consort diagram. Figure S2. Longitudinal analyses of persistence, memory cells and exhaustion marker expression. Figure S3. NY-ESO-1c259T cells exhibit and maintain polyfunctionality prior to and postinfusion. Figure S4. NY-ESO-…
View article: Supp. Table S22 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Supp. Table S22 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer Open
Supplementary Table S22: Segmented b-allele deficits
View article: Supp. Figures and Legends from Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Supp. Figures and Legends from Genetic Mechanisms of Immune Evasion in Colorectal Cancer Open
Supplementary Figures S1-S12 (with legends)
View article: Supp. Tables S16-S19 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Supp. Tables S16-S19 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer Open
Supplementary Tables S16-S19, describing IHC results on NHS/HPFS data
View article: Supp. Table S21 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Supp. Table S21 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer Open
Supplementary Table S21: Segmented copy-number ratios
View article: Figures S1-S7 from Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 <sup>c259</sup>T Cells in Synovial Sarcoma
Figures S1-S7 from Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 <sup>c259</sup>T Cells in Synovial Sarcoma Open
Figure S1. Consort diagram. Figure S2. Longitudinal analyses of persistence, memory cells and exhaustion marker expression. Figure S3. NY-ESO-1c259T cells exhibit and maintain polyfunctionality prior to and postinfusion. Figure S4. NY-ESO-…
View article: Supp. Figures and Legends from Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Supp. Figures and Legends from Genetic Mechanisms of Immune Evasion in Colorectal Cancer Open
Supplementary Figures S1-S12 (with legends)
View article: Supp. Tables S1, S3-S15, S20, and S23 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Supp. Tables S1, S3-S15, S20, and S23 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer Open
Supplementary Tables S1, S3 through S15, S20, and S23
View article: Supp. Tables S16-S19 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer
Supp. Tables S16-S19 from Genetic Mechanisms of Immune Evasion in Colorectal Cancer Open
Supplementary Tables S16-S19, describing IHC results on NHS/HPFS data
View article: Prior anti-CTLA-4 therapy impacts molecular characteristics associated with anti-PD-1 response in advanced melanoma
Prior anti-CTLA-4 therapy impacts molecular characteristics associated with anti-PD-1 response in advanced melanoma Open
Immune checkpoint inhibitors (ICIs), including CTLA-4- and PD-1-blocking antibodies, can have profound effects on tumor immune cell infiltration that have not been consistent in biopsy series reported to date. Here, we analyze seven molecu…
View article: Data from Circulating Tumor DNA Analysis to Assess Risk of Progression after Long-term Response to PD-(L)1 Blockade in NSCLC
Data from Circulating Tumor DNA Analysis to Assess Risk of Progression after Long-term Response to PD-(L)1 Blockade in NSCLC Open
Purpose:Treatment with PD-(L)1 blockade can produce remarkably durable responses in patients with non–small cell lung cancer (NSCLC). However, a significant fraction of long-term responders ultimately progress and predictors of late progre…
View article: Table S1 from Circulating Tumor DNA Analysis to Assess Risk of Progression after Long-term Response to PD-(L)1 Blockade in NSCLC
Table S1 from Circulating Tumor DNA Analysis to Assess Risk of Progression after Long-term Response to PD-(L)1 Blockade in NSCLC Open
Table S1 shows summary patient demographics, pathologic features, and treatment details
View article: Supplementary Table Legend from Tumor Characteristics Associated with Benefit from Pembrolizumab in Advanced Non–Small Cell Lung Cancer
Supplementary Table Legend from Tumor Characteristics Associated with Benefit from Pembrolizumab in Advanced Non–Small Cell Lung Cancer Open
Supplementary Table Legend
View article: Data from Tumor Characteristics Associated with Benefit from Pembrolizumab in Advanced Non–Small Cell Lung Cancer
Data from Tumor Characteristics Associated with Benefit from Pembrolizumab in Advanced Non–Small Cell Lung Cancer Open
Purpose:Several biomarkers have been individually associated with response to PD-1 blockade, including PD-L1 and tumor mutational burden (TMB) in non–small cell lung cancer (NSCLC), and CD8 cells in melanoma. We sought to examine the relat…
View article: Supplementary Tables S2-S7 from Circulating Tumor DNA Analysis to Assess Risk of Progression after Long-term Response to PD-(L)1 Blockade in NSCLC
Supplementary Tables S2-S7 from Circulating Tumor DNA Analysis to Assess Risk of Progression after Long-term Response to PD-(L)1 Blockade in NSCLC Open
Table S2: Surveillance plasma sample ctDNA metrics. Table S3: Baseline plasma sample ctDNA metrics. Table S4: Surveillance plasma sample variants in ctDNA detected samples. Table S5: Baseline plasma variants in available samples. Table S6:…
View article: Table S1 from Circulating Tumor DNA Analysis to Assess Risk of Progression after Long-term Response to PD-(L)1 Blockade in NSCLC
Table S1 from Circulating Tumor DNA Analysis to Assess Risk of Progression after Long-term Response to PD-(L)1 Blockade in NSCLC Open
Table S1 shows summary patient demographics, pathologic features, and treatment details