Daniela Ciobanu
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View article: The Interplay of Cardiometabolic Syndrome Phenotypes and Cardiovascular Risk Indices in Patients Diagnosed with Diabetes Mellitus
The Interplay of Cardiometabolic Syndrome Phenotypes and Cardiovascular Risk Indices in Patients Diagnosed with Diabetes Mellitus Open
Metabolic syndrome (MetS) and its associated cardiometabolic phenotypes significantly contribute to the global burden of cardiovascular disease (CVD), especially in individuals with type 2 diabetes mellitus (T2DM) and prediabetes. This stu…
View article: Pediatric inflammatory multisystem syndrome or Kawasaki disease - continuous challenges in Pediatrics - case report
Pediatric inflammatory multisystem syndrome or Kawasaki disease - continuous challenges in Pediatrics - case report Open
Introduction. Kawasaki disease (KD) and pediatric inflammatory multisystem syndrome (PIMS) are similar vasculitis conditions affecting medium and small vessels, particularly the coronary arteries. This study aimed to highlight diagnostic a…
View article: Epidemiological and Clinical Aspects in a Cohort of Colorectal Cancer Patients.
Epidemiological and Clinical Aspects in a Cohort of Colorectal Cancer Patients. Open
We conducted a retrospective, observational study, based on 91 patients diagnosed with colorectal cancer (CRC), hospitalized and evaluated within the Surgical and the 2nd Internal Medicine Clinic, the Clinical Emergency County Hospital Cra…
View article: Clinical-epidemiological aspects in a cohort of ankylosing spondylitis patients
Clinical-epidemiological aspects in a cohort of ankylosing spondylitis patients Open
View article: IL-17, IL-23 and disease activity in a cohort of ankylosing spondylitis patients
IL-17, IL-23 and disease activity in a cohort of ankylosing spondylitis patients Open
View article: Molecular prognostic factors in colorectal cancer: 5-year follow-up
Molecular prognostic factors in colorectal cancer: 5-year follow-up Open
Colorectal cancer (CRC) is a frequently diagnosed and lethal disease. The risk of developing CRC is determined by environmental and genetic factors. Surgical treatment is the main curative modality for patients with CRC up to stage III. In…
View article: Immunoexpression of Mismatch Repair Proteins in a Cohort of Colorectal Cancer Patients.
Immunoexpression of Mismatch Repair Proteins in a Cohort of Colorectal Cancer Patients. Open
One of the molecular routes of colorectal carcinogenesis is the lack of mismatch repair (MMR) proteins, which may have substantial clinical consequences in predicting therapy success. This study aimed to analyze the expression of the MutL …
View article: Circulating MicroRNAs and Extracellular Vesicle-Derived MicroRNAs as Predictors of Functional Recovery in Ischemic Stroke Patients: A Systematic Review and Meta-Analysis
Circulating MicroRNAs and Extracellular Vesicle-Derived MicroRNAs as Predictors of Functional Recovery in Ischemic Stroke Patients: A Systematic Review and Meta-Analysis Open
Stroke accounts for the second leading cause of death and a major cause of disability, with limited therapeutic strategy in both the acute and chronic phases. Blood-based biomarkers are intensively researched and widely recognized as usefu…
View article: Chronic Calcifying Pancreatitis Associated with Secondary Diabetes Mellitus and Hepatosplenic Abscesses in a Young Male Patient: A Case Report
Chronic Calcifying Pancreatitis Associated with Secondary Diabetes Mellitus and Hepatosplenic Abscesses in a Young Male Patient: A Case Report Open
Background: Chronic pancreatitis (CP) has been described as a multifactorial, ongoing inflammatory condition of the pancreas of varying intensity that produces persistent pain, leading to exocrine and endocrine insufficiency and a decrease…
View article: Biological markers of inflammatory response and coagulopathy in COVID-19 are related with an increased risk of severe disease and death
Biological markers of inflammatory response and coagulopathy in COVID-19 are related with an increased risk of severe disease and death Open
View article: Introducerea plantelor din genul Sansevieria Thunb. în Grădina Botanică Naţională (Institut) „Al. Ciubotaru”
Introducerea plantelor din genul Sansevieria Thunb. în Grădina Botanică Naţională (Institut) „Al. Ciubotaru” Open
The genus Sansevieria is very diverse and interesting in terms of life forms and shapes and enjoys great popularity among both botanists and plant lovers, who in recent years have become increasingly interested in these plants due to their…
View article: Celiac crisis, atypical form of celiac disease onset in teenager – a case report
Celiac crisis, atypical form of celiac disease onset in teenager – a case report Open
Celiac disease (CD) is an immune mediated disorder triggered by gluten diet genetically susceptible individuals. Celiac crisis is a rare but potentially lethal condition that can occur in a previously known celiac disease or as its first m…
View article: Criza celiacă, formă atipică de debut al bolii celiace la adolescent – prezentare de caz
Criza celiacă, formă atipică de debut al bolii celiace la adolescent – prezentare de caz Open
Boala celiacă (BC) este o afecțiune sistemică mediată imun determinată de dieta cu gluten la indivizii susceptibili genetic. Criza celiacă este o afecțiune rară, dar cu potențial letal, care poate apărea în cadrul bolii celiace sau ca prim…
View article: Hepatitis A, a potential life-threatening condition in small children with Wilson disease – a case report
Hepatitis A, a potential life-threatening condition in small children with Wilson disease – a case report Open
Introduction. Hepatitis A is the most common cause of acute hepatitis in children. Wilson disease (WD) is a rare autosomal recessive condition that can result in chronic liver disease. Hepatitis A may be a trigger in the onset of WD. Case …
View article: Hepatita A, o patologie amenințătoare de viață la copiii mici cu boală Wilson – prezentare de caz
Hepatita A, o patologie amenințătoare de viață la copiii mici cu boală Wilson – prezentare de caz Open
Introducere. Hepatita A este cea mai frecventă cauză de hepatită acută la copii. Boala Wilson (BW) este o patologie autozomal recesivă rară care poate duce la hepatopatie cronică. Hepatita A poate reprezenta un trigger pentru debutul BW. P…
View article: Demographic, anthropometric and laboratory characteristics in obese children
Demographic, anthropometric and laboratory characteristics in obese children Open
Introduction. The incidence of obesity reached alarming rated in pediatric population resulting in a global public health problem. The aim of our study consists of the assessment of anthropometric and laboratory parameters in obese childre…
View article: Caracteristici demografice, antropometrice şi de laborator la copiii obezi
Caracteristici demografice, antropometrice şi de laborator la copiii obezi Open
Introducere. Incidenţa obezităţii a crescut alarmant la populaţia pediatrică, ajungând să reprezinte o problemă de sănătate publică globală. Scopul studiului nostru constă în evaluarea parametrilor antropometrici şi de laborator la copiii …
View article: Portraits: Petru Derevenco - the man and his work
Portraits: Petru Derevenco - the man and his work Open
View article: P832 ESCAPE Stroke: first results
P832 ESCAPE Stroke: first results Open
Objective "ESCAPE Stroke" (Enhancement, Segmentation and Characterization of Atheroma PlaquE for Stroke Prevention) is a multidisciplinary project that aims to develop a new software tool to obtain maximum information about carotid atheros…
View article: Raspunsul gazdei la hepatita cronica virala B
Raspunsul gazdei la hepatita cronica virala B Open
This review discusses and tries to demonstrate the importance of proinflammatory and antiinflammatory cytokines in HBV infection. Hepatitis B virus is a virus that is both hepatotropic and non-cytopathic. It causes the development of liver…
View article: Benefit of Cardiac Resynchronization Therapy in Patients with Heart Failure
Benefit of Cardiac Resynchronization Therapy in Patients with Heart Failure Open
Heart failure is a disease characterized by cardiac remodeling or progressive dilation of left ventricle and a consequent reduction in contraction. Ventricular remodeling has been shown to be a negative prognostic factor alone, and therefo…
View article: Determination of Antioxidant Components and Activity of Tamarix ramosissima Comparative with Vaccinium myrtillus on Streptozotocin-diabetic Mice
Determination of Antioxidant Components and Activity of Tamarix ramosissima Comparative with Vaccinium myrtillus on Streptozotocin-diabetic Mice Open
Tamarix ramosissima (Tamaricaceae) is a small tree that grows spontaneously in Europe and Asia, being considered an invasive species in geographical areas with warm climates. The chemical composition is partially elucidated, being empirica…
View article: Determination of the Inhibitory Capacity on HMG-CoA Reductase Enzyme by Statins Using Molecular Docking Method
Determination of the Inhibitory Capacity on HMG-CoA Reductase Enzyme by Statins Using Molecular Docking Method Open
Statins are a class of lipid-lowering medications that reduce cardiovascular disease and mortality in pacients who are at high risk. The molecular docking technique has become an increasingly important tool for drug discovery which help us…
View article: Immunohistochemical Expression of CD8, CDX2, P53, D2-40 and KI 67 in Colorectal Adenocarcinoma, Conventional and Malignant Colo-rectal Polyps
Immunohistochemical Expression of CD8, CDX2, P53, D2-40 and KI 67 in Colorectal Adenocarcinoma, Conventional and Malignant Colo-rectal Polyps Open
82 patients, who had been diagnosed with colo-rectal adenocarcinoma in our department between 2007 and 2014, were included in our study. Additionally, 31 patients with colo-rectal polyps (20 conventional adenomatous polyps and 11 malignant…
View article: Ischemic colitis problems of diagnosis and treatment
Ischemic colitis problems of diagnosis and treatment Open
Objective: The aim of the study is to evaluate the characteristics of colonic ischemia and to identfy clinicobiological factors. Methods We performed a retrospective study of 20 patients in whom the diagnosis was made intraoperatively and …
View article: LOS Colon Cancer 621 cases
LOS Colon Cancer 621 cases Open
The data set comes from the University of Medicine and Pharmacy of Craiova, Romania, and concerns the hospitalization period of 621 patients diagnosed with colorectal cancer that underwent surgery between 2007 and 2014. It contains 8 attri…
View article: Length of Stay Colon Cancer
Length of Stay Colon Cancer Open
The data set comes from the University of Medicine and Pharmacy of Craiova, Romania, and concerns the hospitalization period of 368 patients diagnosed with colorectal cancer that underwent surgery between 2012 and 2014. It contains 8 attri…
View article: Colorectal cancer histopathological image data set
Colorectal cancer histopathological image data set Open
The data set has 357 histopathological images of normal tissue and for cancer grades G1, G2, and G3, with the 10x magnification level. They have a similar resolution of 800x600 pixels and are distributed as follows: 62 cases as normal, 96 …
View article: Study of the Etiological Spectrum of Spontaneous Bacterial Peritonitis in a Group of Patients Suffering from Liver Cirrhosis.
Study of the Etiological Spectrum of Spontaneous Bacterial Peritonitis in a Group of Patients Suffering from Liver Cirrhosis. Open
Spontaneous bacterial peritonitis (SBP) represents the most severe and common infectious complication in patients suffering from liver cirrhosis. The objectives of the study were the evaluation of the risk factors responsible for the occur…
View article: Cytopathological Aspects in the Bronchoalveolar Lavage Fluid in Chronic Obstructive Pulmonary Disease.
Cytopathological Aspects in the Bronchoalveolar Lavage Fluid in Chronic Obstructive Pulmonary Disease. Open
Chronic Obstructive Pulmonary Disease (COPD) is a clinical syndrome characterised by a slow progressive decline in expiratory airflow [1], a process that has gradually developed over the years. Studies of patients with COPD show an inflamm…