Daniela Hacker
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View article: The Molecular Architecture of Somatic Spines of the Lateral Septum
The Molecular Architecture of Somatic Spines of the Lateral Septum Open
The lateral septum is a key subcortical structure and has been implicated in kinship memory. Across species, the ability to recognise relatives is conserved and is reflected in stable, lifelong memories. The molecular mechanisms underlying…
View article: Unveiling the cell biology of hippocampal neurons with dendritic axon origin
Unveiling the cell biology of hippocampal neurons with dendritic axon origin Open
In mammalian axon-carrying–dendrite (AcD) neurons, the axon emanates from a basal dendrite, instead of the soma, to create a privileged route for action potential generation at the axon initial segment (AIS). However, it is unclear how suc…
View article: Functional interdependence of the actin regulators CAP1 and cofilin1 in control of dendritic spine morphology
Functional interdependence of the actin regulators CAP1 and cofilin1 in control of dendritic spine morphology Open
The vast majority of excitatory synapses are formed on small dendritic protrusions termed dendritic spines. Dendritic spines vary in size and density that are crucial determinants of excitatory synaptic transmission. Aberrations in spine m…
View article: Functional interdependence of the actin regulators CAP1 and cofilin1 in control of dendritic spine morphology
Functional interdependence of the actin regulators CAP1 and cofilin1 in control of dendritic spine morphology Open
The vast majority of excitatory synapses are formed on small dendritic protrusions termed dendritic spines. Dendritic spines vary in size and density that are both crucial determinants of excitatory synaptic transmission. Aberrations in sp…
View article: Control of synaptic vesicle release probability via VAMP4 targeting to endolysosomes
Control of synaptic vesicle release probability via VAMP4 targeting to endolysosomes Open
VAMP4 is a molecular rheostat that adjusts neurotransmitter release to both the activity and degradative status of neurons.