Daniela Predoi
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View article: Development and Physico-Chemical and Antibacterial Characterization of Chromium-Doped Hydroxyapatite in a Chitosan Matrix Coating
Development and Physico-Chemical and Antibacterial Characterization of Chromium-Doped Hydroxyapatite in a Chitosan Matrix Coating Open
Chromium-doped hydroxyapatite (7CrHAp) and chromium-doped hydroxyapatite in chitosan matrix (7CrHAp-CH) coatings were synthesized in order to address the need for biomaterials with improved physico-chemical and biological properties for bi…
View article: Physicochemical and Preliminary Biological Properties of Thin Films Based on Fluoride-Doped Hydroxyapatite in a Dextran Matrix for Biomedical Applications
Physicochemical and Preliminary Biological Properties of Thin Films Based on Fluoride-Doped Hydroxyapatite in a Dextran Matrix for Biomedical Applications Open
A spin-coating technique was used to produce new thin films of fluoride-doped hydroxyapatite (HApF) and fluoride-doped hydroxyapatite in a dextran matrix (HApF-Dx) with the potential to be used as nanocoatings for various biomedical implan…
View article: Development of Chrome-Doped Hydroxyapatite in a PVA Matrix Enriched with Amoxicillin for Biomedical Applications
Development of Chrome-Doped Hydroxyapatite in a PVA Matrix Enriched with Amoxicillin for Biomedical Applications Open
Background/Objectives: In this paper, we report the development of the first chrome-doped hydroxyapatite in a poly (vinyl alcohol) (PVA) matrix enriched with amoxicillin for biomedical applications. The development of chromium-doped hydrox…
View article: Influence of Electron Beam Irradiation and RPMI Immersion on the Development of Magnesium-Doped Hydroxyapatite/Chitosan Composite Bioactive Layers for Biomedical Applications
Influence of Electron Beam Irradiation and RPMI Immersion on the Development of Magnesium-Doped Hydroxyapatite/Chitosan Composite Bioactive Layers for Biomedical Applications Open
Magnesium-doped hydroxyapatite/chitosan composite coatings produced by the radio-frequency magnetron sputtering technique were exposed to 5 MeV electron beams of 8 and 30 Gy radiation doses in a linear electron accelerator. The surfaces of…
View article: Chrome Doped Hydroxyapatite Enriched with Amoxicillin Layers for Biomedical Applications
Chrome Doped Hydroxyapatite Enriched with Amoxicillin Layers for Biomedical Applications Open
In the last decade, it has been observed that the field of biomaterials has gained the attention of the researchers. This study presents the physicochemical and biological properties of coatings based on chromium-doped hydroxyapatite (CrHA…
View article: Exploring the Effects of Dulbecco’s Modified Eagle’s Medium on Irradiated Layers of Magnesium-Doped Hydroxyapatite in a Chitosan Matrix for Biomedical Applications
Exploring the Effects of Dulbecco’s Modified Eagle’s Medium on Irradiated Layers of Magnesium-Doped Hydroxyapatite in a Chitosan Matrix for Biomedical Applications Open
In this paper, we present the development of magnesium-doped hydroxyapatite in chitosan matrix (MHA_Ch) powder by an adapted coprecipitation method. The MHA_Ch powder was then deposited as thin layers by radio frequency magnetron sputterin…
View article: New Nanobioceramics Based on Hydroxyapatite for Biomedical Applications: Stability and Properties
New Nanobioceramics Based on Hydroxyapatite for Biomedical Applications: Stability and Properties Open
In this work, we report for the first time the development and complex characterization of new bioceramics based on hydroxyapatite (HAp, Ca10(PO4)6(OH)2). On the other hand, the lyophilization process was used for the first time in this re…
View article: Exploring the fabrication, properties, and morphology of fluorine substituted hydroxyapatite coatings
Exploring the fabrication, properties, and morphology of fluorine substituted hydroxyapatite coatings Open
View article: Development of Novel Biocomposites with Antimicrobial-Activity-Based Magnesium-Doped Hydroxyapatite with Amoxicillin
Development of Novel Biocomposites with Antimicrobial-Activity-Based Magnesium-Doped Hydroxyapatite with Amoxicillin Open
Background/Objectives: A biocomposite based on magnesium-doped hydroxyapatite and enriched with amoxicillin (MgHApOx) was synthesized using the coprecipitation method and is presented here for the first time. Methods: The stability of MgHA…
View article: Novel Antimicrobial Agents Based on Zinc-Doped Hydroxyapatite Loaded with Tetracycline
Novel Antimicrobial Agents Based on Zinc-Doped Hydroxyapatite Loaded with Tetracycline Open
In this paper, we present for the first time the development of zinc-doped hydroxyapatite enriched with tetracycline (ZnHApTe) powders and provide a comprehensive evaluation of their physico-chemical and biological properties. Various tech…
View article: Development and Characterization of Silver Doped Hydroxyapatite/Chitosan Nanobiocomposites
Development and Characterization of Silver Doped Hydroxyapatite/Chitosan Nanobiocomposites Open
The aim of this study is to develop a new nanobiocomposite based on silver doped hydroxyapatite (AgHAp)/chitosan (CH), AgHAp‐CH ( x Ag = 0.15) by an adapted method. The obtained nanobiocomposites are studied by scanning electron microscopy…
View article: Influence of Synthesis Method and Electrode Geometry on GHG-Sensing Properties of 5%Gd-Doped SnO2
Influence of Synthesis Method and Electrode Geometry on GHG-Sensing Properties of 5%Gd-Doped SnO2 Open
This study investigates the influence of synthesis methods and electrode geometry on the physico-chemical properties of 5%Gd-doped SnO2. Two distinct synthesis routes, co-precipitation and hydrothermal growth, were employed, resulting in p…
View article: Physico‐Chemical and Antimicrobial Features of Magnesium Doped Hydroxyapatite Nanoparticles in Polymer Matrix
Physico‐Chemical and Antimicrobial Features of Magnesium Doped Hydroxyapatite Nanoparticles in Polymer Matrix Open
Magnesium doped hydroxyapatite nanoparticles in dextran matrix (7MgHApDx) with average size diameter of 18.2 ± 0.5 nm are synthesized by co‐precipitation. The surface morphology and shape of 7MgHApDx particles are established by scanning e…
View article: Copper doped hydroxyapatite nanocomposite thin films: synthesis, physico–chemical and biological evaluation
Copper doped hydroxyapatite nanocomposite thin films: synthesis, physico–chemical and biological evaluation Open
View article: Physico-Chemical Properties of Copper-Doped Hydroxyapatite Coatings Obtained by Vacuum Deposition Technique
Physico-Chemical Properties of Copper-Doped Hydroxyapatite Coatings Obtained by Vacuum Deposition Technique Open
The hydroxyapatite and copper-doped hydroxyapatite coatings (Ca10−xCux(PO4)6(OH)2; xCu = 0, 0.03; HAp and 3CuHAp) were obtained by the vacuum deposition technique. Then, both coatings were analyzed by the X-ray diffraction (XRD), scanning …
View article: Physico-Chemical and Biological Features of Fluorine-Substituted Hydroxyapatite Suspensions
Physico-Chemical and Biological Features of Fluorine-Substituted Hydroxyapatite Suspensions Open
Infections related to orthopedic/stomatology surgery are widely recognized as a significant health concern. Therefore, the development of new materials with superior biological properties and good stability could represent a valuable alter…
View article: Biocompatibility and Osteogenic Activity of Samarium-Doped Hydroxyapatite—Biomimetic Nanoceramics for Bone Regeneration Applications
Biocompatibility and Osteogenic Activity of Samarium-Doped Hydroxyapatite—Biomimetic Nanoceramics for Bone Regeneration Applications Open
In this study, we report on the development of hydroxyapatite (HAp) and samarium-doped hydroxyapatite (SmHAp) nanoparticles using a cost-effective method and their biological effects on a bone-derived cell line MC3T3-E1. The physicochemica…
View article: Development of Dextran Coated Zinc Oxide Nanoparticles with Antimicrobial Properties
Development of Dextran Coated Zinc Oxide Nanoparticles with Antimicrobial Properties Open
Dextran coated zinc oxide nanoparticles with various zinc concentration have been developed in this study. Various characterization techniques were used in order to study the physical-chemical properties of the obtained samples. The struct…
View article: Influence of the Synthesis Method on the Material Characteristics and Ghg-Sensing Properties of 5%Gd-Doped Sno2
Influence of the Synthesis Method on the Material Characteristics and Ghg-Sensing Properties of 5%Gd-Doped Sno2 Open
View article: New Physico-Chemical Analysis of Magnesium-Doped Hydroxyapatite in Dextran Matrix Nanocomposites
New Physico-Chemical Analysis of Magnesium-Doped Hydroxyapatite in Dextran Matrix Nanocomposites Open
The new magnesium-doped hydroxyapatite in dextran matrix (10MgHApD) nanocomposites were synthesized using coprecipitation technique. A spherical morphology was observed by scanning electron microscopy (SEM). The X-ray diffraction (XRD) cha…
View article: Salvia officinalis–Hydroxyapatite Nanocomposites with Antibacterial Properties
Salvia officinalis–Hydroxyapatite Nanocomposites with Antibacterial Properties Open
In the present study, sage-coated zinc-doped hydroxyapatite was incorporated into a dextran matrix (7ZnHAp-SD), and its physico-chemical and antimicrobial activities were investigated. A 7ZnHAp-SD nanocomposite suspension was obtained usin…
View article: Complex Evaluation of Nanocomposite-Based Hydroxyapatite for Biomedical Applications
Complex Evaluation of Nanocomposite-Based Hydroxyapatite for Biomedical Applications Open
A magnesium-doped hydroxyapatite in chitosan matrix (MgHApC) sample was developed as a potential platform for numerous applications in the pharmaceutical, medical, and food industries. Magnesium-doped hydroxyapatite suspensions in the chit…
View article: Sodium bicarbonate-hydroxyapatite used for removal of lead ions from aqueous solution
Sodium bicarbonate-hydroxyapatite used for removal of lead ions from aqueous solution Open
View article: Biocomposite Coatings Doped with Magnesium and Zinc Ions in Chitosan Matrix for Antimicrobial Applications
Biocomposite Coatings Doped with Magnesium and Zinc Ions in Chitosan Matrix for Antimicrobial Applications Open
Hydroxyapatite doped with magnesium and zinc in chitosan matrix biocomposites have great potential for applications in space technology, aerospace, as well as in the biomedical field, as a result of coatings with multifunctional properties…
View article: Dextran-Coated Iron Oxide Nanoparticles Loaded with 5-Fluorouracil for Drug-Delivery Applications
Dextran-Coated Iron Oxide Nanoparticles Loaded with 5-Fluorouracil for Drug-Delivery Applications Open
This study aims to design and test different formulations composed of dextran-coated iron oxide nanoparticles (IONPs) loaded with 5-Fluorouracil (5-FU) with varying nanoparticle:drug ratios on colorectal cancer cells. The stable suspension…
View article: Biological Response of Human Gingival Fibroblasts to Zinc-Doped Hydroxyapatite Designed for Dental Applications—An In Vitro Study
Biological Response of Human Gingival Fibroblasts to Zinc-Doped Hydroxyapatite Designed for Dental Applications—An In Vitro Study Open
This study aimed to investigate the biological response induced by hydroxyapatite (HAp) and zinc-doped HAp (ZnHAp) in human gingival fibroblasts and to explore their antimicrobial activity. The ZnHAp (with xZn = 0.00 and 0.07) powders, syn…
View article: Studies of the Tarragon Essential Oil Effects on the Characteristics of Doped Hydroxyapatite/Chitosan Biocomposites
Studies of the Tarragon Essential Oil Effects on the Characteristics of Doped Hydroxyapatite/Chitosan Biocomposites Open
Due to the emergence of antibiotic-resistant pathogens, the need to find new, efficient antimicrobial agents is rapidly increasing. Therefore, in this study, we report the development of new biocomposites based on zinc-doped hydroxyapatite…
View article: Studies of New Layer Formation on the Surface of Zinc Doped Hydroxyapatite/Chitosan Composite Coatings in Biological Medium
Studies of New Layer Formation on the Surface of Zinc Doped Hydroxyapatite/Chitosan Composite Coatings in Biological Medium Open
Usually, before being used in biomedical applications, a biomaterials’ bioactivity is tested by in vitro methods that simulate similar conditions to those found in the human body. In this work, we report on the synthesis of zinc-doped hydr…
View article: Influence of the Biological Medium on the Properties of Magnesium Doped Hydroxyapatite Composite Coatings
Influence of the Biological Medium on the Properties of Magnesium Doped Hydroxyapatite Composite Coatings Open
In this paper, the stability of magnesium-doped hydroxyapatite/chitosan (MHC) suspension obtained with the sol-gel approach was evaluated using nondestructive ultrasound measurements. The MHC coatings obtained by the spin-coating technique…
View article: Response of the Endogenous Antioxidant Defense System Induced in RAW 264.7 Macrophages upon Exposure to Dextran-Coated Iron Oxide Nanoparticles
Response of the Endogenous Antioxidant Defense System Induced in RAW 264.7 Macrophages upon Exposure to Dextran-Coated Iron Oxide Nanoparticles Open
Presently, iron oxide nanoparticles are the only ones approved for clinical use as contrast agents in magnetic resonance imaging (MRI). Even though there is a high demand for these types of nanoparticles both for clinical use as well as fo…