Daniel Youkee
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View article: Estimating annual deaths from stroke in adults under 70 years of age in Freetown Sierra Leone: A comparative analysis of a hospital-based stroke register and a population-based verbal autopsy study
Estimating annual deaths from stroke in adults under 70 years of age in Freetown Sierra Leone: A comparative analysis of a hospital-based stroke register and a population-based verbal autopsy study Open
Background: In Sub-Saharan Africa (SSA), most stroke epidemiological data comes from hospital-based registers, which are prone to selection bias, and data may be unrepresentative of stroke burden at the population level. The degree of inco…
View article: Effect of the COVID-19 pandemic on the post-Ebola referral system in Sierra Leone: A descriptive analysis
Effect of the COVID-19 pandemic on the post-Ebola referral system in Sierra Leone: A descriptive analysis Open
Background The COVID-19 pandemic severely impacted health systems in several countries, including Sierra Leone, which was recovering from the 2014-2016 Ebola Virus Disease epidemic. The National Referral Service was established in 2017 fol…
View article: Developing a strategic action plan for reducing the burden of stroke in Africa: report of the first African Stroke Leaders' Summit
Developing a strategic action plan for reducing the burden of stroke in Africa: report of the first African Stroke Leaders' Summit Open
Introduction Stroke is a leading cause of adult neurologic disability, cognitive decline, and death worldwide, and particularly in Africa. Stroke research in Africa has exposed challenges militating against the translation of research evid…
View article: Socioeconomic Status and Stroke: A Review of the Latest Evidence on Inequalities and Their Drivers
Socioeconomic Status and Stroke: A Review of the Latest Evidence on Inequalities and Their Drivers Open
The latest research on socioeconomic status (SES) and stroke continues to demonstrate that individuals with low SES are at a higher risk of stroke, receive lower-quality care, and experience poorer outcomes. Despite growing evidence on the…
View article: The effect of the COVID-19 pandemic on emergency maternal and under-five referrals in Sierra Leone: A cohort study
The effect of the COVID-19 pandemic on emergency maternal and under-five referrals in Sierra Leone: A cohort study Open
Background In Sierra Leone, the National Emergency Medical Services (NEMS) was designed to facilitate maternal and under-five referrals. During the COVID-19 pandemic, health facilities were repurposed and mobility restrictions were introdu…
View article: A scoping review of stroke registers in Sub-Saharan Africa
A scoping review of stroke registers in Sub-Saharan Africa Open
Background: Stroke registers are recommended as a key priority by the Lancet Neurology World Stroke Organization Commission for Stroke, 2023, and the African Stroke Leaders’ Summit, 2022. Aims: This scoping review aims to map where stroke …
View article: Quality of life and quality-adjusted life years after stroke in Sierra Leone
Quality of life and quality-adjusted life years after stroke in Sierra Leone Open
Background: Stroke is a leading cause of mortality and negatively affects health-related quality of life (HRQoL). HRQoL after stroke is understudied in Africa and there are no reports of quality-adjusted life years after stroke (QALYs) in …
View article: The feasibility, repeatability, validity and responsiveness of the EQ-5D-3L in Krio for patients with stroke in Sierra Leone
The feasibility, repeatability, validity and responsiveness of the EQ-5D-3L in Krio for patients with stroke in Sierra Leone Open
Objectives To assess the feasibility, repeatability, validity and responsiveness of the EQ-5D-3L in Krio for patients with stroke in Sierra Leone, the first psychometric assessment of the EQ-5D-3L to be conducted in patients with stroke in…
View article: A qualitative study examining the health system’s response to COVID-19 in Sierra Leone
A qualitative study examining the health system’s response to COVID-19 in Sierra Leone Open
The paper examines the health system’s response to COVID-19 in Sierra Leone. It aims to explore how the pandemic affected service delivery, health workers, patient access to services, leadership, and governance. It also examines to what ex…
View article: Improving the quality of COVID-19 care in Sierra Leone: A modified Delphi process and serial nationwide assessments of quality of COVID-19 care in Sierra Leone
Improving the quality of COVID-19 care in Sierra Leone: A modified Delphi process and serial nationwide assessments of quality of COVID-19 care in Sierra Leone Open
Introduction Improving the quality of care that patients receive is paramount to improving patient outcomes and engendering trust during infectious disease outbreaks. Whilst Quality Improvement (QI) is well established to drive improvement…
View article: Cohort Profile: The Stroke in Sierra Leone (SISLE) Register
Cohort Profile: The Stroke in Sierra Leone (SISLE) Register Open
Why was the cohort set up?Stroke is the second leading cause of death in Sub-Saharan Africa (SSA), 1 with evidence suggesting that incidence is increasing over time. 2 However, epidemiological studies of stroke in SSA are limited in number…
View article: Stroke in Sierra Leone. the stroke risk factors for people with HIV: A prospective case-control study
Stroke in Sierra Leone. the stroke risk factors for people with HIV: A prospective case-control study Open
These findings support the current call for timely management of stroke and HIV through integrated care.
View article: Stroke in Sierra Leone: Case fatality rate and functional outcome after stroke in Freetown
Stroke in Sierra Leone: Case fatality rate and functional outcome after stroke in Freetown Open
Background: There is limited information on long-term outcomes after stroke in sub-Saharan Africa (SSA). Current estimates of case fatality rate (CFR) in SSA are based on small sample sizes with varying study design and report heterogeneou…
View article: All-cause mortality of hospitalised patients with suspected COVID-19 in Sierra Leone: a prospective cohort study
All-cause mortality of hospitalised patients with suspected COVID-19 in Sierra Leone: a prospective cohort study Open
Objectives To study the mortality of patients with COVID-19 in Sierra Leone, to explore the factors associated with mortality during the COVID-19 pandemic and to highlight the complexities of treating patients with a novel epidemic disease…
View article: Effects of therapies for Ebola virus disease: a systematic review and network meta-analysis
Effects of therapies for Ebola virus disease: a systematic review and network meta-analysis Open
View article: Exploring the experiences of stroke survivors, informal caregivers and healthcare providers in Sierra Leone: a qualitative study protocol
Exploring the experiences of stroke survivors, informal caregivers and healthcare providers in Sierra Leone: a qualitative study protocol Open
Introduction Stroke is now the second leading cause of adult death in Sub-Saharan Africa. Developed in dialogue with stroke survivors and caregivers in Sierra Leone, this will be the first study to explore the experience of stroke as well …
View article: Association between ambulance prehospital time and maternal and perinatal outcomes in Sierra Leone: a countrywide study
Association between ambulance prehospital time and maternal and perinatal outcomes in Sierra Leone: a countrywide study Open
Introduction Sierra Leone, one of the countries with the highest maternal and perinatal mortality in the world, launched its first National Emergency Medical Service (NEMS) in 2018. We carried out a countrywide assessment to analyse NEMS o…
View article: The impact of the COVID-19 pandemic on hospital utilisation in Sierra Leone
The impact of the COVID-19 pandemic on hospital utilisation in Sierra Leone Open
Introduction The COVID-19 pandemic has adversely affected health systems in many countries, but little is known about effects on health systems in sub-Saharan Africa. This study examines the effects of COVID-19 on hospital utilisation in a…
View article: Improving Access to Healthcare in Sierra Leone: The Role of the Newly Developed National Emergency Medical Service
Improving Access to Healthcare in Sierra Leone: The Role of the Newly Developed National Emergency Medical Service Open
We aim to evaluate whether the first National Emergency Medical Service (NEMS) improved access to hospital care for the people of Sierra Leone. We performed an interrupted time-series analysis to assess the effects of NEMS implementation o…
View article: A Prospective Stroke Register in Sierra Leone: Demographics, Stroke Type, Stroke Care and Hospital Outcomes
A Prospective Stroke Register in Sierra Leone: Demographics, Stroke Type, Stroke Care and Hospital Outcomes Open
Introduction: Stroke is the second most common cause of adult death in Africa. This study reports the demographics, stroke types, stroke care and hospital outcomes for stroke in Freetown, Sierra Leone. Methods: A prospective observational …
View article: The impact of the COVID-19 pandemic on health service utilisation in Sierra Leone
The impact of the COVID-19 pandemic on health service utilisation in Sierra Leone Open
Introduction The COVID-19 pandemic has adversely affected health systems in many countries, but little is known about effects on health systems in sub-Saharan Africa. This study examines the effects of COVID-19 on health service utilisatio…
View article: An Observational Study of a National Referral System: An Analysis of 14,266 Referrals in Sierra Leone
An Observational Study of a National Referral System: An Analysis of 14,266 Referrals in Sierra Leone Open
Background Referral systems are critical to a well-functioning health system. In 2017, a special cadre of referral coordinators were trained and deployed at every district and tertiary hospital in Sierra Leone. We analyse the referrals coo…
View article: Development of a Pediatric Ebola Predictive Score, Sierra Leone1
Development of a Pediatric Ebola Predictive Score, Sierra Leone1 Open
We compared children who were positive for Ebola virus disease (EVD) with those who were negative to derive a pediatric EVD predictor (PEP) score. We collected data on all children <13 years of age admitted to 11 Ebola holding units in Sie…
View article: Novel surveillance methods for the control of Ebola virus disease
Novel surveillance methods for the control of Ebola virus disease Open
The unprecedented scale of the 2013-2016 West African Ebola virus disease (EVD) outbreak was in a large part due to failings in surveillance: contacts of confirmed cases were not systematically identified, monitored and diagnosed early, an…
View article: Risk in the “Red Zone”: Outcomes for Children Admitted to Ebola Holding Units in Sierra Leone Without Ebola Virus Disease
Risk in the “Red Zone”: Outcomes for Children Admitted to Ebola Holding Units in Sierra Leone Without Ebola Virus Disease Open
We collected data on 1054 children admitted to Ebola Holding Units in Sierra Leone and describe outcomes of 697/1054 children testing negative for Ebola virus disease (EVD) and accompanying caregivers. Case-fatality was 9%; 3/630 (0.5%) ch…
View article: Refining the paediatric Ebola case definition: a study of children in Sierra Leone with suspected Ebola virus disease
Refining the paediatric Ebola case definition: a study of children in Sierra Leone with suspected Ebola virus disease Open
View article: Management of Ebola virus disease: is environmental decontamination effective?
Management of Ebola virus disease: is environmental decontamination effective? Open
View article: Quantifying the risk of nosocomial infection within Ebola Holding Units: a retrospective cohort study of negative patients discharged from five Ebola Holding Units in Western Area, Sierra Leone
Quantifying the risk of nosocomial infection within Ebola Holding Units: a retrospective cohort study of negative patients discharged from five Ebola Holding Units in Western Area, Sierra Leone Open
Objectives A central pillar in the response to the 2014 Ebola virus disease ( EVD ) epidemic in Sierra Leone was the role of Ebola Holding Units ( EHU s). These units isolated patients meeting a suspect case definition, tested them for EVD…
View article: Ebola Virus Disease in Children, Sierra Leone, 2014–2015
Ebola Virus Disease in Children, Sierra Leone, 2014–2015 Open
Little is known about potentially modifiable factors in Ebola virus disease in children. We undertook a retrospective cohort study of children <13 years old admitted to 11 Ebola holding units in the Western Area, Sierra Leone, during 2014-…
View article: Ebola Virus Disease in Children, Sierra Leone, 2014–2015
Ebola Virus Disease in Children, Sierra Leone, 2014–2015 Open
Little is known about potentially modifiable factors in Ebola virus disease in children. We undertook a retrospective cohort study of children <13 years old admitted to 11 Ebola holding units in the Western Area, Sierra Leone, during 2014–…